Aliases & Classifications for Whiplash

MalaCards integrated aliases for Whiplash:

Name: Whiplash 54

Summaries for Whiplash

NINDS : 54 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to cervicitis and avoidant personality disorder. An important gene associated with Whiplash is CCL5 (C-C Motif Chemokine Ligand 5), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Central Nervous System Depressants and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and spinal cord.

Wikipedia : 76 Whiplash is a 2014 American drama film written and directed by Damien Chazelle. It depicts the... more...

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 cervicitis 10.7
2 avoidant personality disorder 10.3 CCL5 CCR5
3 omsk hemorrhagic fever 10.3 CCL4 CCL5
4 chronic pain 10.3
5 yellow fever 10.3 CCL5 CCR5
6 acute cervicitis 10.3 CCL4 CCL5
7 headache 10.3
8 oral lichen planus 10.3 CCL5 CCR5
9 pulmonary sarcoidosis 10.2 CCL5 CCR5
10 depression 10.2
11 inclusion conjunctivitis 10.1 CCL5 IL16
12 fibromyalgia 10.1
13 viral meningitis 10.1 CCL5 IL16
14 aging 9.9
15 respiratory syncytial virus infectious disease 9.9 CCL3 CCL5
16 thoracic outlet syndrome 9.9
17 paine syndrome 9.9
18 cerebritis 9.9
19 radiculopathy 9.9
20 anxiety 9.9
21 brain injury 9.9
22 spinal cord injury 9.9
23 traumatic brain injury 9.9
24 back pain 9.9
25 autoinflammation, lipodystrophy, and dermatosis syndrome 9.8 CCL3 CCL5
26 bronchiolitis 9.8 CCL3 CCL5
27 allergic asthma 9.8 CCL5 IL16
28 necatoriasis 9.8 CCL3 CCL4
29 vertigo, benign recurrent 9.7
30 toxic encephalopathy 9.7
31 body mass index quantitative trait locus 1 9.7
32 carotid artery dissection 9.7
33 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
34 cerebrospinal fluid leak 9.7
35 perilymphatic fistula 9.7
36 acoustic neuroma 9.7
37 transient global amnesia 9.7
38 benign paroxysmal positional nystagmus 9.7
39 encephalopathy 9.7
40 neuroma 9.7
41 head injury 9.7
42 post-traumatic stress disorder 9.7
43 occipital neuralgia 9.7
44 dermatitis 9.7
45 neurogenic thoracic outlet syndrome 9.7
46 trypanosomiasis 9.7 CCL3 CCL5
47 night blindness, congenital stationary, type 1a 9.7 CCL3 CCL4
48 acquired immunodeficiency syndrome 9.6 CCL3 CCR5
49 encephalitis 9.6 CCL5 CCR5
50 chagas disease 9.6 CCL3 CCR5

Graphical network of the top 20 diseases related to Whiplash:



Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Central Nervous System Depressants Phase 4,Phase 2,Not Applicable
2 Anesthetics Phase 4,Not Applicable
3 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
4
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
5
Amitriptyline Approved Phase 2 50-48-6 2160
6
Ibuprofen Approved Phase 2 15687-27-1 3672
7
Ethanol Approved Phase 2 64-17-5 702
8
Cyclobenzaprine Approved Phase 2 303-53-7 2895
9
Butyric Acid Experimental, Investigational Phase 2 107-92-6 264
10 Analgesics Phase 2,Not Applicable
11 Cortisol succinate Phase 2
12 Analgesics, Non-Narcotic Phase 2,Not Applicable
13 Hydrocortisone 17-butyrate 21-propionate Phase 2
14 Hydrocortisone acetate Phase 2
15 Hydrocortisone-17-butyrate Phase 2
16 Anti-Inflammatory Agents Phase 2,Not Applicable
17 Anti-Inflammatory Agents, Non-Steroidal Phase 2,Not Applicable
18 Antirheumatic Agents Phase 2,Not Applicable
19 Adrenergic Agents Phase 2
20 Amitriptyline, perphenazine drug combination Phase 2
21 Neuromuscular Agents Phase 2
22 Neurotransmitter Agents Phase 2
23 Cyclooxygenase Inhibitors Phase 2
24 Neurotransmitter Uptake Inhibitors Phase 2
25 Tranquilizing Agents Phase 2
26 Antidepressive Agents Phase 2
27 Antidepressive Agents, Tricyclic Phase 2
28 Psychotropic Drugs Phase 2
29
Mannitol Approved, Investigational Not Applicable 69-65-8 453 6251
30
Triamcinolone Approved, Vet_approved Not Applicable 124-94-7 31307
31
Levobupivacaine Approved, Investigational Not Applicable 27262-47-1 92253
32
Pyrantel Approved, Vet_approved Not Applicable 15686-83-6
33
Norepinephrine Approved 51-41-2 439260
34
Citalopram Approved 59729-33-8 2771
35
Menthol Approved Not Applicable 2216-51-5 16666
36
Imidacloprid Vet_approved Not Applicable 105827-78-9 86418
37 triamcinolone acetonide Not Applicable
38 Triamcinolone diacetate Not Applicable
39 Triamcinolone hexacetonide Not Applicable
40 Vaccines Early Phase 1
41 Pharmaceutical Solutions Not Applicable
42 Pyranoprofen Not Applicable
43 Pyrantel Pamoate Not Applicable
44 Cholinergic Agents
45 Muscarinic Antagonists
46 Cholinergic Antagonists
47 Serotonin Agents
48 Serotonin Uptake Inhibitors
49 Parasympatholytics
50 Antidepressive Agents, Second-Generation

Interventional clinical trials:

(show top 50) (show all 52)
# Name Status NCT ID Phase Drugs
1 Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity Terminated NCT01255631 Phase 4
2 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder Withdrawn NCT02060734 Phase 4
3 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
4 University Health Network Whiplash Intervention Trial Completed NCT00546806 Phase 3
5 Preventing Chronic Whiplash Pain Completed NCT00021476 Phase 3
6 Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury Completed NCT00206271 Phase 3
7 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
8 Association Between Low Cortisol Levels and Whiplash Syndrome Unknown status NCT02090309 Phase 2 Hydrocortisone;normal saline 0.9%
9 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash? Completed NCT01512576 Phase 2
10 Acupuncture for Whiplash Associated Disorder Completed NCT01395511 Phase 2
11 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2 Cyclobenzaprine;Ibuprofen;Ibuprofen plus Cyclobenzaprine
12 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain Completed NCT01518530 Phase 2
13 Whiplash-associated Disorders - Needling Treatments Pilot Study Unknown status NCT01824810 Not Applicable
14 Is Chronic Whiplash-associated Pain of Neurogenic Origin? Unknown status NCT02692937 Not Applicable
15 East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders Unknown status NCT01369238 Not Applicable zaltoprofen
16 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Unknown status NCT01544075 Early Phase 1
17 Treatment of Whiplash Associated Disorders by APOS Kit Unknown status NCT00266981 Not Applicable
18 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
19 A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138 Not Applicable
20 Neuroscience Education on Osteoarthritis Unknown status NCT02246088 Not Applicable
21 RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain Unknown status NCT01743326 Not Applicable
22 Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study Unknown status NCT00510757
23 Measuring the Impact of the French Version of the Whiplash Book Completed NCT03040245
24 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders Completed NCT01601912 Atomoxetine;Citalopram
25 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders Completed NCT01528579 Not Applicable
26 Manual Therapy to Treat Acute Whiplash Injury Completed NCT01825460 Not Applicable
27 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624 Not Applicable
28 Randomized WAD Study Completed NCT01994044 Not Applicable
29 Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain Completed NCT01431261 Not Applicable
30 Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033 Not Applicable
31 Icing Effects on Neck Functions of the Boxers Completed NCT01203280 Not Applicable
32 Explain Pain in Fibromyalgia Patients Completed NCT02474875 Not Applicable
33 Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training Completed NCT02098005 Not Applicable
34 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143 Not Applicable
35 Concussion in Motor Vehicle Accidents: The Concussion Identification Index Completed NCT02858544
36 Why Does Acute Post Whiplash Injury Pain Transform Into Chronic Pain? Recruiting NCT02560675
37 Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders Recruiting NCT02251028 Not Applicable
38 Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting Recruiting NCT02570659 Not Applicable
39 Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders Recruiting NCT03239938 Not Applicable
40 Neck-specific Exercise in Chronic Whiplash Recruiting NCT03022812 Not Applicable
41 Modeling Post-traumatic Pain and Recovery: The SYMBIOME Longitudinal Cohort Study Recruiting NCT02711085
42 Postural Garment Versus Exercises for Women With Cervical Pain Recruiting NCT03560492 Not Applicable
43 Clinical Effect Size of an Educational Intervention in the Home and Compliance on People Who Suffer From Stroke Recruiting NCT01980641 Not Applicable
44 Effectiveness of an Educational Video Following Acute Whiplash Trauma Active, not recruiting NCT01699334 Not Applicable
45 Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries Active, not recruiting NCT02157038 Early Phase 1
46 Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention. Enrolling by invitation NCT02625896 Not Applicable
47 Correlation Between Central Sensitization Inventory and Posturographic Data Enrolling by invitation NCT03058003
48 Central Sensitization in Chronic Whiplash Patients Not yet recruiting NCT03005691
49 Efficacy of the Use of Dry Needling in Conventional Non-invasive Treatment of Acute and Subacute Whiplash Not yet recruiting NCT03502928 Not Applicable
50 Influence of Beliefs on the Prognosis of Chronic Musculoskeletal Pain. Not yet recruiting NCT03036553

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

41
Testes, Eye, Spinal Cord, Brain, Bone, Tongue, Skin

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 664)
# Title Authors Year
1
Intramuscular fat is present in cervical multifidus but not soleus in patients with chronic whiplash associated disorders. ( 29795590 )
2018
2
Biomechanics of coupled motion in the cervical spine during simulated whiplash in patients with pre-existing cervical or lumbar spinal fusion: A Finite Element Study. ( 29330341 )
2018
3
Whiplash injury results in sustained impairments of cervical muscle function: A one-year prospective, controlled study. ( 29767228 )
2018
4
Pregabalin versus placebo in targeting pro-nociceptive mechanisms to prevent chronic pain after whiplash injury in at-risk individuals - a feasibility study for a randomised controlled trial. ( 29343280 )
2018
5
Anthropometric characteristics and traffic accident circumstances of patients with isolated whiplash injury in University Clinical Hospital Mostar. ( 29214988 )
2018
6
Neck-specific exercise improves impaired interactions between ventral neck muscles in chronic whiplash: A randomized controlled ultrasound study. ( 29941911 )
2018
7
Excessive Daytime Sleepiness and Injury of the Ascending Reticular Activating System Following Whiplash Injury. ( 29896079 )
2018
8
Investigation of the Effect of Neck Muscle Active Force on Whiplash Injury of the Cervical Spine. ( 29849760 )
2018
9
Evidence for Increased MRI Signal Intensity and Morphological Changes in the Brachial Plexus and Median Nerves of Patients With Chronic Arm and Neck Pain Following Whiplash Injury. ( 29690828 )
2018
10
More whiplash weather in store for California. ( 29717236 )
2018
11
Reciprocal associations of pain and post-traumatic stress symptoms after whiplash injury: A longitudinal, cross-lagged study. ( 29377453 )
2018
12
Validity and test-retest reliability of the Dutch modified Perceived Deficits Questionnaire to examine cognitive symptoms in women with chronic whiplash, chronic idiopathic neck pain and fibromyalgia. ( 29383819 )
2018
13
Pathology and Treatment of Traumatic Cervical Spine Syndrome: Whiplash Injury. ( 29682354 )
2018
14
Information needs of patients with whiplash associated disorders: A Delphi study of patient beliefs. ( 29073494 )
2018
15
Long-term follow-up of whiplash injuries reported to insurance companies: a cohort study on patient-reported outcomes and impact of financial compensation. ( 29429037 )
2018
16
Is Delayed Surgery After Unsuccessful Conservative Treatment Beneficial for Spinal Cord Injury Following Whiplash? A Retrospective Study in Elderly Patients. ( 29729179 )
2018
17
Superior outcomes following cervical fusion vs. multimodal rehabilitation in a subgroup of randomized Whiplash-Associated-Disorders (WAD) patients indicating somatic pain origin-Comparison of outcome assessments made by four examiners from different disciplines. ( 29794310 )
2018
18
The Discrepancy between Subjective and Objective Measures of Convergence Insufficiency in Whiplash-Associated Disorder versus Control Participants. ( 29371010 )
2018
19
A narrative review on cervical interventions in adults with chronic whiplash-associated disorder. ( 29719724 )
2018
20
Isometric muscle fatigue of the paravertebral and upper extremity muscles after whiplash injury. ( 28761029 )
2017
21
Exercise induced hypoalgesia is elicited by isometric, but not aerobic exercise in individuals with chronic whiplash associated disorders. ( 28850338 )
2017
22
Treatment of chronic canalithiasis can be beneficial for patients with vertigo/dizziness and chronic musculoskeletal pain, including whiplash related pain. ( 29911614 )
2017
23
The whiplash enigma: Still searching for answers. ( 29913716 )
2017
24
Whiplash Syndrome- a disorder of the brain? ( 28697186 )
2017
25
Magnetic Resonance Imaging-Based Prediction of the Relationship between Whiplash Injury and Temporomandibular Disorders. ( 29375466 )
2017
26
Evidence for cervical muscle morphometric changes on magnetic resonance images after whiplash: A systematic review and meta-analysis. ( 29269107 )
2017
27
Cost-effectiveness of neck-specific exercise with or without a behavioral approach versus physical activity prescription in the treatment of chronic whiplash-associated disorders: Analyses of a randomized clinical trial. ( 28640136 )
2017
28
The Whiplash Rash. ( 28761857 )
2017
29
Persistent pseudomyopia following a whiplash injury in a previously emmetropic woman. ( 29260112 )
2017
30
Distribution of concussion related symptoms after whiplash injury in risk strata. ( 29913815 )
2017
31
Post-traumatic stress symptom clusters in acute whiplash associated disorder and their prediction of chronic pain-related disability. ( 29392244 )
2017
32
Symptoms, disabilities, and life satisfaction five years after whiplash injuries. ( 29911576 )
2017
33
Epidemiology and psychological factors of whiplash associated disorders in Japanese population. ( 28931977 )
2017
34
Motor evoked potentials in patients with chronic whiplash-associated disorder grade II. ( 28711376 )
2017
35
Living with ongoing whiplash associated disorders: a qualitative study of individual perceptions and experiences. ( 29246144 )
2017
36
Association between Clinical and Neurophysiological Outcomes in Patients with Mechanical Neck Pain and Whiplash-associated Disorders. ( 28678060 )
2017
37
Chronic whiplash, pain and pain tolerance. ( 29913692 )
2017
38
Decreased Regional Grey Matter Volume in Women with Chronic Whiplash-Associated Disorders: Relationships with Cognitive Deficits and Disturbed Pain Processing. ( 29149149 )
2017
39
Pharmacological modulation of chronic pain after whiplash injury. ( 29913794 )
2017
40
Advancing imaging technologies for patients with spinal pain: with a focus on whiplash injury. ( 28774580 )
2017
41
Whiplash Associated Disorders (WAD): Responses to pharmacological challenges and psychometric tests. ( 29913863 )
2017
42
New objective findings after whiplash injuries: High blood flow in painful cervical soft tissue: An ultrasound pilot study. ( 29913629 )
2017
43
Neck-specific exercises with internet-based support compared to neck-specific exercises at a physiotherapy clinic for chronic whiplash-associated disorders: study protocol of a randomized controlled multicentre trial. ( 29233141 )
2017
44
Cross-sectional and Prospective Correlates of Recovery Expectancies in the Rehabilitation of Whiplash Injury. ( 28799973 )
2017
45
Predictors before and after multimodal rehabilitation for pain acceptance and engagement in activities at a 1-year follow-up for patients with whiplash-associated disorders (WAD)-a study based on the Swedish Quality Registry for Pain Rehabilitation (SQRP). ( 29155342 )
2017
46
Appropriate interventional management of whiplash-associated pain disorders is effective. ( 29913868 )
2017
47
Effects on jaw function shortly after whiplash trauma. ( 28891205 )
2017
48
Whiplash Injury: Perspectives on the Development of Chronic Pain. ( 28759489 )
2017
49
Women with late whiplash syndrome have greatly reduced load-bearing of the cervical spine. In vivo biomechanical, cross-sectional, lateral radiographic study. ( 28714657 )
2017
50
Assessment of Range of Movement, Pain and Disability Following a Whiplash Injury. ( 28839498 )
2017

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.22 CCL3 CCL4 CCL5 CCR5 IL16
2
Show member pathways
13.07 CCL3 CCL4 CCL5 IL16
3
Show member pathways
13 CCL3 CCL4 CCL5 CCR5 IL16
4
Show member pathways
12.96 CCL3 CCL4 CCL5 CCR5
5
Show member pathways
12.91 CCL3 CCL4 CCL5 CCR5 IL16
6
Show member pathways
12.83 CCL3 CCL4 CCL5 CCR5 IL16
7
Show member pathways
12.49 CCL3 CCL4 CCL5 CCR5
8
Show member pathways
11.57 CCL3 CCL4 CCL5 IL16
9
Show member pathways
11.55 CCL3 CCL4 CCR5
10 11.46 CCL3 CCL5
11 11.43 CCL3 CCL4
12
Show member pathways
11.32 CCL3 CCL4 CCL5 CCR5
13 11.13 CCL3 CCL4 CCL5
14 10.61 CCL3 CCL4 CCL5 CCR5

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CCL3 CCL4 CCL5 IL16 KNG1
2 extracellular space GO:0005615 9.02 CCL3 CCL4 CCL5 IL16 KNG1

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 37)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.89 CCL3 CCL4 CCL5 IL16
2 immune response GO:0006955 9.85 CCL3 CCL4 CCL5 CCR5 IL16
3 positive regulation of GTPase activity GO:0043547 9.83 CCL3 CCL4 CCL5
4 cell-cell signaling GO:0007267 9.83 CCL3 CCL4 CCL5 CCR5
5 MAPK cascade GO:0000165 9.82 CCL3 CCL5 CCR5
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.81 CCL3 CCL4 CCL5
7 calcium ion transport GO:0006816 9.79 CCL3 CCL5 CCR5
8 cellular response to tumor necrosis factor GO:0071356 9.78 CCL3 CCL4 CCL5
9 inflammatory response GO:0006954 9.77 CCL3 CCL4 CCL5 CCR5 KNG1
10 response to toxic substance GO:0009636 9.75 CCL3 CCL4 CCL5
11 cellular response to interferon-gamma GO:0071346 9.74 CCL3 CCL4 CCL5
12 cytokine-mediated signaling pathway GO:0019221 9.72 CCL3 CCL4 CCL5 CCR5 IL16
13 cellular response to interleukin-1 GO:0071347 9.71 CCL3 CCL4 CCL5
14 neutrophil chemotaxis GO:0030593 9.69 CCL3 CCL4 CCL5
15 positive regulation of inflammatory response GO:0050729 9.67 CCL3 CCL4
16 cell chemotaxis GO:0060326 9.67 CCL3 CCL5
17 cellular response to organic cyclic compound GO:0071407 9.67 CCL3 CCL5
18 monocyte chemotaxis GO:0002548 9.67 CCL3 CCL4 CCL5
19 calcium-mediated signaling GO:0019722 9.66 CCL3 CCR5
20 protein kinase B signaling GO:0043491 9.65 CCL3 CCL5
21 positive chemotaxis GO:0050918 9.65 CCL3 CCL5
22 lymphocyte chemotaxis GO:0048247 9.65 CCL3 CCL4 CCL5
23 signaling GO:0023052 9.64 CCL3 CCR5
24 lipopolysaccharide-mediated signaling pathway GO:0031663 9.64 CCL3 CCL5
25 positive regulation of calcium-mediated signaling GO:0050850 9.63 CCL3 CCL4
26 dendritic cell chemotaxis GO:0002407 9.62 CCL5 CCR5
27 macrophage chemotaxis GO:0048246 9.61 CCL3 CCL5
28 eosinophil chemotaxis GO:0048245 9.61 CCL3 CCL4 CCL5
29 response to cholesterol GO:0070723 9.58 CCL3 CCR5
30 positive regulation of calcium ion transport GO:0051928 9.58 CCL3 CCL4 CCL5
31 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.56 CCL3 CCR5
32 negative regulation of macrophage apoptotic process GO:2000110 9.55 CCL5 CCR5
33 chemokine-mediated signaling pathway GO:0070098 9.46 CCL3 CCL4 CCL5 CCR5
34 negative regulation by host of viral transcription GO:0043922 9.43 CCL3 CCL4 CCL5
35 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL3 CCL4 CCL5
36 chemotaxis GO:0006935 9.02 CCL3 CCL4 CCL5 CCR5 IL16
37 G-protein coupled receptor signaling pathway GO:0007186 10 CCL3 CCL4 CCL5 CCR5 KNG1

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.56 CCL3 CCL4 CCL5 IL16
2 chemokine activity GO:0008009 9.5 CCL3 CCL4 CCL5
3 chemoattractant activity GO:0042056 9.43 CCL3 CCL5
4 phosphatidylinositol phospholipase C activity GO:0004435 9.4 CCL5 CCR5
5 phospholipase activator activity GO:0016004 9.37 CCL3 CCL5
6 CCR chemokine receptor binding GO:0048020 9.33 CCL3 CCL4 CCL5
7 CCR5 chemokine receptor binding GO:0031730 9.13 CCL3 CCL4 CCL5
8 CCR1 chemokine receptor binding GO:0031726 8.8 CCL3 CCL4 CCL5

Sources for Whiplash

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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