WAGRO
MCID: WLM019
MIFTS: 14

Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome (WAGRO)

Categories: Mental diseases, Metabolic diseases, Neuronal diseases

Aliases & Classifications for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

MalaCards integrated aliases for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

Name: Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 58 30 6 41 74
Wagro Syndrome 58 13
Chromosome 11p13-P12 Deletion Syndrome 58
Wagr Syndrome with Obesity 58
Wagro 58

Classifications:



External Ids:

OMIM 58 612469
MedGen 43 C2675904
UMLS 74 C2675904

Summaries for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

OMIM : 58 For a detailed discussion of the WAGR syndrome, see 194072. In a subgroup of individuals with the WAGR syndrome, obesity develops. The phenotype in this subset is associated with haploinsufficiency for the BDNF gene. (612469)

MalaCards based summary : Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome, also known as wagro syndrome, is related to wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome and succinic semialdehyde dehydrogenase deficiency. An important gene associated with Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome is WAGRO (WAGRO Syndrome).

Related Diseases for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Diseases related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome 10.0
2 succinic semialdehyde dehydrogenase deficiency 10.0

Symptoms & Phenotypes for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Clinical features from OMIM:

612469

Drugs & Therapeutics for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Search Clinical Trials , NIH Clinical Center for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome

Genetic Tests for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Genetic tests related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

# Genetic test Affiliating Genes
1 Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 30

Anatomical Context for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Publications for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Articles related to Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

# Title Authors Year
1
The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome. ( 23266638 )
2013

Variations for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

ClinVar genetic disease variations for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 subset of 41 genes:PAX6; WT1 GRCh37/hg19 11p15.1-13(chr11: 21586131-33168232)x1 copy number loss Pathogenic GRCh37 Chromosome 11, 21586131: 33168232

Expression for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Search GEO for disease gene expression data for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome.

Pathways for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

GO Terms for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

Sources for Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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