Aliases & Classifications for Whiplash

MalaCards integrated aliases for Whiplash:

Name: Whiplash 53

Summaries for Whiplash

NINDS : 53 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to radiculopathy and allergic hypersensitivity disease. An important gene associated with Whiplash is CCL3 (C-C Motif Chemokine Ligand 3), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Pharmaceutical Solutions and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and eye.

Wikipedia : 74 Whiplash is a 2014 American drama film written and directed by Damien Chazelle. It depicts the... more...

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
# Related Disease Score Top Affiliating Genes
1 radiculopathy 30.4 CCL5 CCL4 CCL3
2 allergic hypersensitivity disease 30.3 KNG1 CCL5 CCL3
3 paine syndrome 29.8 KNG1 COMT
4 multiple sclerosis 28.5 IL16 CCR5 CCL5 CCL4 CCL3
5 systemic lupus erythematosus 28.4 IL16 CCR5 CCL5 CCL4 CCL3
6 chronic pain 10.9
7 headache 10.7
8 head injury 10.6
9 fibromyalgia 10.5
10 back pain 10.5
11 acute stress disorder 10.4
12 post-traumatic stress disorder 10.4
13 migraine with or without aura 1 10.3
14 spinal cord injury 10.3
15 traumatic brain injury 10.3
16 amnestic disorder 10.3
17 spondylosis 10.3
18 thoracic outlet syndrome 10.3
19 chronic fatigue syndrome 10.3
20 brain injury 10.3
21 neurotic disorder 10.2
22 allergic encephalomyelitis 10.2 CCL5 CCL3
23 respiratory syncytial virus infectious disease 10.2 CCL5 CCL3
24 latex allergy 10.2 CCL4 CCL3
25 african tick-bite fever 10.2 CCL5 CCL3
26 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
27 temporomandibular joint anomaly 10.2
28 chronic eosinophilic pneumonia 10.2 CCL5 CCL3
29 submandibular gland cancer 10.2 CCR5 CCL3
30 west nile virus infection 10.2 CCR5 CCL5
31 chronic inflammatory demyelinating polyradiculoneuropathy 10.2 CCL5 CCL4
32 mesangial proliferative glomerulonephritis 10.2 CCR5 CCL3
33 somatization disorder 10.2
34 poliomyelitis 10.2
35 pathologic nystagmus 10.2
36 polyradiculoneuropathy 10.2 CCL5 CCL4
37 proliferative glomerulonephritis 10.2 CCR5 CCL3
38 mast-cell leukemia 10.1 CCL5 CCL3
39 pulmonary eosinophilia 10.1 CCL5 CCL3
40 oral lichen planus 10.1 CCR5 CCL5
41 cytomegalovirus infection 10.1 CCL5 CCL3
42 complex regional pain syndrome 10.1 CCL4 CCL3
43 genital herpes 10.1 CCR5 CCL5
44 carpal tunnel syndrome 10.1
45 exanthem 10.1
46 pain agnosia 10.1
47 plica syndrome 10.1
48 benign paroxysmal positional nystagmus 10.1
49 synovitis 10.1
50 dermatitis 10.1

Graphical network of the top 20 diseases related to Whiplash:

Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 57)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 4
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2, Phase 3 1177-87-3
Dexamethasone Approved, Investigational, Vet_approved Phase 2, Phase 3 50-02-2 5743
4 BB 1101 Phase 2, Phase 3
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
Amitriptyline Approved Phase 2 50-48-6 2160
Cyclobenzaprine Approved Phase 2 303-53-7 2895
Ibuprofen Approved Phase 2 15687-27-1 3672
Tropisetron Approved, Investigational Phase 2 89565-68-4, 105826-92-4 5595
11 Hydrocortisone 17-butyrate 21-propionate Phase 2
12 Hydrocortisone hemisuccinate Phase 2
13 Antirheumatic Agents Phase 2
14 Anti-Inflammatory Agents Phase 2
15 Anti-Inflammatory Agents, Non-Steroidal Phase 2
16 Antidepressive Agents Phase 2
17 Adrenergic Agents Phase 2
18 Psychotropic Drugs Phase 2
19 Neurotransmitter Agents Phase 2
20 Cyclooxygenase Inhibitors Phase 2
21 Amitriptyline, perphenazine drug combination Phase 2
22 Antidepressive Agents, Tricyclic Phase 2
23 Gastrointestinal Agents Phase 2
24 Antiemetics Phase 2
25 Serotonin 5-HT3 Receptor Antagonists Phase 2
Serotonin Investigational, Nutraceutical Phase 2 50-67-9 5202
Mannitol Approved, Investigational 69-65-8 6251 453
Levobupivacaine Approved, Investigational 27262-47-1 92253
Triamcinolone Approved, Vet_approved 124-94-7 31307
Pyrantel Approved, Vet_approved 15686-83-6
Citalopram Approved 59729-33-8 2771
Norepinephrine Approved 51-41-2 439260
Ethanol Approved 64-17-5 702
Nicotine Approved 54-11-5 942 89594
Caffeine Approved 58-08-2 2519
tannic acid Approved 1401-55-4
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
Dimenhydrinate Approved 523-87-5 441281
Imidacloprid Vet_approved 105827-78-9 86418
40 Pyranoprofen
41 Vaccines Early Phase 1
42 Immunologic Factors Early Phase 1
43 triamcinolone acetonide
44 Triamcinolone hexacetonide
45 Triamcinolone diacetate
46 Pyrantel Pamoate
47 Parasympatholytics
48 Cholinergic Agents
49 Antiparkinson Agents
50 Serotonin Uptake Inhibitors

Interventional clinical trials:

(show top 50) (show all 77)
# Name Status NCT ID Phase Drugs
1 Prospective Pilot Study: Prolotherapy For The Treatment Of Patients With Partial Rotator Cuff Tears Not yet recruiting NCT04062838 Phase 4 Dextrose 50
2 Use of Pulsed Electromagnetic Fields in Reducing Arm and Shoulder Complaints in Breast Cancer Patients After Lymph Node Dissection Terminated NCT01255631 Phase 4
3 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated disorder-a Randomized Controlled Trial Withdrawn NCT02060734 Phase 4
4 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
5 A Randomized Early Intervention Study Comparing the Effect of Stiff Neck Collar, “Act-as-Usual” and Active Mobilisation on the One Year Outcome Following Whiplash Injury. Completed NCT00206271 Phase 3
6 The University Health Network Whiplash Intervention Trial: A Randomized Controlled Trial of the Effectiveness and Cost-effectiveness of Three Programs of Care for the Treatment of Whiplash-associated Disorders Completed NCT00546806 Phase 3
7 Preventing Chronic Whiplash Pain: Biobehavioral Approach Completed NCT00021476 Phase 3
8 A Pilot Study Comparing Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) as a Treatment for Cervical Facetogenic Pain Not yet recruiting NCT04392999 Phase 2, Phase 3 Intraarticular platelet rich plasma cervical facet injection;Corticosteroid injection
9 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
10 The Association Between Low Cortisol Level and Whiplash Syndrome and the Effect of a Single Hydrocortisone Injection on Neck Symptoms Among Motor Vehicle Accident Victims: a Randomized Placebo Controlled Double Blinded Study Unknown status NCT02090309 Phase 2 Hydrocortisone;normal saline 0.9%
11 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash Associated Disorders? A Randomized Cross-over Trial Completed NCT01512576 Phase 2
12 Acupuncture for Whiplash Associated Disorder: a Randomised, Waiting-list Controlled, Open-label, Parallel-group Pilot Trial Completed NCT01395511 Phase 2
13 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2 Cyclobenzaprine;Ibuprofen;Ibuprofen plus Cyclobenzaprine
14 Modulation of Central Hypersensitivity in Chronic Musculoskeletal Pain by Intravenous Tropisetron Completed NCT00889499 Phase 2 Tropisetron 2 mg;Tropisetron 5mg;Placebo
15 A Randomized Controlled Trial Which Compare the Effectiveness of an APOS Kit With Short Waves Therapy for Treating Whiplash Associated Disorders Unknown status NCT00266981
16 Clinical Research on the Efficacy of East-West Collaborative Medicine Using Bee-Venom Acupuncture Therapy on Whiplash-Associated Disorders After Traffic Collisions; A Randomized, Controlled, Parallel Trial Unknown status NCT01369238 zaltoprofen
17 Value-based Cognitive Behavioural Therapy for the Prevention of Chronic Whiplash Associated Disorders: A Randomized Controlled Trial Unknown status NCT02251028
18 A Randomized Controlled Trial Evaluating the Effect of an Information Video in a Acute Whiplash Population Unknown status NCT02570659
19 Central Sensitization in Chronic Whiplash Patients: Metabolite Concentrations in the Anterior Cingulate Cortex and Periacueductal Gray Matter Unknown status NCT03005691
20 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Associated Disorders : a Double-blind Randomised Controlled Trial Unknown status NCT01544075 Early Phase 1
21 A Pilot Case Randomized Control Study Analysing the Effectiveness of 3 Needling Techniques: Intramuscular Stimulation, Neural Prolotherapy, and Myofascial Release in the Treatment of Chronic Whiplash Associated Disorder. Unknown status NCT01824810
22 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
23 Advantages of the Paramedian Approach for Cervical Epidural Steroid Injections: A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138
24 Effect of Neuroscience Education on Subjects With Chronic Knee Pain Related to Osteoarthritis : a Randomized Controlled Trial Unknown status NCT02246088
25 Percutaneous Radiofrequency Denervation of the Cervical Facet Joints Compared With Cervical Medial Branch Block of the Facet Joints for Patients With Chronic Degenerative Neck Pain : A Prospective Randomized Clinical Study Unknown status NCT01743326
26 Pain Sensitization and the Risk of Poor Outcome Following Physiotherapy for Knee Osteoarthritis: A Protocol for a Prospective Cohort Study Unknown status NCT02310945
27 Efficacy of the Use of Dry Needling in Conventional Non-invasive Treatment of Acute and Subacute Whiplash Completed NCT03502928
28 Measuring the Impact of the French Version of the Whiplash Book on Both Treatment Approach and Fears and Beliefs Among Emergency Physicians Completed NCT03040245
29 Effectiveness of an Educational Video Following Acute Whiplash Trauma: A Randomized Controlled Trial Completed NCT01699334
30 Short-Term Effects of a Manual Therapy Protocol Completed NCT01825460
31 Neck Exercises, Physical and Cognitive Behavioural Graded Activity as a Treatment for Adult Whiplash Patients With Chronic Neck Pain Completed NCT01431261
32 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624
33 Treating Selected Chronic WAD Patients: Cervical Fusion or Multidimensional Rehabilitation. A Randomized Study Completed NCT01994044
34 Icing Effects on Neck Functions of the Boxers Completed NCT01203280
35 The Efficacy and Safety of Trapezius MSAT on Inpatients With Acute Whiplash Injury Caused by Traffic Accidents: A Randomized Controlled Trials Completed NCT04113824
36 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders: a Prospective Randomized Study Completed NCT01528579
37 Clinical and Biological Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033
38 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders: a Randomized Controlled Clinical Trial for the Treatment of Central Sensitization Completed NCT01601912 Atomoxetine;Citalopram
39 Is Chronic Whiplash-associated Pain of Neurogenic Origin? A Study Protocol of a Randomized Controlled Trial Comparing Neurolysis of Peripheral Nerves With Traditional Neck-specific Exercise Completed NCT02692937
40 The Analysis for Factors Affecting Termination of Treatment and Treatment Satisfaction of Korean Medicine in Traffic Accident Injury Patients: A Retrospective Study With Survey Completed NCT04167930
41 Evaluation of a Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder: a Multiple-baseline, Single Case Experimental Study Completed NCT03729856
42 Explain Pain in Fibromyalgia Patients Completed NCT02474875
43 Application of High Frequency Electrical Currents: Effects on Mechanical Threshold, Tactile Threshold and Evoked Potentials in Healthy Subjects. Completed NCT02837458
44 The Effectiveness of Two Training Protocols When Managing Chronic Cervical Pain: Controlled Randomized Clinical Trial. Completed NCT02225873
45 Effects of Kinesio Taping in Patients With Somatosensory Tinnitus: A Randomized Controlled Trial Completed NCT03782220
46 Prognostic Value of Measures of Central Hypersensitivity in Patients With Low Back Pain Completed NCT00892411
47 Effectiveness of an Eye-Cervical Re-education Program (ECRP) to Decrease Pain and Increase Mobility in the Cervical Area Compared to a Combined Physiotherapy Protocol (CPP) in Patients With Chronic Neck Pain Symptoms. Completed NCT03197285
48 Effect of the Kinesio Taping in Patients With Fibromyalgia. Completed NCT02763332
49 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143
50 Effects of a Single Dry Needling Session of the Obliquus Capitis Inferior on the Altered Sensorimotor Function in People With Neck Pain: a Random Control Trial Completed NCT03838224

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

Testes, Brain, Eye, Spinal Cord, Bone, Cortex, Breast

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 3039)
# Title Authors PMID Year
Extended overview of the longitudinal pain-depression association: A comparison of six cohorts treated for specific chronic pain conditions. 61
32560947 2020
Estimating the number of traffic crash-related cervical spine injuries in the United States; An analysis and comparison of national crash and hospital data. 61
32413544 2020
Defining Recovery in Chronic Whiplash: A Qualitative Study. 61
32217847 2020
Jaw-neck motor function in the acute stage after whiplash trauma. 61
32306432 2020
Small fibre pathology in chronic whiplash-associated disorder: A cross-sectional study. 61
32096260 2020
Spinal cord injury is not a feature of chronic whiplash-associated disorder: a magnetic resonance spectroscopy study. 61
32303835 2020
Whiplash-Associated Dysphagia: Considerations of Potential Incidence and Mechanisms. 61
31377863 2020
Brain Network Disruption in Whiplash. 61
32499250 2020
Retrospective analysis of the incidence of trauma in patients with temporomandibular disorders. 61
32575165 2020
Effectiveness of Implementation Strategies to Improve Adherence of Physical Therapist Treatment Choices to Clinical Practice Guidelines for Musculoskeletal Conditions: Systematic Review. 61
32488264 2020
Whiplash-Associated Dysphagia and Dysphonia: A Scoping Review. 61
32445061 2020
Exercise Induced Hypoalgesia is Impaired in Chronic Whiplash Associated Disorders (WAD) with Both Aerobic and Isometric Exercise. 61
32433074 2020
Neck pain and headache after whiplash injury: a systematic review and meta-analysis. 61
31977938 2020
Exploring the relationship between chronic pain and cortisol levels in subjects with osteoarthritis: results from a systematic review of the literature. 61
32156623 2020
Does Motor Cortex Engagement During Movement Preparation Differentially Inhibit Nociceptive Processing in Patients with Chronic Whiplash Associated Disorders, Chronic Fatigue Syndrome and Healthy Controls? An Experimental Study. 61
32443565 2020
Letter to the Editor concerning "The role of non-rigid cervical collar in pain relief and functional restoration after whiplash injury: a systematic review and a pooled analysis of randomized controlled trials" by Ricciardi L, et al. (Eur Spine J; [2019] 28:1821-1828). 61
32180023 2020
Answer to the letter to the editor of Christensen S et al. concerning "The role of non-rigid cervical collar in pain relief and functional restoration after whiplash injury-a systematic review and a pooled analysis of randomized controlled trials" by Ricciardi L et al. (Eur Spine J; [2019] 28:1821-1828). 61
32193625 2020
Age-related changes to the craniocervical ligaments in asymptomatic subjects: a prospective MR study. 61
31980925 2020
Pain Sensitivity Modifies Risk of Injury-Related Temporomandibular Disorder. 61
32197057 2020
Does Overall Cervical Spine Pathology Relate to the Clinical Heterogeneity of Chronic Whiplash? 61
31285071 2020
Processing of Laser-Evoked Potentials in Patients with Chronic Whiplash-Associated Disorders, Chronic Fatigue Syndrome, and Healthy Controls: A Case-Control Study. 61
32289826 2020
Can cortisol levels predict the severity of acute whiplash-associated disorders? 61
30315329 2020
A pilot study on the evaluation of eye, head, and trunk coordination in subjects with chronic whiplash during a target-tracking task - A driving context approach. 61
32217270 2020
Optimization of Female Head-Neck Model with Active Reflexive Cervical Muscles in Low Severity Rear Impact Collisions. 61
32333133 2020
Road traffic whiplash injury in the elderly: Clinical and video-nystagmographic features. 61
32345445 2020
Intervention with an educational video after a whiplash trauma - a randomised controlled clinical trial. 61
31747385 2020
Neck-specific exercise for radiating pain and neurological deficits in chronic whiplash, a 1-year follow-up of a randomised clinical trial. 61
32317700 2020
A Qualitative Comparison of Reassurance Approaches Used by Physical Therapists to Address Fears and Concerns of Patients With Nonspecific Neck Pain and Whiplash Associated Disorders: An Online Survey. 61
32280971 2020
Evaluating the Effects of a Novel Neuromuscular Neck Training Device on Multiplanar Static and Dynamic Neck Strength: A Pilot Study. 61
30946260 2020
Characterizing the Mechanical Properties of Ectopic Axonal Receptive Fields in Inflamed Nerves and Following Axonal Transport Disruption. 61
31874241 2020
Can measuring passive neck muscle stiffness in whiplash injury patients help detect false whiplash claims? 61
32189119 2020
Medical and allied health service use during acute and chronic post-injury periods in whiplash injured individuals. 61
32228573 2020
Diagnostic Accuracy of Videofluoroscopy for Symptomatic Cervical Spine Injury Following Whiplash Trauma. 61
32150926 2020
Non-whiplash soft tissue injuries following low-velocity impact collisions: A retrospective analysis. 61
31859584 2020
Recovery despite everyday pain: Women's experiences of living with whiplash-associated disorder. 61
31917514 2020
Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD. 61
32094442 2020
Acupuncture for whiplash-associated disorder following road traffic collision: a physiotherapy service evaluation. 61
32026700 2020
An analysis of whiplash injury outcomes in an Irish population: a retrospective fifteen-year study of a spine surgeon's experience. 61
31119531 2020
The Course of Orofacial Pain and Jaw Disability After Whiplash Trauma: A 2-year Prospective Study. 61
31513116 2020
The significance of cervical sagittal alignment for nonrecovery after whiplash injury. 61
32058085 2020
There's Nothing Broken. You've Had a Whiplash, That's It: A Qualitative Study of Comorbid Posttraumatic Stress Disorder and Whiplash Associated Disorders. 61
32101297 2020
Thresholds for the assessment of inflicted head injury by shaking trauma in infants: a systematic review. 61
31785511 2020
Biomechanical contribution of the alar ligaments to upper cervical stability. 61
31813563 2020
Cervical Muscle Tenderness in Temporomandibular Disorders and Its Associations with Diagnosis, Disease-Related Outcomes, and Comorbid Pain Conditions. 61
31465035 2020
A comparison of anti-whiplash seats during low/moderate speed rear-end collisions. 61
32027520 2020
Dissection of the V3-V4 due to whiplash injury: description of a non-fatal case. 61
31850477 2020
Muscle fat infiltration following whiplash: A computed tomography and magnetic resonance imaging comparison. 61
32484835 2020
Associations between the injustice experience questionnaire and treatment term in patients with acute Whiplash-associated disorder in Japan: Comparison with Canadian data. 61
32282836 2020
Measuring the impact of the French version of The Whiplash Book on both treatment approach and fear-avoidance beliefs among emergency physicians. A cluster randomized controlled trial. 61
32187610 2020
Relationships Between Context, Process, and Outcome Indicators to Assess Quality of Physiotherapy Care in Patients with Whiplash-Associated Disorders: Applying Donabedian's Model of Care. 61
32184572 2020

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
Show member pathways
13.26 IL16 CCR5 CCL5 CCL4 CCL3
Show member pathways
13.02 IL16 CCR5 CCL5 CCL4 CCL3
Show member pathways
12.91 IL16 CCR5 CCL5 CCL4 CCL3
Show member pathways
12.79 IL16 CCR5 CCL5 CCL4 CCL3
Show member pathways
12.68 KNG1 CCL5 CCL4 CCL3
Show member pathways
12.55 CCR5 CCL5 CCL4 CCL3
Show member pathways
12.49 CCR5 CCL5 CCL4 CCL3
Show member pathways
11.59 CCR5 CCL5 CCL4 CCL3
Show member pathways
11.49 CCR5 CCL4 CCL3
10 11.13 CCL5 CCL4 CCL3
Show member pathways
11.07 CCL4 CCL3
12 10.61 CCR5 CCL5 CCL4 CCL3
13 10.57 IL16 CCL5 CCL4 CCL3

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell GO:0005623 9.26 KNG1 CCR5 CCL5 CCL3
2 extracellular space GO:0005615 9.02 KNG1 IL16 CCL5 CCL4 CCL3

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.06 IL16 CCR5 CCL5 CCL4 CCL3
2 G protein-coupled receptor signaling pathway GO:0007186 10.02 KNG1 CCR5 CCL5 CCL4 CCL3
3 immune response GO:0006955 9.85 IL16 CCR5 CCL5 CCL4 CCL3
4 positive regulation of GTPase activity GO:0043547 9.84 CCL5 CCL4 CCL3
5 MAPK cascade GO:0000165 9.83 CCR5 CCL5 CCL3
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.81 CCL5 CCL4 CCL3
7 cell-cell signaling GO:0007267 9.81 CCR5 CCL5 CCL4 CCL3
8 calcium ion transport GO:0006816 9.8 CCR5 CCL5 CCL3
9 cellular response to tumor necrosis factor GO:0071356 9.79 CCL5 CCL4 CCL3
10 inflammatory response GO:0006954 9.77 KNG1 CCR5 CCL5 CCL4 CCL3
11 cellular response to interferon-gamma GO:0071346 9.76 CCL5 CCL4 CCL3
12 response to toxic substance GO:0009636 9.75 CCL5 CCL4 CCL3
13 cell chemotaxis GO:0060326 9.73 CCR5 CCL5 CCL3
14 cellular response to interleukin-1 GO:0071347 9.72 CCL5 CCL4 CCL3
15 cytokine-mediated signaling pathway GO:0019221 9.72 IL16 CCR5 CCL5 CCL4 CCL3
16 neutrophil chemotaxis GO:0030593 9.71 CCL5 CCL4 CCL3
17 cellular response to organic cyclic compound GO:0071407 9.67 CCL5 CCL3
18 monocyte chemotaxis GO:0002548 9.67 CCL5 CCL4 CCL3
19 positive chemotaxis GO:0050918 9.66 CCL5 CCL3
20 protein kinase B signaling GO:0043491 9.65 CCL5 CCL3
21 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 CCL5 CCL3
22 lymphocyte chemotaxis GO:0048247 9.65 CCL5 CCL4 CCL3
23 regulation of sensory perception of pain GO:0051930 9.64 COMT CCL3
24 positive regulation of calcium-mediated signaling GO:0050850 9.63 CCL4 CCL3
25 dendritic cell chemotaxis GO:0002407 9.63 CCR5 CCL5
26 macrophage chemotaxis GO:0048246 9.61 CCL5 CCL3
27 positive regulation of calcium ion transport GO:0051928 9.61 CCL5 CCL4 CCL3
28 response to cholesterol GO:0070723 9.6 CCR5 CCL3
29 signaling GO:0023052 9.59 CCR5 CCL3
30 eosinophil chemotaxis GO:0048245 9.58 CCL5 CCL4 CCL3
31 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.57 CCR5 CCL3
32 negative regulation of macrophage apoptotic process GO:2000110 9.52 CCR5 CCL5
33 chemokine-mediated signaling pathway GO:0070098 9.46 CCR5 CCL5 CCL4 CCL3
34 negative regulation by host of viral transcription GO:0043922 9.43 CCL5 CCL4 CCL3
35 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL5 CCL4 CCL3
36 chemotaxis GO:0006935 9.02 IL16 CCR5 CCL5 CCL4 CCL3

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.62 IL16 CCL5 CCL4 CCL3
2 chemoattractant activity GO:0042056 9.43 CCL5 CCL3
3 chemokine activity GO:0008009 9.43 CCL5 CCL4 CCL3
4 phosphatidylinositol phospholipase C activity GO:0004435 9.4 CCR5 CCL5
5 phospholipase activator activity GO:0016004 9.37 CCL5 CCL3
6 CCR chemokine receptor binding GO:0048020 9.33 CCL5 CCL4 CCL3
7 CCR5 chemokine receptor binding GO:0031730 9.13 CCL5 CCL4 CCL3
8 CCR1 chemokine receptor binding GO:0031726 8.8 CCL5 CCL4 CCL3

Sources for Whiplash

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
Loading form....