MCID: WDR002
MIFTS: 6

Wdr26-Related Intellectual Disability

Aliases & Classifications for Wdr26-Related Intellectual Disability

MalaCards integrated aliases for Wdr26-Related Intellectual Disability:

Name: Wdr26-Related Intellectual Disability 24

Summaries for Wdr26-Related Intellectual Disability

MalaCards based summary : Wdr26-Related Intellectual Disability is related to alacrima, achalasia, and mental retardation syndrome and hypotonia. An important gene associated with Wdr26-Related Intellectual Disability is WDR26 (WD Repeat Domain 26).

GeneReviews: NBK540448

Related Diseases for Wdr26-Related Intellectual Disability

Diseases related to Wdr26-Related Intellectual Disability via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 alacrima, achalasia, and mental retardation syndrome 10.3
2 hypotonia 10.3

Symptoms & Phenotypes for Wdr26-Related Intellectual Disability

Drugs & Therapeutics for Wdr26-Related Intellectual Disability

Search Clinical Trials , NIH Clinical Center for Wdr26-Related Intellectual Disability

Genetic Tests for Wdr26-Related Intellectual Disability

Anatomical Context for Wdr26-Related Intellectual Disability

Publications for Wdr26-Related Intellectual Disability

Articles related to Wdr26-Related Intellectual Disability:

(show all 18)
# Title Authors PMID Year
1
Phenotypic features of 1q41q42 microdeletion including WDR26 and FBXO28 are clinically recognizable: The first case from Japan. 4
30635136 2019
2
A novel FBXO28 frameshift mutation in a child with developmental delay, dysmorphic features, and intractable epilepsy: A second gene that may contribute to the 1q41-q42 deletion phenotype. 4
30160831 2018
3
WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features. 4
28686853 2017
4
Timing, rates and spectra of human germline mutation. 4
26656846 2016
5
FBXO28 is a critical gene of the 1q41q42 microdeletion syndrome. 4
25900767 2015
6
Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures. 4
24357076 2014
7
WDR26 functions as a scaffolding protein to promote Gβγ-mediated phospholipase C β2 (PLCβ2) activation in leukocytes. 4
23625927 2013
8
Genomic alterations that contribute to the development of isolated and non-isolated congenital diaphragmatic hernia. 4
21525063 2011
9
New cases and refinement of the critical region in the 1q41q42 microdeletion syndrome. 4
20951845 2011
10
Characterization of the chromosome 1q41q42.12 region, and the candidate gene DISP1, in patients with CDH. 4
20799323 2010
11
WD40 proteins propel cellular networks. 4
20451393 2010
12
Interstitial deletion 1q42 in a patient with agenesis of corpus callosum: Phenotype-genotype comparison to the 1q41q42 microdeletion suggests a contiguous 1q4 syndrome. 4
20358614 2010
13
Sequence variants in the HLX gene at chromosome 1q41-1q42 in patients with diaphragmatic hernia. 4
19459883 2009
14
The discovery of microdeletion syndromes in the post-genomic era: review of the methodology and characterization of a new 1q41q42 microdeletion syndrome. 4
17873649 2007
15
Chromosome abnormalities in two patients with features of autosomal dominant Robinow syndrome. 4
17603805 2007
16
Microdissection-based high-resolution genomic array analysis of two patients with cytogenetically identical interstitial deletions of chromosome 1q but distinct clinical phenotypes. 4
16835927 2006
17
WDR26: a novel Gbeta-like protein, suppresses MAPK signaling pathway. 4
15378603 2004
18
WDR26-Related Intellectual Disability 38
31021590 2019

Variations for Wdr26-Related Intellectual Disability

Expression for Wdr26-Related Intellectual Disability

Search GEO for disease gene expression data for Wdr26-Related Intellectual Disability.

Pathways for Wdr26-Related Intellectual Disability

GO Terms for Wdr26-Related Intellectual Disability

Sources for Wdr26-Related Intellectual Disability

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....