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MCID: WSS007
MIFTS: 24

Wissler-Fanconi Syndrome

Categories: Immune diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Wissler-Fanconi Syndrome

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MalaCards integrated aliases for Wissler-Fanconi Syndrome:

Name: Wissler-Fanconi Syndrome 12 15
Wissler's Syndrome 12 43 17
Wissler's Subsepsis Allergica 12

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3047
MeSH 43 D014924
SNOMED-CT 67 68190001
UMLS 71 C0043195
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Summaries for Wissler-Fanconi Syndrome

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Disease Ontology : 12 A syndrome that is characterized by true sepsis, acute rheumatic fever, rheumatoid arthritis, and adult onset Still’s disease.

MalaCards based summary : Wissler-Fanconi Syndrome, also known as wissler's syndrome, is related to exanthem and adult-onset still's disease. An important gene associated with Wissler-Fanconi Syndrome is AIRE (Autoimmune Regulator), and among its related pathways/superpathways is Primary immunodeficiency. Affiliated tissues include kidney and testes.

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Related Diseases for Wissler-Fanconi Syndrome

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Diseases related to Wissler-Fanconi Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
# Related Disease Score Top Affiliating Genes
1 exanthem 29.5 PRTN3 IFNA1 CD4
2 adult-onset still's disease 11.9
3 fanconi renotubular syndrome 2 11.2
4 fanconi syndrome 11.2
5 drug allergy 10.6
6 allergic hypersensitivity disease 10.5
7 pericarditis 10.5
8 rheumatic fever-related antigen 10.3
9 juvenile arthritis 10.3
10 osteonecrosis 10.3
11 urticaria 10.3
12 rheumatic fever 10.3
13 enthesopathy 10.3
14 myocarditis 10.3
15 autoimmune polyendocrine syndrome 10.3 TPH1 AIRE
16 autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia 10.2 TPH1 AIRE
17 adrenal cortex disease 10.2 POMC AIRE
18 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2 PTPRN AIRE
19 pernicious anemia 10.2 PTPRN AIRE
20 opiate dependence 10.1 TPH1 POMC
21 rheumatoid arthritis 10.1
22 ornithosis 10.1
23 arthritis 10.1
24 hypereosinophilic syndrome 10.1
25 pancreatic cystadenoma 10.1 PTPRN POMC
26 rapidly progressive glomerulonephritis 10.1 PRTN3 CNOT11
27 adrenal gland disease 10.1 POMC AIRE
28 dendritic cell thymoma 10.0 CD4 AIRE
29 angular cheilitis 10.0 CD4 AIRE
30 autoimmune peripheral neuropathy 10.0 CD4 AIRE
31 esophageal candidiasis 10.0 CD4 AIRE
32 good syndrome 10.0 CD4 AIRE
33 hypoadrenocorticism, familial 10.0 TPH1 POMC AIRE
34 alopecia universalis congenita 10.0 CD4 AIRE
35 adenohypophysitis 9.9 POMC CD4
36 acute orbital inflammation 9.9 POMC CD4
37 arachnoiditis 9.9 POMC CD4
38 trichinosis 9.9 POMC CD4
39 autoimmune gastritis 9.9 CD4 AIRE
40 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 9.9 CD4 AIRE
41 adrenal cortical hypofunction 9.9 PTPRN POMC AIRE
42 autoimmune disease of skin and connective tissue 9.9 CD4 AIRE
43 endogenous depression 9.9 TPH1 POMC
44 oral candidiasis 9.9 CD4 AIRE
45 thymus gland disease 9.9 CD4 AIRE
46 skin sarcoidosis 9.8 IFNA1 CD4
47 superficial basal cell carcinoma 9.8 IFNA1 CD4
48 common wart 9.8 IFNA1 CD4
49 monkeypox 9.8 IFNA1 CD4
50 thymus cancer 9.8 CD4 AIRE

Graphical network of the top 20 diseases related to Wissler-Fanconi Syndrome:



Diseases related to Wissler-Fanconi Syndrome
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Symptoms & Phenotypes for Wissler-Fanconi Syndrome

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Drugs & Therapeutics for Wissler-Fanconi Syndrome

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Search Clinical Trials , NIH Clinical Center for Wissler-Fanconi Syndrome

Cochrane evidence based reviews: wissler's syndrome

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Genetic Tests for Wissler-Fanconi Syndrome

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Anatomical Context for Wissler-Fanconi Syndrome

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MalaCards organs/tissues related to Wissler-Fanconi Syndrome:

40
Kidney, Testes
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Publications for Wissler-Fanconi Syndrome

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Articles related to Wissler-Fanconi Syndrome:

(show top 50) (show all 90)
# Title Authors PMID Year
1
Wissler-Fanconi syndrome and related diagnoses: a case report. 61
27843372 2016
2
[Subsepsis hyperergica: another way of discussing Wissler-Fanconi syndrome?]. 61
12378838 2002
3
[Can we still speak of Wissler-Fanconi syndrome?]. 61
11928372 2002
4
[Wissler's allergic subsepsis]. 61
8150635 1994
5
[Subsepsis allergica in a patient with type I polyglandular autoimmune syndrome]. 61
2233764 1990
6
[The Wissler-Fanconi syndrome after hysterectomy]. 61
2225106 1990
7
[Acute recurrent urticaria in Wissler-Fanconi syndrome in adult. Apropos of a case]. 61
3187369 1988
8
Hematuria as presenting sign in Wissler-Fanconi syndrome. 61
3572917 1987
9
[Fatal form of pericardo-myocarditis in Wissler-Fanconi syndrome]. 61
3092775 1986
10
[Early diagnosis in Wissler-Fanconi syndrome as an exclusion diagnosis]. 61
3723935 1986
11
[Early indirect diagnosis of Wissler-Fanconi syndrome]. 61
4001021 1985
12
[Wissler-Fanconi syndrome and Still's disease in adults. Nosological and etiological problems and borderline forms. Apropos of 7 cases]. 61
6301051 1983
13
[Wissler-Fanconi syndrome or polyarthritis caused by Yersinia pseudotuberculosis?]. 61
7208327 1981
14
[NBT test in Wissler-Fanconi syndrome]. 61
7413481 1980
15
[Case of Wissler-Fanconi syndrome]. 61
7385881 1980
16
[Wissler-Fanconi syndrome in the light of our observations]. 61
523221 1979
17
[Clinical and nosographic considerations on the Wissler-Fanconi syndrome in childhood]. 61
723824 1978
18
[The Wissler-Fanconi syndrome (allergic subsepsis) in adults]. 61
904713 1977
19
[Differential diagnosis between Wissler-Fanconi syndrome and other clinical syndromes]. 61
834497 1977
20
[The Wissler-Fanconi syndrome. Nogographical classification and case contribution]. 61
1032566 1976
21
[Wissler-Fanconi syndrome or subsepsis hyperergica (1 case)]. 61
1013555 1976
22
[A case of Wissler-Fanconi syndrome in an adult]. 61
1251655 1976
23
[Wissler-Fanconi syndrome in adults]. 61
1251643 1976
24
[Wissler - Fanconi syndrome or Still's disease?]. 61
1251614 1976
25
[Acute abdomen in the Wissler-Fanconi syndrome]. 61
1206854 1975
26
[Immunological aspects of the Wissler-Fanconi syndrome]. 61
1118157 1975
27
[Characteristics of Wissler-Fanconi syndrome in adults]. 61
4466904 1974
28
[Wissler's syndrome--rheumatoid arthritis]. 61
4773979 1973
29
[Still's disease in adults and Wissler-Fanconi syndrome]. 61
4694304 1973
30
[Subsepsis allergica (Wissler's syndrome) in adults: a clinical and morbid-anatomical report]. 61
5075797 1972
31
[Wissler-Fanconi syndrome in adult patients]. 61
5142779 1971
32
[Wissler-Fanconi syndrome in adults in the light of literature data and personal clinical observations]. 61
5138139 1971
33
Wissler's Syndrome Associated with Parainfluenza 2 Infection. 61
25607584 1970
34
[Wissler-Fanconi syndrome in adults]. 61
5505110 1970
35
[Wissler-Fanconi syndrome]. 61
5481804 1970
36
[Wissler-Fanconi syndrome in a man]. 61
5415366 1970
37
[Hypersensitivity against tetracycline as caused for Wissler-Fanconi syndrome]. 61
5504212 1970
38
[Hypersensitivity to tetracycline as a cause of Wissler-Fanconi-syndrome]. 61
5524333 1970
39
[Wissler's syndrome]. 61
5450480 1970
40
[A rare case of Wissler-Fanconi syndrome in an adult]. 61
5212523 1969
41
[Study and definition of acute infantile form of rhumatoid disease (Wissler-Fanconi syndrome)]. 61
5366612 1969
42
[Renal manifestations in Wissler-Fanconi syndrome (clinical contribution)]. 61
5399496 1969
43
[Allergic subsepsis, Wissler's syndrome]. 61
5793627 1969
44
[Wissler's syndrome]. 61
5398336 1969
45
[Generalized arteriitis in infants (Wissler's syndrome)]. 61
4190768 1969
46
[A case of Wissler-Fanconi syndrome]. 61
5792084 1969
47
[A case of Wissler-Fanconi syndrome associated with renal manifestations]. 61
5745335 1968
48
[Pericarditis sicca in a stormy course of Wissler-Fanconi syndrome in a 4-year-old boy]. 61
5701470 1968
49
[An unusual case of Wissler-Fanconi syndrome in an adult woman]. 61
5699254 1968
50
[Dry pericarditis and late-stage nephrosis, spastic crisis of forearm, hand and finger flexors; and, finally, Stilling-Türk-Duane pseudosyndrome complicated by Wissler-Fanconi syndrome in a 6-year-old boy]. 61
5746227 1968
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Variations for Wissler-Fanconi Syndrome

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Expression for Wissler-Fanconi Syndrome

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Search GEO for disease gene expression data for Wissler-Fanconi Syndrome.
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Pathways for Wissler-Fanconi Syndrome

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Pathways related to Wissler-Fanconi Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Primary immunodeficiency 36
10.2 CD4 AIRE
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GO Terms for Wissler-Fanconi Syndrome

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Biological processes related to Wissler-Fanconi Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.02 PTPRN PRTN3 POMC IFNA1 CD4
2 humoral immune response GO:0006959 8.96 IFNA1 AIRE

Molecular functions related to Wissler-Fanconi Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.8 PRTN3 POMC CD4
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Sources for Wissler-Fanconi Syndrome

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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