MCID: WTB001
MIFTS: 20

Wet Beriberi

Categories: Cardiovascular diseases, Metabolic diseases, Respiratory diseases

Aliases & Classifications for Wet Beriberi

MalaCards integrated aliases for Wet Beriberi:

Name: Wet Beriberi 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0070317
ICD10 33 E51.12

Summaries for Wet Beriberi

Disease Ontology : 12 A beriberi that is located in the cardiovascular system and has symptom increased heart rate, swelling of lower legs, and shortness of breath.

MalaCards based summary : Wet Beriberi is related to beriberi and dry beriberi, and has symptoms including increased heart rate The drugs Folic acid and Thiamine have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and cardiovascular system.

Wikipedia : 75 Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B1). A severe and chronic... more...

Related Diseases for Wet Beriberi

Diseases related to Wet Beriberi via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 beriberi 12.2
2 dry beriberi 11.9
3 polyneuropathy 10.4
4 lactic acidosis 10.4
5 neuropathy 10.3
6 wernicke-korsakoff syndrome 10.2
7 wernicke encephalopathy 10.2
8 peripheral nervous system disease 10.2
9 encephalopathy 10.2
10 hypoascorbemia 10.1
11 graves disease 1 10.1
12 ataxia and polyneuropathy, adult-onset 10.1
13 kearns-sayre syndrome 10.1
14 metabolic acidosis 10.1
15 withdrawal disorder 10.1
16 pulmonary edema 10.1
17 hemopericardium 10.1
18 pericardial effusion 10.1
19 poems syndrome 10.1
20 toxic shock syndrome 10.1
21 critical illness polyneuropathy 10.1
22 alcohol use disorder 10.1
23 pericarditis 10.1
24 eating disorder 10.1
25 pathologic nystagmus 10.1

Graphical network of the top 20 diseases related to Wet Beriberi:



Diseases related to Wet Beriberi

Symptoms & Phenotypes for Wet Beriberi

Symptoms:

12
  • increased heart rate

Drugs & Therapeutics for Wet Beriberi

Drugs for Wet Beriberi (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
2
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 2 59-43-8, 70-16-6 1130
3 Micronutrients Phase 2
4 Trace Elements Phase 2
5 Vitamins Phase 2
6 Vitamin B Complex Phase 2
7 Vitamin B9 Phase 2
8 Folate Phase 2
9 Nutrients Phase 2
10 Thiamin Phase 2
11 diuretics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effect of Thiamine vs. Placebo on VO2 in Critical Illness Completed NCT01985685 Phase 2 Thiamine
2 Thiamine Supplementation to Improve Cardiac Function in Patients With Congestive Heart Failure on Long-term Treatment With Diuretic Drugs Completed NCT00770107 Thiamine;Placebo
3 The Effect of Thiamine on VO2 Levels in Critically Ill Patients Completed NCT01462279 Thiamine

Search NIH Clinical Center for Wet Beriberi

Genetic Tests for Wet Beriberi

Anatomical Context for Wet Beriberi

MalaCards organs/tissues related to Wet Beriberi:

41
Heart, Endothelial

The Foundational Model of Anatomy Ontology organs/tissues related to Wet Beriberi:

19
Cardiovascular System

Publications for Wet Beriberi

Articles related to Wet Beriberi:

(show all 40)
# Title Authors PMID Year
1
Role of Thiamin in Health and Disease. 38
30644592 2019
2
Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature. 38
30862772 2019
3
Beriberi disease in an 11-year-old girl with total colectomy. 38
30397502 2018
4
Thiamine and Cardiovascular Disease: A Literature Review. 38
29360523 2018
5
Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: A case report and literature review. 38
29489643 2018
6
Wet Beriberi Associated with Hikikomori Syndrome. 38
29188542 2018
7
Case report: pericardial effusion with constrictive physiology in a patient with wet beriberi. 38
27059308 2016
8
High-Output Heart Failure Caused by Thyrotoxicosis and Beriberi. 38
26567494 2015
9
Wernicke's Encephalopathy, Wet Beriberi, and Polyneuropathy in a Patient with Folate and Thiamine Deficiency Related to Gastric Phytobezoar. 38
26697247 2015
10
[Thiamine deficiency in infants: a case report]. 38
24636593 2014
11
Shoshin beriberi induced by long-term administration of diuretics: a case report. 38
25105030 2014
12
Total parenteral nutrition caused Wernicke's encephalopathy accompanied by wet beriberi. 38
24516692 2014
13
"Dry" and "wet" beriberi mimicking critical illness polyneuropathy. 38
24339610 2013
14
Altered and unstable: wet beriberi, a clinical review. 38
23849362 2013
15
An eating disorder leading to wet beriberi heart failure in a 30-year-old woman. 38
23158607 2013
16
Increase of serum vascular endothelial growth factors in wet beriberi: two case reports. 38
22504253 2012
17
Cardiovascular magnetic resonance in wet beriberi. 38
21838901 2011
18
A new crystal form of mouse thiamin pyrophosphokinase. 38
21552434 2011
19
Outbreak of beriberi among African Union troops in Mogadishu, Somalia. 38
22205947 2011
20
Cardiac beriberi: often a missed diagnosis. 38
19934228 2010
21
Characteristics of thiamin and its relevance to the management of heart failure. 38
18849553 2008
22
Thiamin deficiency as a cause of reversible cor pulmonale. 38
18660937 2008
23
Loop diuretic therapy, thiamine balance, and heart failure. 38
17673878 2007
24
[A man with the combination of dry and wet beriberi]. 38
16808367 2006
25
Increased troponin I in "wet" beriberi. 38
16644891 2006
26
Pyrithiamine as a substrate for thiamine pyrophosphokinase. 38
16365036 2006
27
Thiamine deficiency and beriberi features in a patient with hyperemesis gravidarum. 38
15979284 2005
28
Gene-environment interactions in wet beriberi: effects of thiamine depletion in CD36-defect rats. 38
12969879 2003
29
Molecular mechanisms of thiamine utilization. 38
11899071 2001
30
[Cardiac beriberi]. 38
10816808 2000
31
Diuretic use: a risk for subclinical thiamine deficiency in elderly patients. 38
10842416 2000
32
Severe acidosis and hyperdynamic circulation in a 39-year-old alcoholic. 38
9696175 1998
33
Beriberi in a well-nourished Amazonian population. 38
9698265 1998
34
[Scurvy with simultaneous wet beriberi in 2 patients]. 38
7809869 1994
35
[A case of wet beriberi]. 38
2623323 1989
36
Carbonated drinks, thiamine deficiency and right ventricular failure. 38
3441782 1987
37
Chronic cardiac beriberi in a former prisoner of the Japanese. 38
7437412 1980
38
Wet beriberi in an alcoholic. 38
1139239 1975
39
John Blackall's observations on the relation between nutritional deprivation and wet beriberi. 38
13348836 1956
40
[Wet beriberi]. 38
13122862 1953

Variations for Wet Beriberi

Expression for Wet Beriberi

Search GEO for disease gene expression data for Wet Beriberi.

Pathways for Wet Beriberi

GO Terms for Wet Beriberi

Sources for Wet Beriberi

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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