MCID: WRT003
MIFTS: 23

Warthin Tumor

Categories: Immune diseases, Rare diseases
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Aliases & Classifications for Warthin Tumor

MalaCards integrated aliases for Warthin Tumor:

Name: Warthin Tumor 19 16
Papillary Cystadenoma Lymphomatosum 19
Adenolymphoma 71

Classifications:



External Ids:

UMLS 71 C0001429

Summaries for Warthin Tumor

GARD: 19 Warthin tumor is a benign tumor of the salivary gland. The first symptom is usually a painless, slow-growing bump in front of the ear, on the bottom of the mouth, or under the chin. Though the cause is currently unknown, smoking is believed to increase the chance of developing Warthin tumor.

MalaCards based summary: Warthin Tumor, also known as papillary cystadenoma lymphomatosum, is related to pleomorphic adenoma and adenoma. An important gene associated with Warthin Tumor is KRT7 (Keratin 7). The drugs Ethanol and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, lymph node and thyroid.

Related Diseases for Warthin Tumor

Diseases related to Warthin Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 74)
# Related Disease Score Top Affiliating Genes
1 pleomorphic adenoma 10.5
2 adenoma 10.5
3 oncocytoma 10.5
4 cystadenoma 10.5
5 mucoepidermoid carcinoma 10.4
6 lymphoma 10.3
7 thyroid carcinoma 10.3
8 burkitt lymphoma 10.3
9 thyroid cancer, nonmedullary, 1 10.3
10 mikulicz disease 10.2
11 cystadenocarcinoma 10.2
12 papillary adenoma 10.2
13 turner syndrome 10.2
14 appendix adenocarcinoma 10.2
15 tubular adenocarcinoma 10.2
16 hashimoto thyroiditis 10.2
17 thyroiditis 10.2
18 parotid gland cancer 10.2
19 leukemia, chronic lymphocytic 10.1
20 lymphoma, hodgkin, classic 10.1
21 follicular lymphoma 10.1
22 necrotizing sialometaplasia 10.1
23 adenocarcinoma 10.1
24 breast ductal carcinoma 10.1
25 acinar cell carcinoma 10.1
26 papillary carcinoma 10.1
27 hyperhidrosis, gustatory 9.9
28 lipomatosis, multiple 9.9
29 sarcoidosis 1 9.9
30 down syndrome 9.9
31 lung cancer 9.9
32 sjogren syndrome 9.9
33 graves disease 1 9.9
34 ataxia with vitamin e deficiency 9.9
35 papillary thyroid microcarcinoma 9.9
36 langerhans cell histiocytosis 9.9
37 lymphoma, non-hodgkin, familial 9.9
38 meningioma, familial 9.9
39 sarcoidosis 2 9.9
40 lung cancer susceptibility 3 9.9
41 exanthem 9.9
42 diffuse large b-cell lymphoma 9.9
43 mantle cell lymphoma 9.9
44 peripheral t-cell lymphoma 9.9
45 ductal carcinoma in situ 9.9
46 lymphoblastic lymphoma 9.9
47 igg4-related disease 9.9
48 tongue carcinoma 9.9
49 parotitis 9.9
50 sialadenitis 9.9

Graphical network of the top 20 diseases related to Warthin Tumor:



Diseases related to Warthin Tumor

Symptoms & Phenotypes for Warthin Tumor

Drugs & Therapeutics for Warthin Tumor

Drugs for Warthin Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved 64-17-5 702
2 Anti-Infective Agents
3 Anti-Infective Agents, Local
4 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison Between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & Surgical Excision in Management of Warthin Tumor of Parotid Gland. Recruiting NCT05221736
2 Ultrasound-guided Radiofrequency Ablation of Parotid Warthin's Tumor Not yet recruiting NCT05078541

Search NIH Clinical Center for Warthin Tumor

Genetic Tests for Warthin Tumor

Anatomical Context for Warthin Tumor

Organs/tissues related to Warthin Tumor:

MalaCards : Salivary Gland, Lymph Node, Thyroid, Bone Marrow, Lung, Tongue, Pancreas

Publications for Warthin Tumor

Articles related to Warthin Tumor:

(show top 50) (show all 410)
# Title Authors PMID Year
1
Warthin tumor complicated with T-lymphoblastic lymphoma: a case report. 62
36416328 2022
2
NOR-1 (NR4A3) immunostaining on cytologic preparations for the preoperative diagnosis of acinic cell carcinoma of the salivary gland. 62
36058827 2022
3
Enhanced CT-based texture analysis and radiomics score for differentiation of pleomorphic adenoma, basal cell adenoma, and Warthin tumor of the parotid gland. 62
36367128 2022
4
Deep learning model developed by multiparametric MRI in differential diagnosis of parotid gland tumors. 62
35596805 2022
5
Point-of-care ultrasound scan as the primary modality for evaluating parotid tumors. 62
36258876 2022
6
Warthin-Like Papillary Thyroid Microcarcinoma With Coincidental Ipsilateral Warthin Tumor of the Parotid Gland Detected on 131I-SPECT/US and 18F-PET/US Fusion Imaging. 62
36252737 2022
7
Cytologic diagnosis of parotid gland Warthin tumor: Systematic review and meta-analysis. 62
35586869 2022
8
The Milan System classification of Warthin tumor: A large institutional study of 124 cases highlighting cytologic features that limit definitive interpretation. 62
35617489 2022
9
Multiple synchronous neoplasms in the ipsilateral parotid gland: case series. 62
35815451 2022
10
Distinguishing Parotid Polymorphic Adenoma and Warthin Tumor Based on the CT Radiomics Nomogram: A Multicenter Study. 62
35953356 2022
11
Apparent Diffusion Coefficient (ADC) Histogram Analysis in Parotid Gland Tumors: Evaluating a Novel Approach for Differentiation between Benign and Malignant Parotid Lesions Based on Full Histogram Distributions. 62
36010211 2022
12
Synchronous bilateral multifocal basal cell adenomas of the parotid gland-a case report. 62
35906614 2022
13
Ulcerative Warthin Tumor: A Case Report and Review of the Literature. 62
32931334 2022
14
Ultrasound-guided ethanol sclerotherapy for multifocal unilateral Warthin's tumor after partial parotidectomy. 62
35509301 2022
15
A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences. 62
35575610 2022
16
Heterotopic SMARCB1-deficient high-grade transformed/dedifferentiated acinic cell carcinoma and sine-qua-non radiology- pathology with TNM challenge. 62
35077953 2022
17
Management for Warthin Tumor of the Parotid Gland: Surgery or Observation. A 21-Year Retrospective Study of 387 Cases. 62
35393868 2022
18
Extraparotid Warthin Tumors Imitating Metastasis of Oral Cancers. 62
35602271 2022
19
Oral Squamous Cell Carcinoma and Warthin Tumour Occurring As Synchronous Tumours: A Report of Two Cases. 62
35345750 2022
20
NR4A3 Immunostain Is a Highly Sensitive and Specific Marker for Acinic Cell Carcinoma in Cytologic and Surgical Specimens. 62
34508546 2022
21
Usefulness of MRI-based radiomic features for distinguishing Warthin tumor from pleomorphic adenoma: performance assessment using T2-weighted and post-contrast T1-weighted MR images. 62
35757232 2022
22
Sebaceous Lymphadenoma of Parotid: Case Report of a Rare Entity. 62
35035169 2021
23
Risk Factors of Postoperative Facial Palsy for Benign Parotid Tumors: Outcome of 1,018 Patients. 62
34002863 2021
24
Diagnostic performance of qualitative and radiomics approach to parotid gland tumors: which is the added benefit of texture analysis? 62
34591597 2021
25
Machine learning-based multiparametric traditional multislice computed tomography radiomics for improving the discrimination of parotid neoplasms. 62
34650812 2021
26
Efficacy of computed tomography features in the differentiation of basal cell adenoma and Warthin tumor in the parotid gland. 62
33478930 2021
27
Post fine-needle aspiration near total infarction of Warthin tumor with squamous metaplasia: A diagnostic pitfall. 62
34427394 2021
28
Expressions of CXCL12, CXCL10 and CCL18 in Warthin tumors characterized pathologically by having a lymphoid stroma with germinal centers. 62
34124768 2021
29
Extracapsular Dissection for Small Benign Tumors of Parotid Gland: A Case Report on Contemporary Technique. 62
34540408 2021
30
Current Trends and Controversies in the Management of Warthin Tumor of the Parotid Gland. 62
34441400 2021
31
Warthin Tumor of the Caruncle: A Rare Case Report and Review of the Literature. 62
33481538 2021
32
The Role of FNAC in the Diagnosis and Management of Warthin Tumour: Analysis of 74 Cases. 62
34377171 2021
33
Surgeon-performed ultrasound with fine-needle aspiration biopsy for the diagnosis of parotid gland tumors. 62
33547678 2021
34
Sebaceous Lymphadenoma: Radiology-Pathology Correlation. 62
33398686 2021
35
Low Molecular Weight Cytokeratin Immunohistochemistry Reveals That Most Salivary Gland Warthin Tumors and Lymphadenomas Arise in Intraparotid Lymph Nodes. 62
32865726 2021
36
Crystalloids in FNA specimens of salivary gland lesions: A retrospective study in a single large institute. 62
33296146 2021
37
Assessing the diagnostic accuracy for pleomorphic adenoma and Warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi-institutional study. 62
33259150 2021
38
Reply to Assessing the diagnostic accuracy for pleomorphic adenoma and Warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi-institutional study. 62
33259142 2021
39
Clinicopathological features of incidental parotid lesions. 62
33757536 2021
40
Texture analysis in the characterization of parotid salivary gland lesions: A study on MR diffusion weighted imaging. 62
33453571 2021
41
Warthin Tumor Incidentally Detected on PET/CT Showing Both 68Ga-DOTANOC and 18F-FDG Uptake. 62
32956121 2021
42
[Performance of the magnetic resonance imaging in parotid gland tumor histopathology]. 62
34178238 2021
43
Classification of parotid gland tumors by using multimodal MRI and deep learning. 62
32886955 2021
44
Deep Learning for Differentiating Benign From Malignant Parotid Lesions on MR Images. 62
34249680 2021
45
Assessing the diagnostic accuracy for pleomorphic adenoma and Warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi-institutional study. 62
32767837 2021
46
Pediatric Warthin-like Mucoepidermoid Carcinoma: Report of Two Cases with One Persistent/Recurrent as Conventional Mucoepidermoid Carcinoma. 62
32221865 2020
47
Prevalence of Lymphoid Neoplasia in a Retrospective Analysis of Warthin Tumor: A Single Institution Experience. 62
32328910 2020
48
[Expression of NR4A3/NOR-1 in acinic cell carcinoma of the salivary gland]. 62
33152819 2020
49
Can Magnetic Resonance Radiomics Analysis Discriminate Parotid Gland Tumors? A Pilot Study. 62
33153140 2020
50
Differentiation of salivary gland tumors through tumor heterogeneity: a comparison between pleomorphic adenoma and Warthin tumor using CT texture analysis. 62
32621023 2020

Variations for Warthin Tumor

Expression for Warthin Tumor

Search GEO for disease gene expression data for Warthin Tumor.

Pathways for Warthin Tumor

GO Terms for Warthin Tumor

Sources for Warthin Tumor

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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