Aliases & Classifications for Writing Disorder

MalaCards integrated aliases for Writing Disorder:

Name: Writing Disorder 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0060047
UMLS 73 C0860614

Summaries for Writing Disorder

Disease Ontology : 12 A learning disability that involves impaired written language ability such as impairments in handwriting, spelling, organization of ideas, and composition.

MalaCards based summary : Writing Disorder is related to dysgraphia and agraphia, and has symptoms including aprosodia An important gene associated with Writing Disorder is DCDC2 (Doublecortin Domain Containing 2). The drugs Omega 3 Fatty Acid and Olive have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotypes are Decreased viability with TRAIL and behavior/neurological

Related Diseases for Writing Disorder

Diseases related to Writing Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 dysgraphia 31.8 MAP4K5 PSEN1 SLC17A5
2 agraphia 31.4 GRN PSEN1 TARDBP
3 aphasia 29.6 GRN PSEN1
4 expressive language disorder 10.0 PSEN1 TARDBP
5 reading disorder 10.0 DCDC2 PSEN1
6 alexia 10.0 PSEN1 TARDBP
7 progressive non-fluent aphasia 9.9 GRN PSEN1
8 nervous system disease 9.9 PSEN1 TARDBP
9 behavioral variant of frontotemporal dementia 9.9 GRN PSEN1
10 prosopagnosia 9.9 GRN PSEN1
11 gait apraxia 9.9 GRN PSEN1
12 apraxia 9.9 GRN PSEN1
13 echolalia 9.9 GRN PSEN1
14 central nervous system disease 9.9 PSEN1 TARDBP
15 visual agnosia 9.9 GRN PSEN1
16 perry syndrome 9.8 GRN TARDBP
17 alzheimer disease 9.8
18 autism 9.8
19 asperger syndrome 9.8
20 dyslexia 9.8
21 speech disorder 9.8 GRN SLC17A5
22 specific developmental disorder 9.8 DCDC2 GRN PSEN1
23 phonagnosia 9.7 GRN PSEN1 TARDBP
24 associative agnosia 9.7 GRN PSEN1 TARDBP
25 nominal aphasia 9.7 GRN PSEN1 TARDBP
26 semantic dementia 9.7 GRN PSEN1 TARDBP
27 dementia 9.7 GRN PSEN1 TARDBP
28 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 9.7 GRN PSEN1 TARDBP
29 frontotemporal dementia 9.7 GRN PSEN1 TARDBP
30 amyotrophic lateral sclerosis 1 9.7 GRN PSEN1 TARDBP
31 pick disease of brain 9.7 GRN PSEN1 TARDBP
32 supranuclear palsy, progressive, 1 9.7 GRN PSEN1 TARDBP
33 dementia, lewy body 9.7 GRN PSEN1 TARDBP
34 speech and communication disorders 9.7 GRN PSEN1 TARDBP
35 disease of mental health 9.7 GRN PSEN1 TARDBP
36 motor neuron disease 9.7 GRN TARDBP

Graphical network of the top 20 diseases related to Writing Disorder:



Diseases related to Writing Disorder

Symptoms & Phenotypes for Writing Disorder

UMLS symptoms related to Writing Disorder:


aprosodia

GenomeRNAi Phenotypes related to Writing Disorder according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with TRAIL GR00240-S-2 8.62 GRN MAP4K5

MGI Mouse Phenotypes related to Writing Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.63 DCDC2 GRN MAP4K5 PSEN1 SLC17A5 TARDBP
2 cellular MP:0005384 9.35 GRN MAP4K5 PSEN1 SLC17A5 TARDBP
3 nervous system MP:0003631 9.02 DCDC2 GRN PSEN1 SLC17A5 TARDBP

Drugs & Therapeutics for Writing Disorder

Drugs for Writing Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Omega 3 Fatty Acid Phase 3
2 Olive Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents Completed NCT01219309 Phase 3

Search NIH Clinical Center for Writing Disorder

Genetic Tests for Writing Disorder

Anatomical Context for Writing Disorder

MalaCards organs/tissues related to Writing Disorder:

41
Brain

Publications for Writing Disorder

Articles related to Writing Disorder:

# Title Authors Year
1
Development of visual-motor perception in pupils with expressive writing disorder and pupils without expressive writing disorder: a comparative statistical analysis. ( 24791121 )
2013
2
Long-term psychosocial and health economy consequences of ADHD, autism, and reading-writing disorder: a prospective service evaluation project. ( 17968030 )
2008
3
Writing through the phonological buffer: a case of progressive writing disorder. ( 15949512 )
2005
4
Neurocognitive stability in Asperger syndrome, ADHD, and reading and writing disorder: a pilot study. ( 11263686 )
2001
5
A model of writing performance: evidence from a dysgraphic patient with an "allographic" writing disorder. ( 4041261 )
1985

Variations for Writing Disorder

Expression for Writing Disorder

Search GEO for disease gene expression data for Writing Disorder.

Pathways for Writing Disorder

GO Terms for Writing Disorder

Biological processes related to Writing Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron migration GO:0001764 9.16 DCDC2 PSEN1
2 negative regulation of protein phosphorylation GO:0001933 8.96 PSEN1 TARDBP
3 intracellular signal transduction GO:0035556 8.8 DCDC2 MAP4K5 PSEN1

Sources for Writing Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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