Aliases & Classifications for Whiplash

MalaCards integrated aliases for Whiplash:

Name: Whiplash 55

Summaries for Whiplash

NINDS : 55 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to pain - chronic and headache. An important gene associated with Whiplash is IL16 (Interleukin 16), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Central Nervous System Depressants and Peripheral Nervous System Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Wikipedia : 77 Whiplash is a 2014 American drama film written and directed by Damien Chazelle. It depicts the... more...

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
# Related Disease Score Top Affiliating Genes
1 pain - chronic 10.6
2 headache 10.6
3 depression 10.4
4 fibromyalgia 10.4
5 head injury 10.3
6 anxiety 10.2
7 inclusion conjunctivitis 10.2 CCL5 IL16
8 brain injury 10.2
9 oral lichen planus 10.2 CCL5 CCR5
10 yellow fever 10.1 CCL5 CCR5
11 omsk hemorrhagic fever 10.1 CCL4 CCL5
12 caronte 10.1
13 traumatic brain injury 10.1
14 amnestic disorder 10.1
15 thoracic outlet syndrome 10.1
16 radiculopathy 10.1
17 pulmonary sarcoidosis 10.1 CCL5 CCR5
18 acute cervicitis 10.1 CCL4 CCL5
19 autoimmune disease of central nervous system 10.1 CCL5 CCR5
20 mycetoma 10.1 CCL5 COMT
21 spinal cord injury 10.1
22 dermatitis 10.1
23 post-traumatic stress disorder 10.0
24 dystonia 10.0
25 respiratory syncytial virus infectious disease 10.0 CCL3 CCL5
26 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 9.9 CCL4 CCR5
27 cytomegalovirus infection 9.9 CCL3 CCL5
28 necatoriasis 9.9 CCL3 CCL4
29 bronchiolitis 9.9 CCL3 CCL5
30 trypanosomiasis 9.8 CCL3 CCL5
31 night blindness, congenital stationary, type 1a 9.8 CCL3 CCL4
32 carpal tunnel syndrome 9.8
33 systemic lupus erythematosus 9.8
34 migraine with or without aura 1 9.8
35 vertigo, benign recurrent 9.8
36 body mass index quantitative trait locus 1 9.8
37 mononeuropathy of the median nerve, mild 9.8
38 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8
39 bipolar disorder 9.8
40 hydrocephalus 9.8
41 joint disorders 9.8
42 focal hand dystonia 9.8
43 pain agnosia 9.8
44 acoustic neuroma 9.8
45 carotid stenosis 9.8
46 transient global amnesia 9.8
47 benign paroxysmal positional nystagmus 9.8
48 neuroma 9.8
49 toxic encephalopathy 9.8
50 movement disease 9.8

Graphical network of the top 20 diseases related to Whiplash:

Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 56)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Central Nervous System Depressants Phase 4,Phase 2,Not Applicable
2 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
3 Anesthetics Phase 4,Not Applicable
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
Ethanol Approved Phase 2 64-17-5 702
Ibuprofen Approved Phase 2 15687-27-1 3672
Amitriptyline Approved Phase 2 50-48-6 2160
Cyclobenzaprine Approved Phase 2 303-53-7 2895
10 Hydrocortisone hemisuccinate Phase 2
11 Anti-Inflammatory Agents Phase 2,Not Applicable
12 Hydrocortisone-17-butyrate Phase 2
13 Hydrocortisone 17-butyrate 21-propionate Phase 2
14 Analgesics Phase 2,Not Applicable
15 Antirheumatic Agents Phase 2,Not Applicable
16 Analgesics, Non-Narcotic Phase 2,Not Applicable
17 Anti-Inflammatory Agents, Non-Steroidal Phase 2,Not Applicable
18 Adrenergic Agents Phase 2
19 Amitriptyline, perphenazine drug combination Phase 2
20 Antidepressive Agents, Tricyclic Phase 2
21 Tranquilizing Agents Phase 2
22 Neurotransmitter Agents Phase 2
23 Psychotropic Drugs Phase 2
24 Cyclooxygenase Inhibitors Phase 2
25 Neurotransmitter Uptake Inhibitors Phase 2
26 Antidepressive Agents Phase 2
27 Neuromuscular Agents Phase 2
Mannitol Approved, Investigational Not Applicable 69-65-8 453 6251
Levobupivacaine Approved, Investigational Not Applicable 27262-47-1 92253
Triamcinolone Approved, Vet_approved Not Applicable 124-94-7 31307
Pyrantel Approved, Vet_approved Not Applicable 15686-83-6
Citalopram Approved 59729-33-8 2771
Norepinephrine Approved 51-41-2 439260
tannic acid Approved Not Applicable 1401-55-4
Benzocaine Approved, Investigational Not Applicable 94-09-7, 1994-09-7 2337
Imidacloprid Vet_approved Not Applicable 105827-78-9 86418
37 Pharmaceutical Solutions Not Applicable
38 Pyranoprofen Not Applicable
39 Vaccines Early Phase 1
40 Immunologic Factors Early Phase 1
41 Triamcinolone diacetate Not Applicable
42 triamcinolone acetonide Not Applicable
43 Triamcinolone hexacetonide Not Applicable
44 Pyrantel Pamoate Not Applicable
45 Muscarinic Antagonists
46 Serotonin Agents
47 Serotonin Uptake Inhibitors
48 Antiparkinson Agents
49 Cholinergic Agents
50 Cholinergic Antagonists

Interventional clinical trials:

(show top 50) (show all 57)
# Name Status NCT ID Phase Drugs
1 Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity Terminated NCT01255631 Phase 4
2 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder Withdrawn NCT02060734 Phase 4
3 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
4 University Health Network Whiplash Intervention Trial Completed NCT00546806 Phase 3
5 Preventing Chronic Whiplash Pain Completed NCT00021476 Phase 3
6 Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury Completed NCT00206271 Phase 3
7 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
8 Association Between Low Cortisol Levels and Whiplash Syndrome Unknown status NCT02090309 Phase 2 Hydrocortisone;normal saline 0.9%
9 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash? Completed NCT01512576 Phase 2
10 Acupuncture for Whiplash Associated Disorder Completed NCT01395511 Phase 2
11 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2 Cyclobenzaprine;Ibuprofen;Ibuprofen plus Cyclobenzaprine
12 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain Completed NCT01518530 Phase 2
13 Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders Unknown status NCT02251028 Not Applicable
14 Central Sensitization in Chronic Whiplash Patients Unknown status NCT03005691
15 Whiplash-associated Disorders - Needling Treatments Pilot Study Unknown status NCT01824810 Not Applicable
16 Is Chronic Whiplash-associated Pain of Neurogenic Origin? Unknown status NCT02692937 Not Applicable
17 East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders Unknown status NCT01369238 Not Applicable zaltoprofen
18 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Unknown status NCT01544075 Early Phase 1
19 Treatment of Whiplash Associated Disorders by APOS Kit Unknown status NCT00266981 Not Applicable
20 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
21 A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138 Not Applicable
22 Neuroscience Education on Osteoarthritis Unknown status NCT02246088 Not Applicable
23 RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain Unknown status NCT01743326 Not Applicable
24 Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study Unknown status NCT00510757
25 Clinical Effect Size of an Educational Intervention in the Home and Compliance on People Who Suffer From Stroke Unknown status NCT01980641 Not Applicable
26 Measuring the Impact of the French Version of the Whiplash Book Completed NCT03040245
27 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders Completed NCT01601912 Atomoxetine;Citalopram
28 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders Completed NCT01528579 Not Applicable
29 Manual Therapy to Treat Acute Whiplash Injury Completed NCT01825460 Not Applicable
30 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624 Not Applicable
31 Randomized WAD Study Completed NCT01994044 Not Applicable
32 Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain Completed NCT01431261 Not Applicable
33 Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033 Not Applicable
34 Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention. Completed NCT02625896 Not Applicable
35 Icing Effects on Neck Functions of the Boxers Completed NCT01203280 Not Applicable
36 Explain Pain in Fibromyalgia Patients Completed NCT02474875 Not Applicable
37 Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training Completed NCT02098005 Not Applicable
38 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143 Not Applicable
39 Concussion in Motor Vehicle Accidents: The Concussion Identification Index Completed NCT02858544
40 Why Does Acute Post Whiplash Injury Pain Transform Into Chronic Pain? Recruiting NCT02560675
41 Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders Recruiting NCT03664934 Not Applicable
42 Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting Recruiting NCT02570659 Not Applicable
43 Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders Recruiting NCT03239938 Not Applicable
44 Neck-specific Exercise in Chronic Whiplash Recruiting NCT03022812 Not Applicable
45 A Single Dry Needling Session of the Obliquus Capitis Inferior for the Altered Sensorimotor Function in People With Neck Pain Recruiting NCT03838224 Not Applicable
46 Modeling Post-traumatic Pain and Recovery: The SYMBIOME Longitudinal Cohort Study Recruiting NCT02711085
47 Postural Garment Versus Exercises for Women With Cervical Pain Recruiting NCT03560492 Not Applicable
48 Effectiveness of an Educational Video Following Acute Whiplash Trauma Active, not recruiting NCT01699334 Not Applicable
49 Changes of Pain Sensitivity During Rehabilitation of Patients Suffering From Whiplash Associated Disorders Active, not recruiting NCT03784196
50 A Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder Active, not recruiting NCT03729856 Not Applicable

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

Brain, Testes, Eye, Spinal Cord, Bone, Skin, Hypothalamus

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 1762)
# Title Authors Year
Instant reduction in postural sway during quiet standing by intraoral dental appliance in patients with Whiplash associated Disorders and non-trauma neck pain. ( 30384151 )
Agreement is very low between a clinical prediction rule and physiotherapist assessment for classifying the risk of poor recovery of individuals with acute whiplash injury. ( 30522090 )
Cervical rotator muscle activity with eye movement at different speeds is distorted in whiplash. ( 30609281 )
Physiotherapist-delivered stress inoculation training integrated with exercise versus physiotherapy exercise alone for acute whiplash-associated disorder (StressModex): a randomised controlled trial of a combined psychological/physical intervention. ( 30661011 )
Is a government-regulated rehabilitation guideline more effective than general practitioner education or preferred-provider rehabilitation in promoting recovery from acute whiplash-associated disorders? A pragmatic randomised controlled trial. ( 30679283 )
Pathophysiology behind prolonged whiplash associated disorders: study protocol for an experimental study. ( 30711003 )
Attachment insecurity as a vulnerability factor in the development of chronic whiplash associated disorder - A prospective cohort study. ( 30782355 )
Psychological Manifestations and Chronic Pain in Whiplash-Associated Disorder Mechanisms: The Whole Pie, Please. ( 30819055 )
Precollision Medical Diagnoses Predict Chronic Neck Pain Following Acute Whiplash Trauma. ( 30829733 )
Intramuscular fat is present in cervical multifidus but not soleus in patients with chronic whiplash associated disorders. ( 29795590 )
Biomechanics of coupled motion in the cervical spine during simulated whiplash in patients with pre-existing cervical or lumbar spinal fusion: A Finite Element Study. ( 29330341 )
Whiplash injury results in sustained impairments of cervical muscle function: A one-year prospective, controlled study. ( 29767228 )
Pregabalin versus placebo in targeting pro-nociceptive mechanisms to prevent chronic pain after whiplash injury in at-risk individuals - a feasibility study for a randomised controlled trial. ( 29343280 )
Anthropometric characteristics and traffic accident circumstances of patients with isolated whiplash injury in University Clinical Hospital Mostar. ( 29214988 )
Neck-specific exercise improves impaired interactions between ventral neck muscles in chronic whiplash: A randomized controlled ultrasound study. ( 29941911 )
Excessive Daytime Sleepiness and Injury of the Ascending Reticular Activating System Following Whiplash Injury. ( 29896079 )
Investigation of the Effect of Neck Muscle Active Force on Whiplash Injury of the Cervical Spine. ( 29849760 )
Evidence for Increased MRI Signal Intensity and Morphological Changes in the Brachial Plexus and Median Nerves of Patients With Chronic Arm and Neck Pain Following Whiplash Injury. ( 29690828 )
More whiplash weather in store for California. ( 29717236 )
Reciprocal associations of pain and post-traumatic stress symptoms after whiplash injury: A longitudinal, cross-lagged study. ( 29377453 )
Validity and test-retest reliability of the Dutch modified Perceived Deficits Questionnaire to examine cognitive symptoms in women with chronic whiplash, chronic idiopathic neck pain and fibromyalgia. ( 29383819 )
Lateral atlantoaxial joint meniscoid volume in individuals with whiplash associated disorder: A case-control study. ( 29153925 )
Pathology and Treatment of Traumatic Cervical Spine Syndrome: Whiplash Injury. ( 29682354 )
Information needs of patients with whiplash associated disorders: A Delphi study of patient beliefs. ( 29073494 )
Long-term follow-up of whiplash injuries reported to insurance companies: a cohort study on patient-reported outcomes and impact of financial compensation. ( 29429037 )
Is Delayed Surgery After Unsuccessful Conservative Treatment Beneficial for Spinal Cord Injury Following Whiplash? A Retrospective Study in Elderly Patients. ( 29729179 )
Superior outcomes following cervical fusion vs. multimodal rehabilitation in a subgroup of randomized Whiplash-Associated-Disorders (WAD) patients indicating somatic pain origin-Comparison of outcome assessments made by four examiners from different disciplines. ( 29794310 )
The Discrepancy between Subjective and Objective Measures of Convergence Insufficiency in Whiplash-Associated Disorder versus Control Participants. ( 29371010 )
A narrative review on cervical interventions in adults with chronic whiplash-associated disorder. ( 29719724 )
Can a Chronic BPPV With a History of Trauma be the Trigger of Symptoms in Vestibular Migraine, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and Whiplash Associated Disorders (WAD)? A Retrospective Cohort Study. ( 30303941 )
Swallow Syncope After Whiplash Neck Injury. ( 29658863 )
Correction: A narrative review on cervical interventions in adults with chronic whiplash-associated disorder. ( 30167322 )
Relationship between neck motion and self-reported pain in patients with whiplash associated disorders during the acute phase. ( 30218881 )
Physiotherapist-delivered Stress Inoculation Training for acute whiplash-associated disorders: A qualitative study of perceptions and experiences. ( 30218882 )
The effect of three exercise approaches on health-related quality of life, and factors associated with its improvement in chronic whiplash-associated disorders: analysis of a randomized controlled trial. ( 30225786 )
Acupuncture for treating whiplash-associated disorder: A systematic review and meta-analysis protocol. ( 30313054 )
Can cortisol levels predict the severity of acute whiplash-associated disorders? ( 30315329 )
Use of and attitudes to the role of medication for acute whiplash injury: A preliminary survey of emergency department doctors. ( 30317691 )
Trajectories of posttraumatic stress symptoms after whiplash: A prospective cohort study. ( 30318773 )
Whiplash Patients' Responses on the Impact of Events Scale-R - Congruent With Pain or PTSD Symptoms? ( 30371516 )
Relationship Between Psychosocial Factors and Pain in the Jaw and Neck Regions Shortly After Whiplash Trauma. ( 30371684 )
A core outcome set for clinical trials in whiplash-associated disorders (WAD): a study protocol. ( 30454057 )
Has the quality of physiotherapy care in patients with Whiplash-associated disorders (WAD) improved over time? A retrospective study using routinely collected data and quality indicators. ( 30519001 )
Medicine use during acute and chronic post-injury periods in whiplash injured individuals. ( 30531309 )
A 20-year prospective longitudinal MRI study on cervical spine after whiplash injury: Follow-up of a cross-sectional study. ( 30553607 )
Pre-collision Medical Diagnoses Predict Chronic Neck Pain Following Acute Whiplash-trauma. ( 30589659 )
A predictive model to analyze factors affecting the presence of mild whiplash-associated disorders in minor motor vehicle crashes based on the Korean In-Depth Accidents Study (KIDAS) Database. ( 30633556 )
Central Sensitization Is Modulated Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. A Double-Blind, Placebo-Controlled, Crossover Study. ( 28419379 )
Investigating the Fear Avoidance Model in People With Whiplash: The Association Between Fear of Movement and In Vivo Activity. ( 28591083 )
What information do patients need following a whiplash injury? The perspectives of patients and physiotherapists. ( 28637144 )

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
Show member pathways
13.29 CCL3 CCL4 CCL5 CCR5 IL16
Show member pathways
13.07 CCL3 CCL4 CCL5 CCR5 IL16
Show member pathways
Show member pathways
12.9 CCL3 CCL4 CCL5 CCR5 IL16
Show member pathways
12.63 CCL3 CCL4 CCL5 CCR5
Show member pathways
12.57 CCL3 CCL4 CCL5 CCR5
Show member pathways
11.88 CCL3 CCL4 CCL5 CCR5
Show member pathways
11.68 CCL3 CCL4 CCL5 IL16
Show member pathways
11.63 CCL3 CCL4 CCR5
10 11.35 CCL3 CCL4 CCL5
Show member pathways
11.32 CCL3 CCL4 CCL5 CCR5
12 11.23 CCL3 CCL4 CCL5
13 10.69 CCL3 CCL4 CCL5 IL16
14 10.66 CCL3 CCL4 CCL5 IL16
15 10.61 CCL3 CCL4 CCL5 CCR5

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CCL3 CCL4 CCL5 IL16 KNG1
2 extracellular space GO:0005615 9.02 CCL3 CCL4 CCL5 IL16 KNG1

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.91 CCL3 CCL4 CCL5 IL16
2 immune response GO:0006955 9.88 CCL3 CCL4 CCL5 CCR5 IL16
3 positive regulation of GTPase activity GO:0043547 9.84 CCL3 CCL4 CCL5
4 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.83 CCL3 CCL4 CCL5
5 MAPK cascade GO:0000165 9.82 CCL3 CCL5 CCR5
6 cell-cell signaling GO:0007267 9.81 CCL3 CCL4 CCL5 CCR5
7 calcium ion transport GO:0006816 9.8 CCL3 CCL5 CCR5
8 inflammatory response GO:0006954 9.8 CCL3 CCL4 CCL5 CCR5 KNG1
9 cellular response to tumor necrosis factor GO:0071356 9.79 CCL3 CCL4 CCL5
10 cellular response to interferon-gamma GO:0071346 9.76 CCL3 CCL4 CCL5
11 response to toxic substance GO:0009636 9.75 CCL3 CCL4 CCL5
12 cell chemotaxis GO:0060326 9.74 CCL3 CCL5 CCR5
13 neutrophil chemotaxis GO:0030593 9.72 CCL3 CCL4 CCL5
14 cytokine-mediated signaling pathway GO:0019221 9.72 CCL3 CCL4 CCL5 CCR5 IL16
15 cellular response to interleukin-1 GO:0071347 9.71 CCL3 CCL4 CCL5
16 cellular response to organic cyclic compound GO:0071407 9.67 CCL3 CCL5
17 monocyte chemotaxis GO:0002548 9.67 CCL3 CCL4 CCL5
18 positive chemotaxis GO:0050918 9.66 CCL3 CCL5
19 protein kinase B signaling GO:0043491 9.66 CCL3 CCL5
20 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 CCL3 CCL5
21 regulation of sensory perception of pain GO:0051930 9.65 CCL3 COMT
22 dendritic cell chemotaxis GO:0002407 9.64 CCL5 CCR5
23 positive regulation of calcium-mediated signaling GO:0050850 9.63 CCL3 CCL4
24 lymphocyte chemotaxis GO:0048247 9.63 CCL3 CCL4 CCL5
25 macrophage chemotaxis GO:0048246 9.61 CCL3 CCL5
26 positive regulation of calcium ion transport GO:0051928 9.61 CCL3 CCL4 CCL5
27 response to cholesterol GO:0070723 9.6 CCL3 CCR5
28 signaling GO:0023052 9.59 CCL3 CCR5
29 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.56 CCL3 CCR5
30 eosinophil chemotaxis GO:0048245 9.54 CCL3 CCL4 CCL5
31 chemokine-mediated signaling pathway GO:0070098 9.46 CCL3 CCL4 CCL5 CCR5
32 negative regulation by host of viral transcription GO:0043922 9.43 CCL3 CCL4 CCL5
33 negative regulation of macrophage apoptotic process GO:2000110 9.22 CCR5
34 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL3 CCL4 CCL5
35 chemotaxis GO:0006935 9.02 CCL3 CCL4 CCL5 CCR5 IL16
36 G protein-coupled receptor signaling pathway GO:0007186 10.02 CCL3 CCL4 CCL5 CCR5 KNG1

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.56 CCL3 CCL4 CCL5 IL16
2 chemokine activity GO:0008009 9.5 CCL3 CCL4 CCL5
3 chemoattractant activity GO:0042056 9.43 CCL3 CCL5
4 phosphatidylinositol phospholipase C activity GO:0004435 9.4 CCL5 CCR5
5 phospholipase activator activity GO:0016004 9.37 CCL3 CCL5
6 CCR chemokine receptor binding GO:0048020 9.33 CCL3 CCL4 CCL5
7 CCR5 chemokine receptor binding GO:0031730 9.13 CCL3 CCL4 CCL5
8 CCR1 chemokine receptor binding GO:0031726 8.8 CCL3 CCL4 CCL5

Sources for Whiplash

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
33 HPO
34 ICD10
35 ICD10 via Orphanet
39 LifeMap
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
56 Novoseek
59 OMIM via Orphanet
63 PubMed
71 SNOMED-CT via Orphanet
73 Tocris
75 UMLS via Orphanet
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