MCID: WLF003
MIFTS: 22

Wolffian Duct Adenoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Wolffian Duct Adenoma

MalaCards integrated aliases for Wolffian Duct Adenoma:

Name: Wolffian Duct Adenoma 12 15
Mesonephroma, Benign 12 71
Benign Mesonephroma 12
Mesonephric Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2616
NCIt 49 C4294
SNOMED-CT 67 72889001
UMLS 71 C0334530

Summaries for Wolffian Duct Adenoma

Disease Ontology : 12 A reproductive organ benign neoplasm that derives from glandular epithelial cells and that is located in the region of the Wolffian duct.

MalaCards based summary : Wolffian Duct Adenoma, also known as mesonephroma, benign, is related to urethra adenocarcinoma and rete testis adenoma. An important gene associated with Wolffian Duct Adenoma is PAX2 (Paired Box 2), and among its related pathways/superpathways are Primary Focal Segmental Glomerulosclerosis FSGS and ID signaling pathway. Affiliated tissues include region of the wolffian duct.

Related Diseases for Wolffian Duct Adenoma

Diseases related to Wolffian Duct Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 urethra adenocarcinoma 10.2 PAX8 PAX2
2 rete testis adenoma 10.2 PAX8 PAX2
3 male urethral cancer 10.1 KLK3 AMACR
4 ureterocele 10.1 PAX8 PAX2
5 adenosquamous prostate carcinoma 10.1 KLK3 AMACR
6 wilms tumor 5 10.1 PAX8 PAX2
7 adenoma 10.0
8 mucinous adenocarcinoma 10.0 KRT7 AMACR
9 ovarian mucinous adenocarcinoma 10.0 KRT7 AMACR
10 ovarian mesodermal adenosarcoma 10.0 PAX8 KRT7
11 seminal vesicle adenocarcinoma 10.0 KRT7 KLK3
12 rete testis neoplasm 10.0 PAX8 KRT7
13 papillary adenoma 10.0 KRT7 AMACR
14 rete testis adenocarcinoma 10.0 PAX8 KRT7
15 cystitis cystica 10.0 KRT7 KLK3
16 ovarian seromucinous carcinoma 10.0 PAX8 KRT7
17 renal pelvis adenocarcinoma 10.0 PAX8 KRT7
18 submandibular gland cancer 10.0 KRT7 KLK3
19 benign mesothelioma 10.0 PAX8 KRT7
20 metanephric adenoma 10.0 KRT7 AMACR
21 epithelial predominant wilms' tumor 10.0 KRT7 AMACR
22 ovarian mucinous neoplasm 10.0 PAX8 KRT7
23 thymus clear cell carcinoma 10.0 PAX8 KRT7
24 thyroid angiosarcoma 10.0 PAX8 KRT7
25 prostate neuroendocrine neoplasm 10.0 KRT7 KLK3
26 urinary tract obstruction 10.0 PAX2 KLK3
27 renal hypodysplasia/aplasia 1 9.9 PAX8 PAX2
28 ovarian benign neoplasm 9.9 PAX8 KRT7
29 cervix endometriosis 9.9 PAX2 MME
30 epithelioid cell synovial sarcoma 9.9 PAX8 KRT7
31 peritoneum cancer 9.9 PAX8 KRT7
32 female reproductive endometrioid cancer 9.9 PAX8 KRT7
33 endocervical carcinoma 9.9 PAX8 KRT7
34 papillary serous adenocarcinoma 9.9 PAX8 KRT7
35 spindle cell carcinoma 9.9 KRT7 AMACR
36 thymic carcinoma 9.8 PAX8 KRT7
37 primary cutaneous amyloidosis 9.8 KRT7 KLK3
38 hidradenoma 9.8 MME KRT7
39 urethra cancer 9.8 PAX8 PAX2 KLK3
40 adenofibroma 9.8 MME KRT7
41 subareolar duct papillomatosis 9.8 MME KRT7
42 nipple neoplasm 9.8 MME KRT7
43 small cell carcinoma 9.8 KRT7 KLK3
44 mixed epithelial stromal tumour 9.8 MME KRT7
45 cervical adenoma malignum 9.7 MME KRT7
46 eccrine papillary adenocarcinoma 9.7 MME KRT7
47 eccrine sweat gland neoplasm 9.7 MME KRT7
48 prostatic acinar adenocarcinoma 9.7 PAX8 KLK3 AMACR
49 sweat gland neoplasm 9.7 MME KRT7
50 balloon cell malignant melanoma 9.7 MME KRT7

Graphical network of the top 20 diseases related to Wolffian Duct Adenoma:



Diseases related to Wolffian Duct Adenoma

Symptoms & Phenotypes for Wolffian Duct Adenoma

Drugs & Therapeutics for Wolffian Duct Adenoma

Search Clinical Trials , NIH Clinical Center for Wolffian Duct Adenoma

Genetic Tests for Wolffian Duct Adenoma

Anatomical Context for Wolffian Duct Adenoma

The Foundational Model of Anatomy Ontology organs/tissues related to Wolffian Duct Adenoma:

19
Region Of The Wolffian Duct

Publications for Wolffian Duct Adenoma

Articles related to Wolffian Duct Adenoma:

# Title Authors PMID Year
1
Mesonephric adenoma in remnant ureteric stump: A rare entity. 61
21716880 2011
2
Nephrogenic metaplasia of urinary bladder--a case report. 61
16295498 2004

Variations for Wolffian Duct Adenoma

Expression for Wolffian Duct Adenoma

Search GEO for disease gene expression data for Wolffian Duct Adenoma.

Pathways for Wolffian Duct Adenoma

Pathways related to Wolffian Duct Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.82 PAX2 MME
2 9.83 PAX8 PAX2

GO Terms for Wolffian Duct Adenoma

Biological processes related to Wolffian Duct Adenoma according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 inner ear morphogenesis GO:0042472 9.58 PAX2 PAX8
2 branching involved in ureteric bud morphogenesis GO:0001658 9.57 PAX8 PAX2
3 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.56 PAX8 PAX2
4 urogenital system development GO:0001655 9.55 PAX8 PAX2
5 mesonephros development GO:0001823 9.54 PAX8 PAX2
6 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.52 PAX8 PAX2
7 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.51 PAX8 PAX2
8 pronephros development GO:0048793 9.49 PAX8 PAX2
9 metanephric epithelium development GO:0072207 9.48 PAX8 PAX2
10 metanephric nephron tubule formation GO:0072289 9.46 PAX8 PAX2
11 metanephric distal convoluted tubule development GO:0072221 9.43 PAX8 PAX2
12 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.4 PAX8 PAX2
13 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.37 PAX8 PAX2
14 positive regulation of metanephric DCT cell differentiation GO:2000594 9.32 PAX8 PAX2
15 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.26 PAX8 PAX2
16 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.16 PAX8 PAX2
17 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 8.96 PAX8 PAX2
18 pronephric field specification GO:0039003 8.62 PAX8 PAX2

Molecular functions related to Wolffian Duct Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endopeptidase activity GO:0004175 8.62 MME KLK3

Sources for Wolffian Duct Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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