MCID: WLM019
MIFTS: 14

Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome

Categories: Neuronal diseases, Metabolic diseases, Mental diseases

Aliases & Classifications for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

MalaCards integrated aliases for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

Name: Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 57 29 6 40 73
Wagro Syndrome 57 13
Chromosome 11p13-P12 Deletion Syndrome 57
Wagr Syndrome with Obesity 57
Wagro 57

Classifications:



External Ids:

OMIM 57 612469
MedGen 42 C2675904
UMLS 73 C2675904

Summaries for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

OMIM : 57 For a detailed discussion of the WAGR syndrome, see 194072. In a subgroup of individuals with the WAGR syndrome, obesity develops. The phenotype in this subset is associated with haploinsufficiency for the BDNF gene. (612469)

MalaCards based summary : Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome, also known as wagro syndrome, is related to wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome and succinic semialdehyde dehydrogenase deficiency. An important gene associated with Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome is WAGRO (WAGRO Syndrome).

Related Diseases for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Diseases related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome 9.9
2 succinic semialdehyde dehydrogenase deficiency 9.9

Symptoms & Phenotypes for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Clinical features from OMIM:

612469

Drugs & Therapeutics for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Search Clinical Trials , NIH Clinical Center for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome

Genetic Tests for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Genetic tests related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

# Genetic test Affiliating Genes
1 Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 29

Anatomical Context for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Publications for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Articles related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

# Title Authors Year
1
The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome. ( 23266638 )
2013

Variations for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

ClinVar genetic disease variations for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 subset of 41 genes:PAX6; WT1 GRCh37/hg19 11p15.1-13(chr11: 21586131-33168232)x1 copy number loss Pathogenic GRCh37 Chromosome 11, 21586131: 33168232

Expression for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Search GEO for disease gene expression data for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome.

Pathways for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

GO Terms for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Sources for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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