Aliases & Classifications for Writing Disorder

MalaCards integrated aliases for Writing Disorder:

Name: Writing Disorder 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0060047
UMLS 70 C0860614

Summaries for Writing Disorder

Disease Ontology : 12 A learning disability that involves impaired written language ability such as impairments in handwriting, spelling, organization of ideas, and composition.

MalaCards based summary : Writing Disorder is related to agraphia and apraxia, and has symptoms including aprosodia An important gene associated with Writing Disorder is GRN (Granulin Precursor), and among its related pathways/superpathways is Pathways of neurodegeneration - multiple diseases. Affiliated tissues include brain and bone, and related phenotypes are behavior/neurological and cellular

Related Diseases for Writing Disorder

Diseases related to Writing Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 agraphia 30.9 VCP TARDBP PRNP MAPT GRN C9orf72
2 apraxia 30.1 MAPT GRN C9orf72
3 learning disability 29.5 MAPT KIAA0319 DNAAF4 DCDC2 CEBPD
4 reading disorder 29.3 KIAA0319 DNAAF4 DCDC2 CEBPD
5 dyslexia 29.2 KIAA0319 DNAAF4 DCDC2 CEBPD
6 dysgraphia 28.1 ZNF74 TARDBP MAPT LINC00159 KIAA0319 HYPK
7 apperceptive agnosia 10.3 GRN C9orf72
8 visual agnosia 10.3 MAPT GRN
9 amusia 10.3 GRN DCDC2
10 simultanagnosia 10.3 TARDBP MAPT
11 amyotrophic lateral sclerosis type 15 10.2 CHMP2B C9orf72
12 postencephalitic parkinson disease 10.2 TARDBP MAPT
13 phonagnosia 10.2 CEBPD C9orf72
14 epilepsy, idiopathic generalized 2 10.2 TARDBP MAPT C9orf72
15 arteriolosclerosis 10.2 TARDBP MAPT
16 amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 10.2 TARDBP MAPT C9orf72
17 early-onset, autosomal dominant alzheimer disease 10.1 VCP MAPT GRN
18 gerstmann syndrome 10.1 PRNP MAPT GRN
19 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 10.1 PRNP MAPT GRN
20 akinetic mutism 10.1 TARDBP PRNP MAPT
21 inclusion body myositis 10.1 VCP TARDBP MAPT
22 frontotemporal dementia and/or amyotrophic lateral sclerosis 2 10.1 FUS C9orf72
23 locked-in syndrome 10.1 TARDBP FUS
24 amyotrophic lateral sclerosis 6 with or without frontotemporal dementia 10.1 VCP FUS
25 progressive bulbar palsy 10.1 FUS C9orf72
26 echolalia 10.1 MAPT GRN CEBPD C9orf72
27 amyotrophic lateral sclerosis 18 10.0 FUS CHMP2B
28 amyotrophic lateral sclerosis type 22 10.0 TARDBP FUS C9orf72
29 frontotemporal dementia and/or amyotrophic lateral sclerosis 3 10.0 TARDBP FUS C9orf72
30 spinal muscular atrophy, distal, autosomal recessive, 4 10.0 TARDBP FUS C9orf72
31 amyotrophic lateral sclerosis 4, juvenile 10.0 TARDBP FUS C9orf72
32 dermatopathia pigmentosa reticularis 10.0 TARDBP FUS C9orf72
33 spinocerebellar ataxia 2 10.0 TARDBP FUS C9orf72
34 amyotrophic lateral sclerosis 11 10.0 TARDBP FUS CHMP2B
35 spinal and bulbar muscular atrophy, x-linked 1 10.0 TARDBP FUS C9orf72
36 essential tremor 10.0 MAPT FUS C9orf72
37 amyotrophic lateral sclerosis type 12 10.0 TARDBP FUS CHMP2B
38 asperger syndrome 10.0
39 dyslexia 2 10.0 KIAA0319 DCDC2
40 amyotrophic lateral sclerosis type 14 10.0 VCP FUS CHMP2B
41 amyotrophic lateral sclerosis 16, juvenile 10.0 VCP FUS CHMP2B
42 developmental coordination disorder 9.9 CEBPD ABCB10
43 cerebellar disease 9.9 MAPT FUS C9orf72
44 semantic dementia 9.9 TARDBP MAPT GRN CHMP2B C9orf72
45 prosopagnosia 9.9 TARDBP MAPT GRN CHMP2B C9orf72
46 mutism 9.9 TARDBP MAPT GRN CHMP2B C9orf72
47 giant axonal neuropathy 2 9.9 TARDBP FUS
48 muscular atrophy 9.9 TARDBP MAPT FUS C9orf72
49 pica disease 9.9 TARDBP MAPT FUS C9orf72
50 progressive non-fluent aphasia 9.9 VCP MAPT GRN CHMP2B C9orf72

Graphical network of the top 20 diseases related to Writing Disorder:



Diseases related to Writing Disorder

Symptoms & Phenotypes for Writing Disorder

UMLS symptoms related to Writing Disorder:


aprosodia

MGI Mouse Phenotypes related to Writing Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.85 C9orf72 CEBPD DCDC2 DNAAF4 GRN KIAA0319
2 cellular MP:0005384 9.65 ABCB10 C9orf72 CEBPD DNAAF4 GRN KIAA0319
3 nervous system MP:0003631 9.32 C9orf72 CHMP2B DCDC2 DNAAF4 GRN KIAA0319

Drugs & Therapeutics for Writing Disorder

Search Clinical Trials , NIH Clinical Center for Writing Disorder

Genetic Tests for Writing Disorder

Anatomical Context for Writing Disorder

MalaCards organs/tissues related to Writing Disorder:

40
Brain, Bone

Publications for Writing Disorder

Articles related to Writing Disorder:

(show all 34)
# Title Authors PMID Year
1
Reading-writing disorder in children with idiopathic epilepsy. 61
32563891 2020
2
Writing errors in primary progressive aphasia. 61
32905710 2020
3
Non-linear spelling in writing after a pure cerebellar lesion. 61
31302109 2019
4
Attitudes and knowledge of parents of preschool children about specific learning disabilities. 61
28953831 2017
5
DCDC2 gene polymorphisms are associated with developmental dyslexia in Chinese Uyghur children. 61
28400808 2017
6
Variability of writing disorders in Wernicke's aphasia underperforming different writing tasks: A single-case study. 61
27061639 2016
7
Apraxic agraphia following thalamic damage: Three new cases. 61
26460984 2015
8
Apraxic agraphia following bithalamic damage. 61
25682350 2015
9
[Reading and writing disorder (RWD) - criteria for a speech therapist intervention]. 61
24676870 2014
10
Brainstem arteriovenous malformation presenting with dyspraxic handwriting in a young girl. 61
23911278 2014
11
Expressive writing in people with traumatic brain injury and learning disability. 61
24284454 2014
12
Development of visual-motor perception in pupils with expressive writing disorder and pupils without expressive writing disorder: a comparative statistical analysis. 61
24791121 2013
13
[Neurolinguistic features during recovery of a Chinese patient with pure alexia]. 61
23688992 2013
14
"Apraxic dysgraphia" in a 15-year-old left-handed patient: disruption of the cerebello-cerebral network involved in the planning and execution of graphomotor movements. 61
22752975 2013
15
[Prediction of learning disability at school by means of SOPESS]. 61
22009299 2011
16
Cerebellar-induced apraxic agraphia: a review and three new cases. 61
21507544 2011
17
Reading comprehension, word decoding and spelling in girls with autism spectrum disorders (ASD) or attention-deficit/hyperactivity disorder (AD/HD): performance and predictors. 61
19343578 2010
18
The role of gene DCDC2 in German dyslexics. 61
19238550 2009
19
Long-term psychosocial and health economy consequences of ADHD, autism, and reading-writing disorder: a prospective service evaluation project. 61
17968030 2008
20
ADHD and dysgraphia: underlying mechanisms. 61
17710822 2007
21
Dysexecutive agraphia: a major executive dysfunction sign. 61
16644524 2006
22
Writing through the phonological buffer: a case of progressive writing disorder. 61
15949512 2005
23
The evolution of dysgraphia in Alzheimer's disease. 61
15121235 2004
24
Vowels in the buffer: a case study of acquired dysgraphia with selective vowel substitutions. 61
20957567 2003
25
[Developmental expressive writing disorder]. 61
14503326 2003
26
[Dyslexia. Bases of reading. Reading-writing disorder. Ocular reading disorder]. 61
11917807 2002
27
Neurocognitive stability in Asperger syndrome, ADHD, and reading and writing disorder: a pilot study. 61
11263686 2001
28
[Writing disorder using a word processor: role of the left hand]. 61
10637923 1999
29
[Neuropsychological approach to the learning disability: the correlation between neuropsychological findings and rCBF]. 61
10355263 1999
30
Selective kana jargonagraphia following right hemispheric infarction. 61
9642020 1998
31
Spatial dysgraphia and cerebellar lesion: a case report. 61
9191761 1997
32
[Two cases of pure agraphia developed after thalamic hemorrhage]. 61
1863484 1991
33
A model of writing performance: evidence from a dysgraphic patient with an "allographic" writing disorder. 61
4041261 1985
34
Reading, writing and drawing disorder due to right brain damage. 61
7349010 1980

Variations for Writing Disorder

Expression for Writing Disorder

Search GEO for disease gene expression data for Writing Disorder.

Pathways for Writing Disorder

Pathways related to Writing Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.35 VCP TARDBP PRNP MAPT FUS CHMP2B

GO Terms for Writing Disorder

Cellular components related to Writing Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 9.46 PRNP MAPT FUS C9orf72
2 cytoplasmic stress granule GO:0010494 9.13 VCP TARDBP C9orf72
3 main axon GO:0044304 8.62 MAPT C9orf72

Biological processes related to Writing Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homooligomerization GO:0051260 9.33 PRNP MAPT FUS
2 stress granule assembly GO:0034063 9.26 MAPT C9orf72
3 neuron migration GO:0001764 9.13 KIAA0319 DNAAF4 DCDC2
4 negative regulation of protein phosphorylation GO:0001933 8.8 TARDBP PRNP C9orf72

Molecular functions related to Writing Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 8.8 PRNP MAPT GRN

Sources for Writing Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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