MCID: WTR001
MIFTS: 36

Waterhouse-Friderichsen Syndrome

Categories: Endocrine diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Waterhouse-Friderichsen Syndrome

MalaCards integrated aliases for Waterhouse-Friderichsen Syndrome:

Name: Waterhouse-Friderichsen Syndrome 12 74 52 58 43 15 17 71 32
Fatal Pneumococcal Waterhouse-Friderichsen Syndrome 52 71
Waterhouse-Friderichsen Syndrome, Meningococcal 71
Meningococcal Hemorrhagic Adrenalitis 12

Classifications:

Orphanet: 58  
Rare endocrine diseases


External Ids:

Disease Ontology 12 DOID:9931
MeSH 43 D014884
NCIt 49 C85225
ICD10 32 A39.1
MESH via Orphanet 44 D014884
ICD10 via Orphanet 33 A39.1+ E35.1*
UMLS via Orphanet 72 C0043068 C1403891
Orphanet 58 ORPHA100067
UMLS 71 C0043068 C1403891 C2931288

Summaries for Waterhouse-Friderichsen Syndrome

NIH Rare Diseases : 52 Waterhouse-Friderichsen syndrome is adrenal gland failure due to bleeding into the adrenal gland. It is usually caused by severe meningococcal infection or other severe, bacterial infection. Symptoms include acute adrenal gland insufficiency, and profound shock . Most patients with this condition are children, although adults may rarely be affected. It is deadly if not treated immediately.

MalaCards based summary : Waterhouse-Friderichsen Syndrome, also known as fatal pneumococcal waterhouse-friderichsen syndrome, is related to toxic shock syndrome and purpura. An important gene associated with Waterhouse-Friderichsen Syndrome is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. Affiliated tissues include adrenal gland, skin and spleen, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 An adrenal gland disease that is characterized by failure of the adrenal gland due to bleeding into the gland.

Wikipedia : 74 Waterhouse-Friderichsen syndrome (WFS) is defined as adrenal gland failure due to bleeding into the... more...

Related Diseases for Waterhouse-Friderichsen Syndrome

Diseases related to Waterhouse-Friderichsen Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 190, show less)
# Related Disease Score Top Affiliating Genes
1 toxic shock syndrome 31.0 SERPINC1 POMC F3
2 purpura 30.9 SERPINC1 F3 F2
3 disseminated intravascular coagulation 30.9 SERPINC1 F3 F2
4 purpura fulminans 30.7 SERPINC1 F3 F2
5 thrombophilia due to thrombin defect 30.1 SERPINC1 F3 F2
6 liver cirrhosis 29.7 SERPINC1 F3 F2
7 acute adrenal insufficiency 12.0
8 meningitis 10.9
9 meningococcemia 10.9
10 haemophilus influenzae 10.8
11 meningococcal infection 10.8
12 meningococcal meningitis 10.7
13 neisseria meningitidis infection 10.7
14 chickenpox 10.6
15 premature ovarian failure 7 10.5
16 exanthem 10.5
17 kidney cortex necrosis 10.5
18 shwartzman phenomenon 10.5
19 systemic lupus erythematosus 10.3
20 thrombocytopenic purpura, autoimmune 10.3
21 lipoid congenital adrenal hyperplasia 10.3
22 cyanosis, transient neonatal 10.3
23 streptococcus pneumonia 10.3
24 variola major 10.3
25 metabolic acidosis 10.3
26 cardiac arrest 10.3
27 optic papillitis 10.3
28 diarrhea 10.3
29 cholera 10.3
30 pericarditis 10.3
31 cholecystitis 10.3
32 poliomyelitis 10.3
33 peritonitis 10.3
34 scarlet fever 10.3
35 smallpox 10.3
36 cholangitis 10.3
37 encephalitis 10.3
38 fasciitis 10.3
39 necrotizing fasciitis 10.3
40 toxoplasmosis 10.3
41 hypoglycemia 10.3
42 47,xyy 10.3
43 sickle cell disease 10.3
44 back pain 10.3
45 thrombotic microangiopathy 10.3
46 medulloadrenal hyperfunction 10.3 POMC F3
47 adrenal rest tumor 10.3 POMC MC2R
48 corticosteroid-binding globulin deficiency 10.3 POMC MC2R
49 diabetes insipidus, neurohypophyseal 10.2 WFS1 POMC
50 glucocorticoid deficiency 1 10.2 POMC MC2R
51 steroid inherited metabolic disorder 10.2 POMC MC2R
52 adrenal cortical hypofunction 10.2 POMC MC2R
53 adrenal hypoplasia, congenital 10.2 POMC MC2R
54 heparin-induced thrombocytopenia 10.2 SERPINC1 F3
55 vulvar angiokeratoma 10.1 SERPINC1 F3
56 leech infestation 10.1 SERPINC1 F3
57 carotid artery thrombosis 10.1 SERPINC1 F3
58 achalasia-addisonianism-alacrima syndrome 10.1 POMC MC2R
59 achenbach syndrome 10.1 F3 F2
60 synovial angioma 10.1 F3 F2
61 renal pelvis squamous cell carcinoma 10.1 F3 F2
62 papillary adenofibroma 10.1 F3 F2
63 supine hypotensive syndrome 10.1 F2 ACR
64 emphysematous cholecystitis 10.1 F3 F2
65 femoral neuropathy 10.1 F3 F2
66 hemopneumothorax 10.1 F3 F2
67 gastric hemangioma 10.1 F3 F2
68 qualitative platelet defect 10.1 F3 F2
69 ankylosing spondylitis 1 10.1 F3 F2
70 hemopericardium 10.1 F3 F2
71 epidural abscess 10.1 F3 F2
72 cerebral sinovenous thrombosis 10.1 F3 F2
73 acth-independent macronodular adrenal hyperplasia 10.1 POMC MC2R
74 factor xii deficiency 10.1 SERPINC1 F3
75 mediastinitis 10.0 F3 F2
76 cerebral falx meningioma 10.0 F3 F2
77 intracranial hypotension 10.0 F3 F2
78 splenic sequestration 10.0 F3 F2
79 active peptic ulcer disease 10.0 F3 F2
80 acute hemorrhagic encephalitis 10.0 F3 F2
81 analbuminemia 10.0 F3 F2
82 hantavirus pulmonary syndrome 10.0 F3 F2
83 hemarthrosis 10.0 F3 F2
84 thrombasthenia 10.0 F3 F2
85 von willebrand disease, type 1 10.0 F3 F2
86 anuria 10.0 F3 F2
87 cardiac tamponade 10.0 F3 F2
88 spinal cord infarction 10.0 SERPINC1 F2
89 factor x deficiency 10.0 F3 F2
90 sudden sensorineural hearing loss 10.0 SERPINC1 F2
91 primary thrombocytopenia 10.0 F3 F2
92 adrenal cortex disease 10.0 POMC MC2R
93 tricuspid valve insufficiency 10.0 F3 F2
94 tricuspid valve disease 10.0 F3 F2
95 livedoid vasculitis 10.0 SERPINC1 F2
96 thoracic outlet syndrome 10.0 SERPINC1 F2
97 intermediate coronary syndrome 10.0 SERPINC1 F3
98 factor v deficiency 10.0 F3 F2
99 cholesterol embolism 10.0 SERPINC1 F2
100 prothrombin deficiency, congenital 10.0 SERPINC1 F2
101 branch retinal artery occlusion 10.0 SERPINC1 F2
102 cecal disease 10.0 F3 F2
103 retinal artery occlusion 10.0 SERPINC1 F2
104 mastoiditis 10.0 SERPINC1 F2
105 adrenal cortical carcinoma 10.0 POMC MC2R
106 aspiration pneumonia 10.0 F3 F2
107 central retinal artery occlusion 10.0 SERPINC1 F2
108 factor viii deficiency 9.9 F3 F2
109 sneddon syndrome 9.9 SERPINC1 F2
110 cortical blindness 9.9 F3 F2
111 ischemic colitis 9.9 SERPINC1 F2
112 pericardium disease 9.9 F3 F2
113 dysfibrinogenemia, congenital 9.9 SERPINC1 F2
114 intracranial hypertension, idiopathic 9.9 POMC F3 F2
115 retinal vascular occlusion 9.9 SERPINC1 F2
116 splenic disease 9.9 F3 F2
117 hypersplenism 9.9 SERPINC1 F2
118 speech and communication disorders 9.8 POMC F3 F2
119 abducens nerve disease 9.8 SERPINC1 POMC F2
120 hepatic veno-occlusive disease 9.8 SERPINC1 F3
121 protein c deficiency 9.7 SERPINC1 F2
122 thrombosis 9.7 SERPINC1 F3 F2
123 portal vein thrombosis 9.7 SERPINC1 F2
124 fournier gangrene 9.7 SERPINC1 F3 F2
125 blue toe syndrome 9.7 SERPINC1 F3 F2
126 lateral sinus thrombosis 9.7 SERPINC1 F3 F2
127 giant hemangioma 9.7 SERPINC1 F3 F2
128 dic in newborn 9.7 SERPINC1 F3 F2
129 hepatic infarction 9.7 SERPINC1 F3 F2
130 marantic endocarditis 9.7 SERPINC1 F3 F2
131 intracranial sinus thrombosis 9.7 SERPINC1 F3 F2
132 prothrombin deficiency 9.7 SERPINC1 F3 F2
133 sagittal sinus thrombosis 9.7 SERPINC1 F3 F2
134 intracranial embolism 9.7 SERPINC1 F3 F2
135 splenic infarction 9.7 SERPINC1 F3 F2
136 hepatic coma 9.7 SERPINC1 F3 F2
137 alpha-2-plasmin inhibitor deficiency 9.7 SERPINC1 F3 F2
138 vitamin k deficiency bleeding 9.7 SERPINC1 F3 F2
139 intracranial hypertension 9.7 SERPINC1 F3 F2
140 esophageal varix 9.7 SERPINC1 F3 F2
141 post-thrombotic syndrome 9.7 SERPINC1 F3 F2
142 papilledema 9.7 SERPINC1 F3 F2
143 intracranial thrombosis 9.7 SERPINC1 F3 F2
144 thrombophilia due to activated protein c resistance 9.7 SERPINC1 F3 F2
145 thrombophilia 9.7 SERPINC1 F3 F2
146 compartment syndrome 9.7 SERPINC1 F3 F2
147 peripheral vertigo 9.7 SERPINC1 F3 F2
148 factor xiii deficiency 9.7 SERPINC1 F3 F2
149 antithrombin iii deficiency 9.7 SERPINC1 F3 F2
150 thrombophlebitis 9.7 SERPINC1 F3 F2
151 mitral valve stenosis 9.7 SERPINC1 F3 F2
152 central retinal vein occlusion 9.7 SERPINC1 F3 F2
153 retinal vein occlusion 9.7 SERPINC1 F3 F2
154 coronary thrombosis 9.7 SERPINC1 F3 F2
155 autoimmune disease of cardiovascular system 9.7 SERPINC1 F3 F2
156 factor xi deficiency 9.7 SERPINC1 F3 F2
157 protein s deficiency 9.7 SERPINC1 F3 F2
158 inherited blood coagulation disease 9.7 SERPINC1 F3 F2
159 blood coagulation disease 9.7 SERPINC1 F3 F2
160 factor vii deficiency 9.7 SERPINC1 F3 F2
161 pulmonary artery disease 9.7 SERPINC1 F3 F2
162 hepatic vascular disease 9.7 SERPINC1 F3 F2
163 blood protein disease 9.7 SERPINC1 F3 F2
164 vein disease 9.7 SERPINC1 F3 F2
165 moyamoya disease 1 9.7 SERPINC1 F3 F2
166 budd-chiari syndrome 9.7 SERPINC1 F3 F2
167 placental insufficiency 9.7 SERPINC1 F3 F2
168 hemophilia b 9.7 SERPINC1 F3 F2
169 hemorrhagic disease 9.7 SERPINC1 F3 F2
170 heart conduction disease 9.7 SERPINC1 F3 F2
171 afibrinogenemia, congenital 9.7 SERPINC1 F3 F2
172 takayasu arteritis 9.7 SERPINC1 F3 F2
173 placenta disease 9.7 SERPINC1 F3 F2
174 antiphospholipid syndrome 9.7 SERPINC1 F3 F2
175 hemolytic-uremic syndrome 9.7 SERPINC1 F3 F2
176 thrombocytosis 9.7 SERPINC1 F3 F2
177 blood platelet disease 9.7 SERPINC1 F3 F2
178 pulmonary embolism 9.7 SERPINC1 F3 F2
179 hellp syndrome 9.7 SERPINC1 F3 F2
180 atrial heart septal defect 9.7 SERPINC1 F3 F2
181 peripheral vascular disease 9.7 SERPINC1 F3 F2
182 patent foramen ovale 9.7 SERPINC1 F3 F2
183 essential thrombocythemia 9.6 SERPINC1 F3 F2
184 placental abruption 9.5 SERPINC1 F2
185 atrial fibrillation 9.5 SERPINC1 F3 F2
186 cavernous sinus thrombosis 9.5 SERPINC1 POMC F3 F2
187 pericardial effusion 9.5 F3 F2
188 lemierre's syndrome 9.5 SERPINC1 F3 F2 ACR
189 diabetes mellitus 9.1 WFS1 SERPINC1 POMC F3 F2
190 endocardium disease 9.1 SERPINC1 SCIN F3 F2

Graphical network of the top 20 diseases related to Waterhouse-Friderichsen Syndrome:



Diseases related to Waterhouse-Friderichsen Syndrome

Symptoms & Phenotypes for Waterhouse-Friderichsen Syndrome

MGI Mouse Phenotypes related to Waterhouse-Friderichsen Syndrome:

45 (showing 2, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 F2 F3 MARCO MC2R POMC SCIN
2 immune system MP:0005387 9.17 F2 F3 MARCO MC2R POMC SCIN

Drugs & Therapeutics for Waterhouse-Friderichsen Syndrome

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Evaluation of Different Methods for Rapid Diagnosis of Meningitis in Assiut University Hospital Not yet recruiting NCT03759470

Search NIH Clinical Center for Waterhouse-Friderichsen Syndrome

Cochrane evidence based reviews: waterhouse-friderichsen syndrome

Genetic Tests for Waterhouse-Friderichsen Syndrome

Anatomical Context for Waterhouse-Friderichsen Syndrome

MalaCards organs/tissues related to Waterhouse-Friderichsen Syndrome:

40
Adrenal Gland, Skin, Spleen, Lung, Bone Marrow, Bone, Testes

Publications for Waterhouse-Friderichsen Syndrome

Articles related to Waterhouse-Friderichsen Syndrome:

(showing 285, show less)
# Title Authors PMID Year
1
Neisseria meningitidis Induced Fatal Waterhouse-Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure. 61
32192003 2020
2
Waterhouse-Friderichsen Syndrome in an Infant. 61
32234194 2020
3
A unique fatal case of Waterhouse-Friderichsen syndrome caused by Proteus mirabilis in an immunocompetent subject: Case report and literature analysis. 61
31441842 2019
4
The importance of the postmortem interval for the diagnosis of Waterhouse-Friderichsen syndrome by Neisseria meningitidis in a series of forensic cases. 61
31372361 2019
5
Rare case of meningococcal sepsis-induced testicular failure, primary hypothyroidism and hypoadrenalism: Is there a link? 61
30219775 2018
6
[The Waterhouse-Friderichsen syndrome]. 61
30040272 2018
7
A case report of spontaneous staphylococcal meningitis in a cynomolgus monkey. 61
29399828 2018
8
[Management of severe sepsis using a Cytokin-adsorber]. 61
29247319 2018
9
Why Asplenic Patients Should Not Take Care of the Neighbour's Dog? A Fatal Course of Capnocytophaga canimorsus Sepsis. 61
30174969 2018
10
A rare case of Waterhouse- Friderichsen syndrome during primary Varicella zoster infection. 61
29219830 2017
11
Atriobronchial Fistula Complicated by Septic Cerebral Air Emboli After Pulmonary Vein Ablation. 61
28441232 2017
12
Waterhouse-Friderichsen syndrome due to Neisseria meningitidis infection in a young adult with thrombotic microangiopathy and eculizumab treatment: case report and review of management. 61
28213751 2017
13
Streptococcus Pneumoniae Detection Long Time After Death in a Fatal Case of Waterhouse-Friderichsen Syndrome. 61
28009598 2017
14
[Dyspnea and skin rash in a 49-year-old male patient]. 61
27900398 2017
15
Fatal purpura fulminans and Waterhouse-Friderichsen syndrome from fulminant Streptococcus pneumoniae sepsis in an asplenic young adult. 61
27583208 2016
16
A Case of Waterhouse-Friderichsen Syndrome Resulting from an Invasive Pneumococcal Infection in a Patient with a Hypoplastic Spleen. 61
26942021 2016
17
A rare case of Waterhouse-Friderichsen syndrome caused by Capnocytophaga canimorsus in an immunocompetent patient. 61
25676131 2015
18
An autopsy case of pneumococcal Waterhouse-Friderichsen syndrome with possible functional asplenia/hyposplenia. 61
26261663 2015
19
Fatal Waterhouse-Friderichsen syndrome due to serotype C Neisseria meningitidis in a young HIV negative MSM (men who have sex with men). 61
25267809 2014
20
Waterhouse Friderichsen syndrome complicating fulminant Enterobacter cloacae sepsis in a preterm infant: the unresolved issue of corticosteroids. 61
24328998 2014
21
[Acute adrenal insufficiency. Easy to miss Waterhouse-Friderichsen syndrome, as shown in two cases]. 61
24187895 2013
22
A fatal case of streptococcal and meningococcal meningitis in a 2-years-old child occurring as Waterhouse-Friderichsen Syndrome. 61
23910860 2013
23
Adrenomegaly and septic adrenal hemorrhage (Waterhouse-Friderichsen syndrome) in the setting of congenital adrenal hyperplasia. 61
23814386 2013
24
The significance of adrenal hemorrhage: undiagnosed Waterhouse-Friderichsen syndrome, a case series. 61
23458363 2013
25
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. 61
23716842 2013
26
[Case report: A case of invasive pneumococcal disease with purpura fulminans and Waterhouse-Friderichsen syndrome]. 61
22693858 2012
27
Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways. 61
22072136 2011
28
A case of functional asplenia and pneumococcal sepsis. 61
21730800 2011
29
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. 61
21772601 2011
30
Fatal dog bite in the absence of significant trauma: Capnocytophaga canimorsus infection and unexpected death. 61
20407357 2010
31
Waterhouse-friderichsen syndrome caused by invasive haemophilus influenzae type B infection in a previously healthy young man. 61
20191807 2010
32
Systemic inflammatory response syndrome in nonhuman primates culminating in multiple organ failure, acute lung injury, and disseminated intravascular coagulation. 61
19773593 2009
33
Fatal pneumococcal Waterhouse-Friderichsen syndrome in a vaccinated adult with congenital asplenia. 61
19751638 2009
34
[Puerperal septic shock due to beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome]. 61
19287940 2009
35
[Foudroyant meningococcal sepsis in emergency medicine. Medical treatment and post-exposure prophylaxis]. 61
18270671 2008
36
Overwhelming postsplenectomy infection syndrome in adults - a clinically preventable disease. 61
18186551 2008
37
[Waterhouse-Friderichsen syndrome associated to a Morganella morganii and Enterococcus faecium peritonitis]. 61
17766079 2007
38
Medical image. Meningococcal septic shock with adrenal apoplexy--Waterhouse-Friderichsen syndrome. 61
16868589 2006
39
Invasive meningococcal disease associated with a very high case fatality rate in the North-West of Poland. 61
16487304 2006
40
Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. 61
16177250 2005
41
Case of Waterhouse Friderichsen Syndrome during outbreak of meningococcal disease in Delhi in May 2005. 61
16749283 2005
42
OPSI (overwhelming postsplenectomy infection) syndrome: a case report. 61
15639588 2004
43
[Special emergencies in dermatology]. 61
15133618 2004
44
Waterhouse-Friderichsen syndrome as a result of non-meningococcal infection. 61
14747454 2004
45
Cardiac rescue with enoximone in volume and catecholamine refractory septic shock. 61
14525645 2003
46
Fatal Waterhouse-Friderichsen syndrome due to Ewingella americana infection. 61
12604997 2003
47
Postmortem measurement of serum procalcitonin concentration in Waterhouse-Friderichsen syndrome. 61
12587602 2002
48
Serous flexor tenosynovitis as an associated finding in meningococcal septic polyarthritis. 61
11876283 2002
49
Waterhouse-Friderichsen syndrome after infection with group A streptococcus. 61
11702906 2001
50
Waterhouse-Friderichsen syndrome. 61
11556316 2001
51
Fatal pneumococcal Waterhouse-Friderichsen syndrome. 61
11482865 2001
52
Spontaneous Waterhouse-Friderichsen syndrome in a gang-housed baboon. 61
11515675 2001
53
Images in clinical medicine. Waterhouse-Friderichsen syndrome. 61
11333994 2001
54
[Secondary immunologically-caused myocarditis, pericarditis and exudative pleuritis due to meningococcal meningitis]. 61
11315579 2001
55
Community-acquired Acinetobacter meningitis in adults. 61
11139162 2000
56
Waterhouse-Friderichsen syndrome and bilateral renal cortical necrosis in meningococcal sepsis. 61
10922319 2000
57
Waterhouse-Friderichsen syndrome secondary to Capnocytophaga canimorsus septicemia and demonstration of bacteremia by peripheral blood smear. 61
10835521 2000
58
Reminder--necrotizing fasciitis complicated by Waterhouse-Friderichsen syndrome. 61
10454031 1999
59
Asplenia as a cause of sudden unexpected death in childhood. 61
10208339 1999
60
Familial epidemic of meningococcal disease. 61
9475810 1998
61
[A fatal case of overwhelming postsplenectomy infection syndrome developing 10 years after splenectomy]. 61
9256611 1997
62
[Fulminant infection outcome after splenectomy]. 61
9273546 1997
63
Treatment of thromboembolic complications of fulminant meningococcal septic shock. 61
9088469 1997
64
[Unilateral adrenal hemorrhage--a Waterhouse-Friderichsen syndrome?]. 61
8584912 1995
65
Changing epidemiology of meningococcal invasive disease in the Czech republic caused by new clone Neisseria meningitidis C:2a:P1.2(P1.5), ET-15/37. 61
8903519 1995
66
Lethal Waterhouse-Friderichsen syndrome in posttraumatic asplenia. 61
7473978 1995
67
Waterhouse-Friderichsen syndrome complicating primary biliary sepsis due to Pasteurella multocida in a patient with cirrhosis. 61
7560209 1995
68
[Diagnosis of an infected thrombus of the inferior vena cava with ultrasound and computerized tomography]. 61
7568797 1995
69
[Fulminant sepsis in a splenectomized patient. Waterhouse-Friderichsen syndrome due to pneumococcal sepsis]. 61
7800877 1994
70
[Cicatricial keloids after Waterhouse-Friderichsen syndrome]. 61
8150624 1994
71
Waterhouse-Friderichsen syndrome resulting from colchicine overdose. 61
8258815 1993
72
Fatal childhood pneumococcal Waterhouse-Friderichsen syndrome. 61
8451106 1993
73
Group A beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome. 61
1528655 1992
74
Haloalkylamine-induced renal papillary necrosis: a histopathological study of structure-activity relationships. 61
1768609 1991
75
[Recommendations for the diagnosis and therapy of meningitis, Waterhouse-Friderichsen syndrome and encephalitis in childhood]. 61
2098610 1990
76
Fatal pneumococcal bacteremia with disseminated intravascular coagulation and Waterhouse-Friderichsen syndrome in a vaccinated splenectomized adult. Case report. 61
2368552 1990
77
[Detection of soluble fibrin monomer complexes by the netropsin precipitation test in childhood meningitis]. 61
2160762 1990
78
[Waterhouse-Friderichsen syndrome in adults]. 61
2241795 1990
79
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b in an immunocompetent young adult. 61
2595428 1989
80
Pneumococcal Waterhouse-Friderichsen syndrome despite a normal spleen. 61
2608604 1989
81
[Haemophilus influenzae B meningitis and Waterhouse-Friderichsen syndrome in a 5-month-old infant]. 61
2485526 1989
82
[A case of Waterhouse-Friderichsen syndrome]. 61
2739266 1989
83
[Waterhouse-Friderichsen syndrome: surgical aspects]. 61
3311430 1987
84
Acute, massive, haemorrhagic adrenal necrosis experimentally produced by the Shwartzman mechanism in rabbits. 61
2825401 1987
85
Haemophilus influenzae meningitis and Waterhouse-Friderichsen syndrome in an adult. 61
3738579 1986
86
[Meningococcal epidemic in a boarding school: a rifampicin-resistant secondary case while under chemoprophylaxis]. 61
3094142 1986
87
[A case of successful treatment of Waterhouse-Friderichsen syndrome]. 61
3747430 1986
88
[Meningococcal infection with Waterhouse-Friderichsen syndrome--a case report with conclusions for the ambulatory care physician]. 61
3765683 1986
89
[False acute abdomen due to Waterhouse-Friderichsen syndrome]. 61
4021352 1985
90
Overwhelming post-splenectomy infection with Plesiomonas shigelloides in a patient cured of Hodgkin's disease. A case report. 61
3984949 1985
91
[Acute myocardial dysfunction in meningococcal septicemia]. 61
3983599 1985
92
Waterhouse-Friderichsen syndrome without purpura due to Haemophilus influenzae group B. 61
3873065 1985
93
[Waterhouse-Friderichsen syndrome in childhood]. 61
6727145 1984
94
[Case of Waterhouse-Friderichsen syndrome in the aged]. 61
6434648 1984
95
Apparent meningococcemia: clinical features of disease due to Haemophilus influenzae and Neisseria meningitidis. 61
6412207 1983
96
Adrenal, cutaneous and myocardial lesions in fulminating endotoxinemia (Waterhouse-Friderichsen syndrome). 61
7134067 1982
97
Clinicopathologic characteristics of septicemia in sickle cell disease. 61
7091069 1982
98
[Etiologic and pathogenetic factors in Waterhouse-Friderichsen syndrome (author's transl)]. 61
7102112 1982
99
Chest infection associated with the Waterhouse-Friderichsen syndrome. 61
6790062 1981
100
Waterhouse-Friderichsen syndrome caused by a DF-2 bacterium in a splenectomised patient. 61
7229096 1981
101
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b in an adult. 61
6977494 1981
102
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b. 61
316349 1979
103
[A case of Waterhouse-Friderichsen syndrome after splenectomy (author's transl)]. 61
439419 1979
104
[Meningococcemia with Waterhouse-Friderichsen syndrome]. 61
673603 1978
105
[Smallpox vaccination--Waterhouse-Friderichsen syndrome (author's transl)]. 61
416342 1978
106
[Waterhouse-Friderichsen-syndrome--clinical course and coagulation studies (author's transl)]. 61
746915 1978
107
[Morphology and pathogenesis of Waterhouse-Friderichsen-syndrome (author's transl)]. 61
746916 1978
108
Fatal cholera-like diarrhea with Waterhouse-Friderichsen syndrome, sickle-cell trait, and hyposplenism. 61
335288 1977
109
Relations between activation and inhibition of fibrinolysis in the walls of human arteries and veins. 61
579485 1977
110
[Waterhouse-Friderichsen syndrome during E. coli septicemia]. 61
333770 1977
111
Sudden death due to Waterhouse-Friderichsen syndrome and purulent leptomeningitis caused by Acinetobacter calcoaceticus (Mima polymorpha). 61
883428 1977
112
[Renal venous thrombosis and hemorrhagic renal infarction in septicemia and Waterhouse-Friderichsen syndrome]. 61
898962 1977
113
Adrenal lesions in calves dying from endotoxin shock, with special reference to the Waterhouse-Friderichsen syndrome. 61
858809 1977
114
[Waterhouse-Friderichsen syndrome]. 61
612742 1977
115
[Influence of pathogenesis of purulent meningitis on the prognosis (author's transl)]. 61
826805 1976
116
[A case of Waterhouse-Friderichsen syndrome]. 61
1004077 1976
117
Animal model of human disease. Waterhouse-Friderichsen syndrome. Animal model: Acrylonitrile-induced adrenal apoplexy. 61
1258981 1976
118
[Meningococcal infection with Waterhouse-Friderichsen syndrome and crural skin necrosis]. 61
969408 1976
119
[Clinical pathology of the Waterhouse-Friderichsen syndrome (author's transl)]. 61
814421 1976
120
Distribution and variation of fibrinolytic activity in the walls of human arteries and veins. 61
1017727 1976
121
Waterhouse Friderichsen syndrome. 61
1207489 1975
122
Hyposplenic, coagulopathic, cryptogenetic pneumococcemia. 61
1163492 1975
123
Postoperative adrenal hemorrhage. 61
1211987 1975
124
[Waterhouse-Friderichsen syndrome with fatal bleeding into the pleural cavity in the course of staphylococcal pneumonia]. 61
1116750 1975
125
[Morphological characteristics of meningococcemia in children]. 61
1200882 1975
126
[Waterhouse-Friderichsen syndrome during varicella in a child with toxoplasmosis]. 61
4850126 1974
127
[Waterhouse-Friderichsen syndrome]. 61
4411512 1974
128
[Pathological anatomy of Waterhouse-Friderichsen syndrome with special reference to disseminated intravascular coagulation]. 61
4632971 1973
129
Waterhouse Friderichsen syndrome. Endotoxin shock treated with massive doses of cortisol. 61
4705280 1973
130
[Treatment of meningococcemia, with special reference to the Waterhouse-Friderichsen syndrome]. 61
5043810 1972
131
[Waterhouse-Friderichsen syndrome: differential diagnosis, pathogenesis and treatment with streptokinase]. 61
5058423 1972
132
The Waterhouse-Friderichsen syndrome and its orthopaedic consequences. 61
5081691 1972
133
[Waterhouse-Friderichsen syndrome in a 7-day-old newborn infant due to Klebsiella pneumoniae]. 61
4550933 1972
134
[Meningococcal meningitis with symptoms of Waterhouse-Friderichsen syndrome in a patient with familial occurrence of systemic lupus erythematosus]. 61
5133313 1971
135
Disseminated intravascular coagulation and the Waterhouse-Friderichsen syndrome. 61
5118056 1971
136
[Clinical course of the Waterhouse-Friderichsen syndrome]. 61
5099065 1971
137
[A case of successful treatment of Waterhouse-Friderichsen syndrome. Pathogenesis and therapy]. 61
5548911 1971
138
The pathology of the Waterhouse-Friderichsen syndrome. 61
5504755 1970
139
Fulminating meningitis with Waterhouse-Friderichsen syndrome due to Neisseria gonorrhoeae. 61
4989197 1970
140
[On a case of Waterhouse-Friderichsen syndrome]. 61
5459583 1970
141
Waterhouse-Friderichsen syndrome induced by pneumococcemic shock. 61
5467531 1970
142
[Therapy of the Waterhouse-Friderichsen syndrome]. 61
5437718 1970
143
[Waterhouse-Friderichsen syndrome with favorable response to medical treatment]. 61
5528067 1970
144
[Pathogenesis and treatment of peracute meningococcal sepsis (Waterhouse-Friderichsen syndrome)]. 61
5522408 1970
145
[Waterhouse-Friderichsen syndrome in old age, without cutaneous hemorrhages, diagnosed during life]. 61
5415332 1970
146
[Treatment of Waterhouse-Friderichsen syndrome using heparin]. 61
5362158 1969
147
[On a case of Waterhouse-Friderichsen syndrome appearing shortly after antipoliomyelitic vaccination]. 61
5399584 1969
148
[2 cases of acute adrenal insufficiency with Waterhouse-Friderichsen syndrome]. 61
5802266 1969
149
[Waterhouse-Friderichsen syndrome with pneumococcal origin in a splenectomized microcythemic patient. (Probable pathogenetic importance of hepatic and bone marrow changes)]. 61
5781677 1969
150
[On a case of Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae]. 61
5314393 1969
151
[Waterhouse-Friderichsen syndrome with generalized gangrene of the extremities]. 61
5377032 1969
152
[Waterhouse-Friderichsen syndrome with acute symmetric acronecrosis]. 61
5765975 1969
153
Skin sloughs in Waterhouse-Friderichsen syndrome. Case report. 61
4881013 1968
154
Fatal meningitis due to Moraxella duplex: report of a case with Waterhouse-Friderichsen syndrome. 61
5655280 1968
155
[Metaproterenol in the treatment of irreversible shock in the Waterhouse-Friderichsen syndrome]. 61
5757056 1968
156
[Successful treatment of Waterhouse-Friderichsen syndrome with heparin]. 61
5595833 1967
157
[The treatment of Waterhouse-Friderichsen syndrome (in meningococcal sepsis) with trasylol]. 61
5301631 1967
158
Skin sloughing and peripheral gangrene in a case of Waterhouse-Friderichsen syndrome, probably caused by E. coli septicaemia. 61
4861368 1967
159
Three cases of Waterhouse--Friderichsen syndrome. 61
5618324 1967
160
A case of Waterhouse-Friderichsen Syndrome. 61
6028344 1967
161
[The Waterhouse-Friderichsen syndrome]. 61
5990248 1966
162
[Forum pathologicum. XXII. Waterhouse-Friderichsen syndrome]. 61
5985541 1966
163
[Clinical aspects of the Waterhouse-Friderichsen syndrome]. 61
5990977 1966
164
[WATERHOUSE-FRIDERICHSEN SYNDROME--CORTISONE THERAPY OR NOT?]. 61
14291130 1965
165
WATERHOUSE-FRIDERICHSEN SYNDROME. 61
14284854 1965
166
ENDOTOXEMIA AND ADRENAL HEMORRHAGE. A MECHANISM FOR THE WATERHOUSE-FRIDERICHSEN SYNDROME. 61
14264270 1965
167
[THE WATERHOUSE-FRIDERICHSEN SYNDROME]. 61
14183299 1964
168
[2 CASES OF WATERHOUSE-FRIDERICHSEN SYNDROME]. 61
14187510 1964
169
[WATERHOUSE-FRIDERICHSEN SYNDROME FOLLOWING SPLENECTOMY FOR CONGENITAL SPHEROCYTOSIS IN A 19-MONTH-OLD BOY]. 61
14182847 1964
170
[WATERHOUSE-FRIDERICHSEN SYNDROME OF PNEUMOCOCCAL ETIOLOGY]. 61
14142339 1964
171
[Waterhouse-Friderichsen syndrome developing in mother and child]. 61
13986609 1963
172
Repair after gangrene due to Waterhouse-Friderichsen syndrome. 61
14479206 1962
173
Multiple coagulative defects in a patient with the Waterhouse-Friderichsen syndrome. 61
14490551 1962
174
[On the pathogenesis and therapy of the Waterhouse-Friderichsen syndrome]. 61
13917949 1961
175
[Waterhouse-Friderichsen syndrome]. 61
13871052 1961
176
[Waterhouse-Friderichsen syndrome. Treatment; study of the sequelae]. 61
13760816 1961
177
[Apropos of Waterhouse-Friderichsen syndrome with illustration of a case]. 61
13723895 1960
178
[The Waterhouse-Friderichsen syndrome]. 61
13776390 1960
179
Waterhouse-Friderichsen syndrome in varicella. 61
13772211 1960
180
[Fatal acute adrenal insufficiency caused by bilateral apoplexy of the adrenal glands (Waterhouse-Friderichsen syndrome) following anti-poliomyelitis vaccination]. 61
13683946 1960
181
[Waterhouse-Friderichsen syndrome. III. Therapeutic management]. 61
13682143 1960
182
[Enterococcal purpura fulminans (Waterhouse-Friderichsen syndrome)]. 61
13691880 1960
183
Fatal "Waterhouse-Friderichsen syndrome" due to dicumarol. 61
13824302 1960
184
[Post-abortion sepsis. Massive bilateral adrenal hemorrhage. Waterhouse-Friderichsen syndrome]. 61
13821730 1959
185
WATERHOUSE-Friderichsen syndrome. 61
13856902 1959
186
[The Waterhouse-Friderichsen syndrome]. 61
13824679 1959
187
[Scarlatina; Marchand-Waterhouse-Friderichsen syndrome; and hypotonic dehydration or salt depletion]. 61
14414087 1959
188
Fulminating meningococcemia (Waterhouse-Friderichsen syndrome): report of two patients successfully treated with chemotherapy, vasopressors, and adrenal steroids. 61
13664537 1959
189
[Purpura fulminans infectious (Waterhouse-Friderichsen syndrome]. 61
13638821 1959
190
[Waterhouse-Friderichsen syndrome]. 61
13839582 1959
191
[Waterhouse-Friderichsen syndrome]. 61
13846517 1959
192
[Hemorrhage of the adrenal gland in 2 newborn infants (Waterhouse-Friderichsen syndrome)]. 61
13840135 1959
193
[Subacute post-abortal septicemia of perfringens type with Waterhouse-Friderichsen syndrome]. 61
13617752 1958
194
[Waterhouse-Friderichsen syndrome]. 61
13582638 1958
195
Memingococcal Septicaemia with Bilateral Adrenal Haemorrhage (Waterhouse-Friderichsen Syndrome): Clinical Pathological Conference. 61
28907875 1958
196
[3 Cases of Waterhouse-Friderichsen syndrome treated with noradrenalin with 2 successes]. 61
13561106 1958
197
Necrotizing renal papillitis review and report of a case treated by nephrectomy and complicated by Waterhouse-Friderichsen syndrome. 61
13512121 1958
198
Meningococcic meningitis and meningococcemia with probable Waterhouse-Friderichsen syndrome. 61
13514273 1958
199
[An adult case of Waterhouse-Friderichsen syndrome]. 61
13472930 1957
200
The early diagnosis of the Waterhouse-Friderichsen syndrome. 61
13435437 1957
201
[Waterhouse-Friderichsen syndrome]. 61
13494062 1957
202
THE WATERHOUSE-FRIDERICHSEN syndrome failure of hydrocortisone therapy. 61
13398680 1957
203
Recovery from Waterhouse-Friderichsen syndrome associated with use of norepinephrine to combat shock. 61
13385639 1957
204
Congenital absence of the spleen in an adult; report of a case associated with recurrent Waterhouse-Friderichsen syndrome. 61
13322226 1956
205
[Waterhouse-Friderichsen syndrome complicated by hypernatremia and hyperchloremia of cerebral origin]. 61
13309781 1956
206
[Waterhouse-Friderichsen syndrome]. 61
13311550 1956
207
Fulminating meningococcemia and meningitis with vascular collapse; report of a case of Waterhouse-Friderichsen syndrome with recovery. 61
14397040 1955
208
[Waterhouse-Friderichsen syndrome]. 61
13251353 1955
209
[Improved prognosis in the Waterhouse-Friderichsen syndrome]. 61
14387708 1955
210
Waterhouse-Friderichsen syndrome (W.-F.S.) 61
14375664 1955
211
Acute adrenal insufficiency (Waterhouse-Friderichsen syndrome) treated with cortisone. 61
14352101 1955
212
Waterhouse-Friderichsen syndrome: report of a case with recovery. 61
14350471 1955
213
[A cured case of Waterhouse-Friderichsen-syndrome]. 61
14374790 1955
214
[Contribution to the therapy of Waterhouse-Friderichsen syndrome; treatment with cortisone and bacitracin]. 61
13254077 1955
215
Meningococcal infections; with particular reference to fulminating meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and norepinephrine. 61
13202023 1954
216
The treatment of Waterhouse-Friderichsen syndrome; brief review of the literature and report of one case. 61
13195875 1954
217
[Clinical aspects and pathological anatomy of the Waterhouse-Friderichsen syndrome]. 61
13214797 1954
218
[Peracute meningococcal infection (Waterhouse Friderichsen syndrome)]. 61
13200202 1954
219
Waterhouse-Friderichsen syndrome. 61
13163651 1954
220
Mima polymorpha as a causative agent in Waterhouse-Friderichsen syndrome. 61
13157230 1954
221
[On the increase of meningococcal infections with Waterhouse-Friderichsen syndrome]. 61
13161602 1954
222
[Waterhouse-Friderichsen syndrome]. 61
13166306 1954
223
[Meningococcal meningitis with Waterhouse-Friderichsen syndrome cured with cortisone and antibiotics]. 61
13168285 1954
224
Waterhouse-Friderichsen syndrome; a review of the literature and a report of two cases of fulminating meningococcic septicemia. 61
13199914 1954
225
[Waterhouse-Friderichsen syndrome in a 61-year old woman]. 61
13166236 1954
226
[The Waterhouse-Friderichsen syndrome; a clinical evaluation]. 61
13229959 1954
227
[Pathogenesis of Waterhouse-Friderichsen syndrome]. 61
13205580 1954
228
[Therapy of Waterhouse-Friderichsen syndrome]. 61
13146068 1954
229
[Therapy of peracute meningococcal infection (Waterhouse-Friderichsen syndrome)]. 61
13128601 1953
230
Norepinephrine in the treatment of the Waterhouse-Friderichsen syndrome; report of a case. 61
13098452 1953
231
Nor-epinephrine in the treatment of acute meningococcemia with shock (Waterhouse-Friderichsen syndrome) and an evaluation of adrenocortical function. 61
13072798 1953
232
Waterhouse-Friderichsen syndrome of nonmeningococcal origin in an adult woman. 61
13067057 1953
233
Waterhouse Friderichsen syndrome. 61
13071144 1953
234
[A case of Waterhouse-Friderichsen syndrome cured with cortisone]. 61
13098197 1953
235
The prolonged Waterhouse-Friderichsen syndrome with renal and myocardial insufficiency. 61
13031407 1953
236
A fatal case of Still's disease associated with Waterhouse-Friderichsen syndrome due to pneumococcal septicaemia. 61
13036557 1953
237
Lung: osseous emboli after spinal tap in a case of Waterhouse-Friderichsen syndrome complicating preeclamptic toxemia. 61
13094139 1953
238
The Waterhouse-Friderichsen syndrome. 61
13050387 1953
239
Meningococcus meningitis with massive hemorrhage of the adrenals' (Waterhouse-Friderichsen syndrome) complicating pregnancy with pre-eclamptic toxemia. 61
13016690 1953
240
Waterhouse-Friderichsen syndrome associated with septic abortion and sickle cell disease. 61
13002737 1952
241
Waterhouse-Friderichsen syndrome; report of a case with recovery. 61
14947936 1952
242
Waterhouse-Friderichsen syndrome treated with cortisone; report of two cases. 61
14928604 1952
243
[Waterhouse Friderichsen syndrome]. 61
12982631 1952
244
[Clinical and statistical considerations on 26 cases of Waterhouse-Friderichsen syndrome]. 61
14943535 1952
245
A case of Waterhouse-Friderichsen syndrome with recovery following the use of cortisone, aqueous adrenal cortical extract and chemotherapy. 61
14918718 1952
246
A case of Waterhouse-Friderichsen syndrome due to hemophilus influenzae. 61
14880706 1951
247
[Two cases of the Waterhouse-Friderichsen syndrome]. 61
14884675 1951
248
[The Waterhouse-Friderichsen syndrome]. 61
14863455 1951
249
[Marchand-Waterhouse-Friderichsen syndrome]. 61
14883527 1951
250
Waterhouse-Friderichsen syndrome; report of cure effected with cortisone. 61
14850261 1951
251
Nature of Waterhouse-Friderichsen syndrome; report of case with successful treatment with cortisone. 61
14850251 1951
252
[Waterhouse-Friderichsen syndrome in a subject with prior lesions of the adrenals]. 61
14892703 1951
253
Waterhouse-Friderichsen syndrome (?) with recovery. 61
14825073 1951
254
[Waterhouse-Friderichsen syndrome]. 61
14854471 1951
255
[Marchand-Waterhouse-Friderichsen syndrome]. 61
14834022 1951
256
The Waterhouse-Friderichsen syndrome in the differential diagnosis of acute abdominal crises. 61
14782113 1950
257
[A case of Waterhouse-Friderichsen syndrome]. 61
14806284 1950
258
[Hemorrhagi forms of epidemic cerebrospinal meningitis; the Waterhouse-Friderichsen syndrome]. 61
15435395 1950
259
CLINICAL-pathological conference: Waterhouse-Friderichsen syndrome. 61
15419978 1950
260
[Fulminating meningococcus septicemia; Waterhouse-Friderichsen syndrome]. 61
15440269 1950
261
[Experimental study on bilateral apoplexy of the adrenals; Waterhouse-Friderichsen syndrome]. 61
15440122 1950
262
[Waterhouse-Friderichsen syndrome]. 61
15413500 1950
263
The Waterhouse-Friderichsen syndrome; report of a case. 61
15434890 1950
264
Waterhouse-Friderichsen syndrome. 61
18125262 1949
265
Fulminating meningococcic infections and the so-called Waterhouse-Friderichsen syndrome. 61
18874411 1948
266
Waterhouse-Friderichsen syndrome in an adult. 61
20265341 1947
267
The Waterhouse-Friderichsen syndrome in urology. 61
20266249 1947
268
Waterhouse-Friderichsen syndrome complicated by acute pericarditis, with recovery. 61
20250341 1947
269
Massive gastro-intestinal hemorrhage in fulminating meningococcus meningitis (Waterhouse-Friderichsen syndrome) with recovery. 61
20246682 1947
270
Waterhouse-Friderichsen syndrome; recovery from shock in fatal case. 61
20292900 1947
271
A case of fulminating meningococcemia exhibiting the Waterhouse-Friderichsen syndrome and demonstrating the value of cortical extract administration. 61
20286912 1947
272
Experimental study of purpuric meningococcemia in relation to the Shwartzmann phenomenon; with discussion of meningococcic purpura, the Waterhouse-Friderichsen syndrome and bilateral renal cortical necrosis. 61
20284509 1947
273
The Waterhouse-Friderichsen syndrome; with a review of the literature and an addition of three new cases from the Charity Hospital of Louisiana. 61
20277676 1946
274
Waterhouse-Friderichsen syndrome. 61
20997496 1946
275
Two cases of Waterhouse-Friderichsen syndrome in the same family, one with recovery under penicillin therapy. 61
20997708 1946
276
Possible Waterhouse-Friderichsen syndrome with recovery. 61
20997539 1946
277
Bilateral acute hemorrhagic necrosis of the adrenals in a young child (a case of Waterhouse-Friderichsen syndrome). 61
21066827 1946
278
Fulminating meningococcemia with vascular collapse (Waterhouse-Friderichsen syndrome); report on four adult patients who recovered. 61
21018881 1946
279
Bilateral acute hemorrhagic necrosis of the adrenals (Waterhouse-Friderichsen syndrome) in a young child. 61
20245933 1946
280
Waterhouse-Friderichsen syndrome; report of case with recovery. 61
21004158 1945
281
Waterhouse-Friderichsen syndrome; report of a case. 61
21009674 1945
282
The Waterhouse-Friderichsen Syndrome: Report of Three Cases in Adults with Necropsy Findings. 61
21434244 1945
283
Fulminating Septicaemia associated with Purpura and Adrenal Haemorrhage (Waterhouse-Friderichsen Syndrome). 61
20783292 1940
284
ADRENAL HAEMORRHAGE (WATERHOUSE-FRIDERICHSEN SYNDROME) IN A YOUNG CHILD. 61
20320885 1938
285
PANMYELOPHTHISIS WITH HEMORRHAGIC MANIFESTATIONS IN RATS ON A NUTRITIONAL BASIS. 61
19870685 1937

Variations for Waterhouse-Friderichsen Syndrome

Expression for Waterhouse-Friderichsen Syndrome

Search GEO for disease gene expression data for Waterhouse-Friderichsen Syndrome.

Pathways for Waterhouse-Friderichsen Syndrome

Pathways related to Waterhouse-Friderichsen Syndrome according to GeneCards Suite gene sharing:

(showing 2, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.33 SERPINC1 F3 F2
2 10.96 SERPINC1 F3 F2

GO Terms for Waterhouse-Friderichsen Syndrome

Cellular components related to Waterhouse-Friderichsen Syndrome according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 SERPINC1 POMC F3 F2 CST11 ACR

Biological processes related to Waterhouse-Friderichsen Syndrome according to GeneCards Suite gene sharing:

(showing 4, show less)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.43 WFS1 SERPINC1 F2
2 blood coagulation GO:0007596 9.33 SERPINC1 F3 F2
3 regulation of blood coagulation GO:0030193 8.96 SERPINC1 F2
4 hemostasis GO:0007599 8.8 SERPINC1 F3 F2

Molecular functions related to Waterhouse-Friderichsen Syndrome according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.13 F3 F2 ACR
2 protease binding GO:0002020 8.8 SERPINC1 F3 ACR

Sources for Waterhouse-Friderichsen Syndrome

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33 ICD10 via Orphanet
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