WT4
MCID: WLM017
MIFTS: 18

Wilms Tumor 4 (WT4)

Categories: Blood diseases, Cancer diseases, Fetal diseases, Genetic diseases, Nephrological diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Wilms Tumor 4

MalaCards integrated aliases for Wilms Tumor 4:

Name: Wilms Tumor 4 57 29 70
Familial Wilms Tumor 1; Fwt1 57
Familial Wilms Tumor 1 57
Wilms Tumor, Type 4 57
Wilms Tumor-4 13
Fwt1 57
Wt4 57

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal dominant

Miscellaneous:
familial form
presents at a later age than sporadic wilms tumor
presents at a later stage than sporadic wilms tumor


HPO:

31
wilms tumor 4:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM® 57 601363
OMIM Phenotypic Series 57 PS194070
MedGen 41 C1832426
SNOMED-CT via HPO 68 25081006 263681008 302849000
UMLS 70 C1832426

Summaries for Wilms Tumor 4

MalaCards based summary : Wilms Tumor 4, also known as familial wilms tumor 1; fwt1, is related to wilms tumor 1 and familial wilms tumor 2. An important gene associated with Wilms Tumor 4 is WT4 (Wilms Tumor-4). Related phenotype is nephroblastoma.

More information from OMIM: 601363 PS194070

Related Diseases for Wilms Tumor 4

Diseases in the Hereditary Wilms' Tumor family:

Wilms Tumor 1 Wilms Tumor 2
Wilms Tumor 3 Wilms Tumor 4
Wilms Tumor 5 Wilms Tumor 6
Familial Wilms Tumor 2

Diseases related to Wilms Tumor 4 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wilms tumor 1 9.9
2 familial wilms tumor 2 9.9

Symptoms & Phenotypes for Wilms Tumor 4

Human phenotypes related to Wilms Tumor 4:

31
# Description HPO Frequency HPO Source Accession
1 nephroblastoma 31 HP:0002667

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
Genitourinary Kidneys:
nephroblastoma (wilms tumor)

Neoplasia:
nephroblastoma (wilms tumor)

Clinical features from OMIM®:

601363 (Updated 20-May-2021)

Drugs & Therapeutics for Wilms Tumor 4

Search Clinical Trials , NIH Clinical Center for Wilms Tumor 4

Genetic Tests for Wilms Tumor 4

Genetic tests related to Wilms Tumor 4:

# Genetic test Affiliating Genes
1 Wilms Tumor 4 29

Anatomical Context for Wilms Tumor 4

Publications for Wilms Tumor 4

Articles related to Wilms Tumor 4:

# Title Authors PMID Year
1
Confirmation of FWT1 as a Wilms' tumour susceptibility gene and phenotypic characteristics of Wilms' tumour attributable to FWT1. 57
9860296 1998
2
Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12-q21. 57
8696342 1996
3
Secondary renal neoplasia following chemotherapy or radiation in pediatric patients. 61
32681944 2020
4
Prospective use of the single-mouse experimental design for the evaluation of PLX038A. 61
31927611 2020
5
Anesthesia for pediatric external beam radiation therapy. 61
10348288 1999
6
Hepatic resection for secondary neoplasms. 61
6289486 1982
7
Diagnostic value of cytologic specimens obtained from children with cancer. 61
169727 1975
8
Bilateral Wilms tumor: 4-year survival. 61
4330020 1971

Variations for Wilms Tumor 4

Expression for Wilms Tumor 4

Search GEO for disease gene expression data for Wilms Tumor 4.

Pathways for Wilms Tumor 4

GO Terms for Wilms Tumor 4

Sources for Wilms Tumor 4

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....