Aliases & Classifications for Whiplash

MalaCards integrated aliases for Whiplash:

Name: Whiplash 54

Summaries for Whiplash

NINDS : 54 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to pain - chronic and headache. An important gene associated with Whiplash is CCL5 (C-C Motif Chemokine Ligand 5), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Central Nervous System Depressants and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and brain.

Wikipedia : 76 Whiplash is a 2014 American drama film written and directed by Damien Chazelle. It depicts the... more...

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 pain - chronic 10.5
2 headache 10.4
3 depression 10.4
4 fibromyalgia 10.3
5 anxiety 10.2
6 thoracic outlet syndrome 10.1
7 mycetoma 10.1 CCL5 COMT
8 oral lichen planus 10.1 CCL5 CCR5
9 yellow fever 10.1 CCL5 CCR5
10 pulmonary sarcoidosis 10.1 CCL5 CCR5
11 autoimmune disease of central nervous system 10.1 CCL5 CCR5
12 omsk hemorrhagic fever 10.1 CCL4 CCL5
13 autoimmune disease of the nervous system 10.1 CCL5 CCR5
14 acute cervicitis 10.1 CCL4 CCL5
15 inclusion conjunctivitis 10.1 CCL5 IL16
16 brain injury 10.1
17 spinal cord injury 10.1
18 traumatic brain injury 10.1
19 radiculopathy 10.1
20 respiratory syncytial virus infectious disease 10.0 CCL3 CCL5
21 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.0 CCL4 CCR5
22 cytomegalovirus infection 9.9 CCL3 CCL5
23 bronchiolitis 9.9 CCL3 CCL5
24 necatoriasis 9.9 CCL3 CCL4
25 trypanosomiasis 9.9 CCL3 CCL5
26 night blindness, congenital stationary, type 1a 9.9 CCL3 CCL4
27 dermatitis, atopic 9.9 CCL4 CCL5 IL16
28 acquired immunodeficiency syndrome 9.9 CCL3 CCR5
29 orofacial granulomatosis 9.9 CCL3 CCL5 CCR5
30 proteasome-associated autoinflammatory syndrome 1 9.9 CCL3 CCL5
31 carpal tunnel syndrome 9.8
32 migraine with or without aura 1 9.8
33 vertigo, benign recurrent 9.8
34 body mass index quantitative trait locus 1 9.8
35 mononeuropathy of the median nerve, mild 9.8
36 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8
37 joint disorders 9.8
38 focal hand dystonia 9.8
39 acoustic neuroma 9.8
40 carotid stenosis 9.8
41 transient global amnesia 9.8
42 benign paroxysmal positional nystagmus 9.8
43 neuroma 9.8
44 post-traumatic stress disorder 9.8
45 dermatitis 9.8
46 toxic encephalopathy 9.8
47 neurotic disorder 9.8
48 dystonia 9.8
49 chronic fatigue syndrome 9.8
50 carotid artery dissection 9.8

Graphical network of the top 20 diseases related to Whiplash:



Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Central Nervous System Depressants Phase 4,Phase 2,Not Applicable
2 Anesthetics Phase 4,Not Applicable
3 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
4
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
5
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
6
Ethanol Approved Phase 2 64-17-5 702
7
Amitriptyline Approved Phase 2 50-48-6 2160
8
Ibuprofen Approved Phase 2 15687-27-1 3672
9
Cyclobenzaprine Approved Phase 2 303-53-7 2895
10 Hydrocortisone 17-butyrate 21-propionate Phase 2
11 Hydrocortisone-17-butyrate Phase 2
12 Anti-Inflammatory Agents Phase 2,Not Applicable
13 Cortisol succinate Phase 2
14 Analgesics Phase 2,Not Applicable
15 Analgesics, Non-Narcotic Phase 2,Not Applicable
16 Anti-Inflammatory Agents, Non-Steroidal Phase 2,Not Applicable
17 Antirheumatic Agents Phase 2,Not Applicable
18 Neuromuscular Agents Phase 2
19 Psychotropic Drugs Phase 2
20 Amitriptyline, perphenazine drug combination Phase 2
21 Neurotransmitter Uptake Inhibitors Phase 2
22 Antidepressive Agents Phase 2
23 Adrenergic Agents Phase 2
24 Neurotransmitter Agents Phase 2
25 Tranquilizing Agents Phase 2
26 Cyclooxygenase Inhibitors Phase 2
27 Antidepressive Agents, Tricyclic Phase 2
28
Mannitol Approved, Investigational Not Applicable 69-65-8 453 6251
29
Triamcinolone Approved, Vet_approved Not Applicable 124-94-7 31307
30
Levobupivacaine Approved, Investigational Not Applicable 27262-47-1 92253
31
Pyrantel Approved, Vet_approved Not Applicable 15686-83-6
32
Norepinephrine Approved 51-41-2 439260
33
Citalopram Approved 59729-33-8 2771
34
Imidacloprid Vet_approved Not Applicable 105827-78-9 86418
35 Pharmaceutical Solutions Not Applicable
36 Pyranoprofen Not Applicable
37 Immunologic Factors Early Phase 1
38 Vaccines Early Phase 1
39 triamcinolone acetonide Not Applicable
40 Triamcinolone diacetate Not Applicable
41 Triamcinolone hexacetonide Not Applicable
42 Pyrantel Pamoate Not Applicable
43 Cholinergic Agents
44 Antiparkinson Agents
45 Antidepressive Agents, Second-Generation
46 Cholinergic Antagonists
47 Muscarinic Antagonists
48 Autonomic Agents
49 Serotonin Uptake Inhibitors
50 Atomoxetine Hydrochloride

Interventional clinical trials:

(show top 50) (show all 56)
# Name Status NCT ID Phase Drugs
1 Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity Terminated NCT01255631 Phase 4
2 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder Withdrawn NCT02060734 Phase 4
3 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
4 University Health Network Whiplash Intervention Trial Completed NCT00546806 Phase 3
5 Preventing Chronic Whiplash Pain Completed NCT00021476 Phase 3
6 Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury Completed NCT00206271 Phase 3
7 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
8 Association Between Low Cortisol Levels and Whiplash Syndrome Unknown status NCT02090309 Phase 2 Hydrocortisone;normal saline 0.9%
9 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash? Completed NCT01512576 Phase 2
10 Acupuncture for Whiplash Associated Disorder Completed NCT01395511 Phase 2
11 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2 Cyclobenzaprine;Ibuprofen;Ibuprofen plus Cyclobenzaprine
12 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain Completed NCT01518530 Phase 2
13 Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders Unknown status NCT02251028 Not Applicable
14 Central Sensitization in Chronic Whiplash Patients Unknown status NCT03005691
15 Whiplash-associated Disorders - Needling Treatments Pilot Study Unknown status NCT01824810 Not Applicable
16 Is Chronic Whiplash-associated Pain of Neurogenic Origin? Unknown status NCT02692937 Not Applicable
17 East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders Unknown status NCT01369238 Not Applicable zaltoprofen
18 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Unknown status NCT01544075 Early Phase 1
19 Treatment of Whiplash Associated Disorders by APOS Kit Unknown status NCT00266981 Not Applicable
20 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
21 A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138 Not Applicable
22 Neuroscience Education on Osteoarthritis Unknown status NCT02246088 Not Applicable
23 RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain Unknown status NCT01743326 Not Applicable
24 Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study Unknown status NCT00510757
25 Measuring the Impact of the French Version of the Whiplash Book Completed NCT03040245
26 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders Completed NCT01601912 Atomoxetine;Citalopram
27 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders Completed NCT01528579 Not Applicable
28 Manual Therapy to Treat Acute Whiplash Injury Completed NCT01825460 Not Applicable
29 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624 Not Applicable
30 Randomized WAD Study Completed NCT01994044 Not Applicable
31 Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain Completed NCT01431261 Not Applicable
32 Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033 Not Applicable
33 Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention. Completed NCT02625896 Not Applicable
34 Icing Effects on Neck Functions of the Boxers Completed NCT01203280 Not Applicable
35 Explain Pain in Fibromyalgia Patients Completed NCT02474875 Not Applicable
36 Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training Completed NCT02098005 Not Applicable
37 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143 Not Applicable
38 Concussion in Motor Vehicle Accidents: The Concussion Identification Index Completed NCT02858544
39 Why Does Acute Post Whiplash Injury Pain Transform Into Chronic Pain? Recruiting NCT02560675
40 Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders Recruiting NCT03664934 Not Applicable
41 Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting Recruiting NCT02570659 Not Applicable
42 Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders Recruiting NCT03239938 Not Applicable
43 Neck-specific Exercise in Chronic Whiplash Recruiting NCT03022812 Not Applicable
44 Modeling Post-traumatic Pain and Recovery: The SYMBIOME Longitudinal Cohort Study Recruiting NCT02711085
45 Postural Garment Versus Exercises for Women With Cervical Pain Recruiting NCT03560492 Not Applicable
46 Clinical Effect Size of an Educational Intervention in the Home and Compliance on People Who Suffer From Stroke Recruiting NCT01980641 Not Applicable
47 Effectiveness of an Educational Video Following Acute Whiplash Trauma Active, not recruiting NCT01699334 Not Applicable
48 Changes of Pain Sensitivity During Rehabilitation of Patients Suffering From Whiplash Associated Disorders Active, not recruiting NCT03784196
49 A Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder Active, not recruiting NCT03729856 Not Applicable
50 Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries Active, not recruiting NCT02157038 Early Phase 1

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

41
Eye, Testes, Brain, Spinal Cord, Bone, Lymph Node, Cortex

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 1017)
# Title Authors Year
1
Instant reduction in postural sway during quiet standing by intraoral dental appliance in patients with Whiplash associated Disorders and non-trauma neck pain. ( 30384151 )
2019
2
Intramuscular fat is present in cervical multifidus but not soleus in patients with chronic whiplash associated disorders. ( 29795590 )
2018
3
Biomechanics of coupled motion in the cervical spine during simulated whiplash in patients with pre-existing cervical or lumbar spinal fusion: A Finite Element Study. ( 29330341 )
2018
4
Whiplash injury results in sustained impairments of cervical muscle function: A one-year prospective, controlled study. ( 29767228 )
2018
5
Pregabalin versus placebo in targeting pro-nociceptive mechanisms to prevent chronic pain after whiplash injury in at-risk individuals - a feasibility study for a randomised controlled trial. ( 29343280 )
2018
6
Anthropometric characteristics and traffic accident circumstances of patients with isolated whiplash injury in University Clinical Hospital Mostar. ( 29214988 )
2018
7
Neck-specific exercise improves impaired interactions between ventral neck muscles in chronic whiplash: A randomized controlled ultrasound study. ( 29941911 )
2018
8
Excessive Daytime Sleepiness and Injury of the Ascending Reticular Activating System Following Whiplash Injury. ( 29896079 )
2018
9
Investigation of the Effect of Neck Muscle Active Force on Whiplash Injury of the Cervical Spine. ( 29849760 )
2018
10
Evidence for Increased MRI Signal Intensity and Morphological Changes in the Brachial Plexus and Median Nerves of Patients With Chronic Arm and Neck Pain Following Whiplash Injury. ( 29690828 )
2018
11
More whiplash weather in store for California. ( 29717236 )
2018
12
Reciprocal associations of pain and post-traumatic stress symptoms after whiplash injury: A longitudinal, cross-lagged study. ( 29377453 )
2018
13
Validity and test-retest reliability of the Dutch modified Perceived Deficits Questionnaire to examine cognitive symptoms in women with chronic whiplash, chronic idiopathic neck pain and fibromyalgia. ( 29383819 )
2018
14
Lateral atlantoaxial joint meniscoid volume in individuals with whiplash associated disorder: A case-control study. ( 29153925 )
2018
15
Pathology and Treatment of Traumatic Cervical Spine Syndrome: Whiplash Injury. ( 29682354 )
2018
16
Information needs of patients with whiplash associated disorders: A Delphi study of patient beliefs. ( 29073494 )
2018
17
Long-term follow-up of whiplash injuries reported to insurance companies: a cohort study on patient-reported outcomes and impact of financial compensation. ( 29429037 )
2018
18
Is Delayed Surgery After Unsuccessful Conservative Treatment Beneficial for Spinal Cord Injury Following Whiplash? A Retrospective Study in Elderly Patients. ( 29729179 )
2018
19
Superior outcomes following cervical fusion vs. multimodal rehabilitation in a subgroup of randomized Whiplash-Associated-Disorders (WAD) patients indicating somatic pain origin-Comparison of outcome assessments made by four examiners from different disciplines. ( 29794310 )
2018
20
The Discrepancy between Subjective and Objective Measures of Convergence Insufficiency in Whiplash-Associated Disorder versus Control Participants. ( 29371010 )
2018
21
A narrative review on cervical interventions in adults with chronic whiplash-associated disorder. ( 29719724 )
2018
22
Can a Chronic BPPV With a History of Trauma be the Trigger of Symptoms in Vestibular Migraine, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and Whiplash Associated Disorders (WAD)? A Retrospective Cohort Study. ( 30303941 )
2018
23
Swallow Syncope After Whiplash Neck Injury. ( 29658863 )
2018
24
Alterations in the Mechanical Response of Deep Dorsal Neck Muscles in Individuals Experiencing Whiplash-Associated Disorders Compared to Healthy Controls: An Ultrasound Study. ( 29016400 )
2018
25
Regarding Modulation of Central Sensitization Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. ( 29092067 )
2018
26
Psychological Factors and the Development of Chronic Whiplash-associated Disorder(s): A Systematic Review. ( 29470185 )
2018
27
A Review of Traumatic Axonal Injury following Whiplash Injury As Demonstrated by Diffusion Tensor Tractography. ( 29472891 )
2018
28
Cervical extension traction as part of a multimodal rehabilitation program relieves whiplash-associated disorders in a patient having failed previous chiropractic treatment: a CBP® case report. ( 29545691 )
2018
29
Assessing the existence of dissociative PTSD in sub-acute patients of whiplash. ( 29547063 )
2018
30
Thoracic dysfunction in whiplash associated disorders: A systematic review. ( 29570722 )
2018
31
Characteristics and status of Korean medicine use in whiplash-associated disorder patients. ( 29625626 )
2018
32
Exploring patients' experiences of the whiplash injury-recovery process - a meta-synthesis. ( 29988716 )
2018
33
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN A CASE OF WHIPLASH MACULOPATHY WITH INCOMPLETE RESOLUTION. ( 30074572 )
2018
34
Adoption and use of guidelines for whiplash: an audit of insurer and health professional practice in New South Wales, Australia. ( 30089495 )
2018
35
Neck-specific exercise may reduce radiating pain and signs of neurological deficits in chronic whiplash - Analyses of a randomized clinical trial. ( 30120313 )
2018
36
Validation of an index of Sensitivity to Movement-Evoked Pain in patients with whiplash injuries. ( 30123856 )
2018
37
Factors associated with work ability following exercise interventions for people with chronic whiplash-associated disorders: Secondary analysis of a randomized controlled trial. ( 30132011 )
2018
38
Correction: A narrative review on cervical interventions in adults with chronic whiplash-associated disorder. ( 30167322 )
2018
39
Relationship between neck motion and self-reported pain in patients with whiplash associated disorders during the acute phase. ( 30218881 )
2018
40
Physiotherapist-delivered Stress Inoculation Training for acute whiplash-associated disorders: A qualitative study of perceptions and experiences. ( 30218882 )
2018
41
The effect of three exercise approaches on health-related quality of life, and factors associated with its improvement in chronic whiplash-associated disorders: analysis of a randomized controlled trial. ( 30225786 )
2018
42
Acupuncture for treating whiplash-associated disorder: A systematic review and meta-analysis protocol. ( 30313054 )
2018
43
Can cortisol levels predict the severity of acute whiplash-associated disorders? ( 30315329 )
2018
44
Use of and attitudes to the role of medication for acute whiplash injury: A preliminary survey of emergency department doctors. ( 30317691 )
2018
45
Trajectories of posttraumatic stress symptoms after whiplash: A prospective cohort study. ( 30318773 )
2018
46
Whiplash Patients' Responses on the Impact of Events Scale-R - Congruent With Pain or PTSD Symptoms? ( 30371516 )
2018
47
Relationship Between Psychosocial Factors and Pain in the Jaw and Neck Regions Shortly After Whiplash Trauma. ( 30371684 )
2018
48
A core outcome set for clinical trials in whiplash-associated disorders (WAD): a study protocol. ( 30454057 )
2018
49
Has the quality of physiotherapy care in patients with Whiplash-associated disorders (WAD) improved over time? A retrospective study using routinely collected data and quality indicators. ( 30519001 )
2018
50
Agreement is very low between a clinical prediction rule and physiotherapist assessment for classifying the risk of poor recovery of individuals with acute whiplash injury. ( 30522090 )
2018

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.29 CCL3 CCL4 CCL5 CCR5 IL16
2
Show member pathways
13.07 CCL3 CCL4 CCL5 CCR5 IL16
3
Show member pathways
13 CCL3 CCL4 CCL5 CCR5 IL16
4
Show member pathways
12.9 CCL3 CCL4 CCL5 CCR5 IL16
5
Show member pathways
12.72 CCL3 CCL4 CCL5 CCR5
6
Show member pathways
12.57 CCL3 CCL4 CCL5 CCR5
7
Show member pathways
11.88 CCL3 CCL4 CCL5 CCR5
8
Show member pathways
11.68 CCL3 CCL4 CCL5 IL16
9
Show member pathways
11.63 CCL3 CCL4 CCR5
10 11.35 CCL3 CCL4 CCL5
11
Show member pathways
11.32 CCL3 CCL4 CCL5 CCR5
12 11.23 CCL3 CCL4 CCL5
13 10.69 CCL3 CCL4 CCL5 IL16
14 10.66 CCL3 CCL4 CCL5 IL16
15 10.61 CCL3 CCL4 CCL5 CCR5

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CCL3 CCL4 CCL5 IL16 KNG1
2 extracellular space GO:0005615 9.02 CCL3 CCL4 CCL5 IL16 KNG1

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.91 CCL3 CCL4 CCL5 IL16
2 immune response GO:0006955 9.88 CCL3 CCL4 CCL5 CCR5 IL16
3 positive regulation of GTPase activity GO:0043547 9.84 CCL3 CCL4 CCL5
4 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.83 CCL3 CCL4 CCL5
5 MAPK cascade GO:0000165 9.82 CCL3 CCL5 CCR5
6 cell-cell signaling GO:0007267 9.81 CCL3 CCL4 CCL5 CCR5
7 calcium ion transport GO:0006816 9.8 CCL3 CCL5 CCR5
8 inflammatory response GO:0006954 9.8 CCL3 CCL4 CCL5 CCR5 KNG1
9 cellular response to tumor necrosis factor GO:0071356 9.79 CCL3 CCL4 CCL5
10 cellular response to interferon-gamma GO:0071346 9.76 CCL3 CCL4 CCL5
11 response to toxic substance GO:0009636 9.75 CCL3 CCL4 CCL5
12 cell chemotaxis GO:0060326 9.74 CCL3 CCL5 CCR5
13 neutrophil chemotaxis GO:0030593 9.72 CCL3 CCL4 CCL5
14 cytokine-mediated signaling pathway GO:0019221 9.72 CCL3 CCL4 CCL5 CCR5 IL16
15 cellular response to interleukin-1 GO:0071347 9.71 CCL3 CCL4 CCL5
16 cellular response to organic cyclic compound GO:0071407 9.67 CCL3 CCL5
17 monocyte chemotaxis GO:0002548 9.67 CCL3 CCL4 CCL5
18 positive chemotaxis GO:0050918 9.66 CCL3 CCL5
19 protein kinase B signaling GO:0043491 9.66 CCL3 CCL5
20 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 CCL3 CCL5
21 regulation of sensory perception of pain GO:0051930 9.65 CCL3 COMT
22 dendritic cell chemotaxis GO:0002407 9.64 CCL5 CCR5
23 positive regulation of calcium-mediated signaling GO:0050850 9.63 CCL3 CCL4
24 lymphocyte chemotaxis GO:0048247 9.63 CCL3 CCL4 CCL5
25 macrophage chemotaxis GO:0048246 9.61 CCL3 CCL5
26 positive regulation of calcium ion transport GO:0051928 9.61 CCL3 CCL4 CCL5
27 response to cholesterol GO:0070723 9.6 CCL3 CCR5
28 signaling GO:0023052 9.59 CCL3 CCR5
29 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.56 CCL3 CCR5
30 eosinophil chemotaxis GO:0048245 9.54 CCL3 CCL4 CCL5
31 negative regulation of macrophage apoptotic process GO:2000110 9.52 CCL5 CCR5
32 chemokine-mediated signaling pathway GO:0070098 9.46 CCL3 CCL4 CCL5 CCR5
33 negative regulation by host of viral transcription GO:0043922 9.43 CCL3 CCL4 CCL5
34 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL3 CCL4 CCL5
35 chemotaxis GO:0006935 9.02 CCL3 CCL4 CCL5 CCR5 IL16
36 G protein-coupled receptor signaling pathway GO:0007186 10.02 CCL3 CCL4 CCL5 CCR5 KNG1

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.56 CCL3 CCL4 CCL5 IL16
2 chemokine activity GO:0008009 9.5 CCL3 CCL4 CCL5
3 chemoattractant activity GO:0042056 9.43 CCL3 CCL5
4 phosphatidylinositol phospholipase C activity GO:0004435 9.4 CCL5 CCR5
5 phospholipase activator activity GO:0016004 9.37 CCL3 CCL5
6 CCR chemokine receptor binding GO:0048020 9.33 CCL3 CCL4 CCL5
7 CCR5 chemokine receptor binding GO:0031730 9.13 CCL3 CCL4 CCL5
8 CCR1 chemokine receptor binding GO:0031726 8.8 CCL3 CCL4 CCL5

Sources for Whiplash

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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