WT4
MCID: WLM017
MIFTS: 19

Wilms Tumor 4 (WT4)

Categories: Cancer diseases, Fetal diseases, Genetic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Wilms Tumor 4

MalaCards integrated aliases for Wilms Tumor 4:

Name: Wilms Tumor 4 58 74
Familial Wilms Tumor 1; Fwt1 58
Familial Wilms Tumor 1 58
Wilms Tumor, Type 4 58
Wilms Tumor-4 13
Fwt1 58
Wt4 58

Characteristics:

OMIM:

58
Inheritance:
autosomal dominant

Miscellaneous:
familial form
presents at a later age than sporadic wilms tumor
presents at a later stage than sporadic wilms tumor


HPO:

33
wilms tumor 4:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 58 601363
MedGen 43 C1832426
SNOMED-CT via HPO 70 25081006 263681008 302849000
UMLS 74 C1832426

Summaries for Wilms Tumor 4

MalaCards based summary : Wilms Tumor 4, also known as familial wilms tumor 1; fwt1, is related to wilms tumor 5 and wilms tumor 6. An important gene associated with Wilms Tumor 4 is WT4 (Wilms Tumor-4). Related phenotype is nephroblastoma.

Description from OMIM: 601363

Related Diseases for Wilms Tumor 4

Diseases in the Hereditary Wilms' Tumor family:

Wilms Tumor 1 Wilms Tumor 2
Wilms Tumor 3 Wilms Tumor 4
Wilms Tumor 5 Wilms Tumor 6
Familial Wilms Tumor 2

Diseases related to Wilms Tumor 4 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wilms tumor 5 11.1
2 wilms tumor 6 10.1
3 familial wilms tumor 2 10.1

Symptoms & Phenotypes for Wilms Tumor 4

Human phenotypes related to Wilms Tumor 4:

33
# Description HPO Frequency HPO Source Accession
1 nephroblastoma 33 HP:0002667

Symptoms via clinical synopsis from OMIM:

58
Genitourinary Kidneys:
nephroblastoma (wilms tumor)

Neoplasia:
nephroblastoma (wilms tumor)

Clinical features from OMIM:

601363

Drugs & Therapeutics for Wilms Tumor 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CT Indexes of Emphysema and Airways in Healthy Volunteers: Normal Values; Relations With Gender, Height and Weight Completed NCT02611947

Search NIH Clinical Center for Wilms Tumor 4

Genetic Tests for Wilms Tumor 4

Anatomical Context for Wilms Tumor 4

Publications for Wilms Tumor 4

Articles related to Wilms Tumor 4:

# Title Authors Year
1
Mixing Atomistic and Coarse Grain Solvation Models for MD Simulations: Let WT4 Handle the Bulk. ( 26593029 )
2012
2
Bilateral Wilms tumor: 4-year survival. ( 4330020 )
1971

Variations for Wilms Tumor 4

Expression for Wilms Tumor 4

Search GEO for disease gene expression data for Wilms Tumor 4.

Pathways for Wilms Tumor 4

GO Terms for Wilms Tumor 4

Sources for Wilms Tumor 4

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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