CX
MCID: XNT002
MIFTS: 36

Xanthogranulomatous Cholecystitis (CX)

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Xanthogranulomatous Cholecystitis

MalaCards integrated aliases for Xanthogranulomatous Cholecystitis:

Name: Xanthogranulomatous Cholecystitis 12 53 44 15 73
Cx 53 3

Classifications:



External Ids:

Disease Ontology 12 DOID:9766
MeSH 44 C536762
NCIt 50 C35792
UMLS 73 C1337035

Summaries for Xanthogranulomatous Cholecystitis

CDC : 3 0 0 0 0 0 0 0

MalaCards based summary : Xanthogranulomatous Cholecystitis, also known as cx, is related to cholecystitis and gallbladder cancer. An important gene associated with Xanthogranulomatous Cholecystitis is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Hexose transport and Hematopoietic cell lineage. Affiliated tissues include liver, colon and brain.

Related Diseases for Xanthogranulomatous Cholecystitis

Diseases related to Xanthogranulomatous Cholecystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 cholecystitis 11.0
2 gallbladder cancer 10.6
3 bartholin's duct cyst 10.3 SMUG1 TP53
4 adenocarcinoma 10.3
5 cellular ependymoma 10.3 SMUG1 TP53
6 protoplasmic astrocytoma 10.3 SMUG1 TP53
7 colloid adenoma 10.3 SMUG1 TP53
8 ovarian squamous cell carcinoma 10.3 SLC2A1 SMUG1
9 metal allergy 10.3 CD4 CD8A
10 atrophy of prostate 10.3 SLC2A1 TP53
11 pulmonary artery leiomyosarcoma 10.2 CD68 SMUG1
12 gallbladder adenocarcinoma 10.2
13 sternum cancer 10.2 CD68 SMUG1
14 mature teratoma 10.2 SMUG1 TP53
15 polyclonal hypergammaglobulinemia 10.2 CD4 CD8A LYZ
16 brain sarcoma 10.1 CD68 SMUG1
17 liver lymphoma 10.1 CEACAM5 SMUG1
18 intracranial chondrosarcoma 10.1 CEACAM5 TP53
19 splenic tuberculosis 10.1 CEACAM5 SMUG1
20 gallbladder squamous cell carcinoma 10.1 CEACAM5 SMUG1
21 malignant acrospiroma 10.1 CEACAM5 SMUG1
22 dermis tumor 10.1 LYZ SERPINA3
23 central nervous system sarcoma 10.1 CD68 LYZ
24 cardiomyopathy, infantile histiocytoid 10.1 CD68 LYZ
25 malignant giant cell tumor of soft parts 10.1 CD68 LYZ
26 bladder carcinoma in situ 10.1 CD68 TP53
27 adenosquamous gallbladder carcinoma 10.1 CEACAM5 SERPINA3
28 tolosa-hunt syndrome 10.1 CEACAM5 SMUG1
29 fibroepithelial basal cell carcinoma 10.1 CEACAM5 TP53
30 in situ pulmonary adenocarcinoma 10.1 LYZ S100A9 SMUG1
31 inflammatory mfh 10.1 CD68 SERPINA3
32 atypical follicular adenoma 10.1 CEACAM5 TP53
33 scrotal carcinoma 10.1 CD68 SERPINA3 TP53
34 malignant spiradenoma 10.1 CEACAM5 SMUG1 TP53
35 mirizzi syndrome 10.1
36 melkersson-rosenthal syndrome 10.1 CD4 CD68 CD8A
37 lactocele 10.1 CD68 SMUG1
38 prostate squamous cell carcinoma 10.1 CEACAM5 SMUG1 TP53
39 hematocele of tunica vaginalis testis 10.1 CEACAM5 F10
40 gallbladder disease 10.1 CDO1 CEACAM5 TP53
41 esophageal disease 10.1 CEACAM5 SMUG1 TP53
42 retinal hemangioblastoma 10.1 LYZ S100A9 SERPINA3
43 ulcerative stomatitis 10.1 CD68 LYZ TP53
44 meningioma, familial 10.1 CD68 SMUG1 TP53
45 rectal neoplasm 10.1 CEACAM5 SMUG1 TP53
46 granulomatous myositis 10.1 CD68 LYZ SMUG1
47 respiratory system cancer 10.1 CEACAM5 SMUG1 TP53
48 intestinal disease 10.1 CEACAM5 SMUG1 TP53
49 lymphatic system disease 10.1 CD68 LYZ SMUG1
50 respiratory system disease 10.0 CEACAM5 SMUG1 TP53

Graphical network of the top 20 diseases related to Xanthogranulomatous Cholecystitis:



Diseases related to Xanthogranulomatous Cholecystitis

Symptoms & Phenotypes for Xanthogranulomatous Cholecystitis

Drugs & Therapeutics for Xanthogranulomatous Cholecystitis

Search Clinical Trials , NIH Clinical Center for Xanthogranulomatous Cholecystitis

Cochrane evidence based reviews: xanthogranulomatous cholecystitis

Genetic Tests for Xanthogranulomatous Cholecystitis

Anatomical Context for Xanthogranulomatous Cholecystitis

MalaCards organs/tissues related to Xanthogranulomatous Cholecystitis:

41
Liver, Colon, Brain, Prostate, Pancreas, Testis, Thymus

Publications for Xanthogranulomatous Cholecystitis

Articles related to Xanthogranulomatous Cholecystitis:

(show top 50) (show all 386)
# Title Authors Year
1
A Rare Pathology of Difficult Laparoscopic Cholecystectomy: Xanthogranulomatous Cholecystitis. ( 29615182 )
2018
2
Diagnostic accuracy of MDCT in differentiating gallbladder cancer from acute and xanthogranulomatous cholecystitis. ( 29679780 )
2018
3
Diffuse Xanthogranulomatous Cholecystitis: Master of Disguise. ( 29922533 )
2018
4
Xanthogranulomatous cholecystitis shows overlapping histological features with IgG4-related cholecystitis. ( 29023932 )
2018
5
Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma. ( 30316146 )
2018
6
CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. ( 30142881 )
2018
7
Clinical Outcomes of Elective Laparoscopic Cholecystectomy: Retrospective Comparative Study Between Patients With and Without Xanthogranulomatous Cholecystitis. ( 30516720 )
2018
8
Rare cause of gastric outlet obstruction: xanthogranulomatous cholecystitis. ( 30206069 )
2018
9
CX-4945, a Selective Inhibitor of Casein Kinase 2, Synergizes with B Cell Receptor Signaling Inhibitors in Inducing Diffuse Large B Cell Lymphoma Cell Death. ( 28460620 )
2018
10
Casein Kinase 2 Inhibitor, CX-4945, as a Potential Targeted Anticancer Agent in Gastric Cancer. ( 30396934 )
2018
11
Synergistic therapeutic effect of diethylstilbestrol and CX-4945 in human acute T-lymphocytic leukemia cells. ( 29275177 )
2018
12
Establishment of a Mucin Secreting Cell Line Cx-03 from an Uterine Carcino Sarcoma. ( 30411161 )
2018
13
Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-κB and MAPK signalling pathways. ( 29475099 )
2018
14
CX-3543 Promotes Cell Apoptosis through Downregulation of CCAT1 in Colon Cancer Cells. ( 30519593 )
2018
15
Combination of the low anticoagulant heparin CX-01 with chemotherapy for the treatment of acute myeloid leukemia. ( 29467192 )
2018
16
Novel water-soluble lignin derivative BP-Cx-1: identification of components and screening of potential targets in silico and in vitro. ( 29719628 )
2018
17
Purification and characterization of two novel peroxidases from the dye-decolorizing fungus Bjerkandera adusta strain CX-9. ( 28813685 )
2018
18
Revelation of susceptibility differences due to Hg(II) accumulation in Streptococcus pyogenes against CX-AgNPs and Cefixime by atomic force microscopy. ( 28822261 )
2018
19
Impact of RNA polymerase I inhibitor CX-5461 on viral kinase-dependent and -independent cytomegalovirus replication. ( 29458130 )
2018
20
First Record of Culex (Microculex) daumastocampa (Diptera: Culicidae) in Mexico, with Notes on Cx. rejector and Cx. imitator. ( 29520575 )
2018
21
Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461. ( 29631594 )
2018
22
Inhibition of interleukin 8/C‑X-C chemokine receptor 1,/2 signaling reduces malignant features in human pancreatic cancer cells. ( 29749433 )
2018
23
Molecular study of Cw /Cx antigens and frequency of Rh phenotypes in southeast Brazilian blood donors. ( 29926983 )
2018
24
Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor. ( 30016731 )
2018
25
CX-5461-loaded nucleolus-targeting nanoplatform for cancer therapy through induction of pro-death autophagy. ( 30172068 )
2018
26
The Selective RNA Polymerase I Inhibitor CX-5461 Mitigates Neointimal Remodeling in a Modified Model of Rat Aortic Transplantation. ( 30247451 )
2018
27
Infiltrative xanthogranulomatous cholecystitis mimicking aggressive gallbladder carcinoma: A diagnostic and therapeutic dilemma. ( 29358875 )
2017
28
Computed Tomography (CT) and Magnetic Resonance (MR) Findings in Xanthogranulomatous Cholecystitis: Retrospective Analysis of Pathologically Proven 30 Cases - Tertiary Care Experience. ( 28685006 )
2017
29
Xanthogranulomatous Cholecystitis: Analysis of 108 Patients. ( 29217901 )
2017
30
Xanthogranulomatous cholecystitis: Is an initial laparoscopic approach feasible? ( 28593410 )
2017
31
Xanthogranulomatous Cholecystitis with Florid Ducts of Luschka: Double Trouble Mimicking Malignancy. ( 28658786 )
2017
32
Strategies for Differentiating Gallbladder Carcinoma from Xanthogranulomatous Cholecystitis-a Tertiary Care Centre Experience. ( 29203989 )
2017
33
miR-139 acts as a tumor suppressor in T-cell acute lymphoblastic leukemia by targeting CX chemokine receptor 4. ( 28979681 )
2017
34
CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells. ( 27758824 )
2017
35
CX, DPX, and PCW: Web Servers for the Visualization of Interior and Protruding Regions of Protein Structures in 3D and 1D. ( 27787834 )
2017
36
Therapeutic Targeting of RNA Polymerase I With the Small-Molecule CX-5461 for Prevention of Arterial Injury-Induced Neointimal Hyperplasia. ( 28062495 )
2017
37
Autophagy Induced by CX-4945, a Casein Kinase 2 Inhibitor, Enhances Apoptosis in Pancreatic Cancer Cell Lines. ( 28196025 )
2017
38
Targeting Protein Kinase CK2: Evaluating CX-4945 Potential for GL261 Glioblastoma Therapy in Immunocompetent Mice. ( 28208677 )
2017
39
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. ( 28211448 )
2017
40
RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma. ( 28369725 )
2017
41
Culex (Culiciomyia) sasai (Diptera: Culicidae), senior synonym of Cx. spiculothorax and a new country record for Bhutan. ( 28414028 )
2017
42
STEMI with fluctuating closing of LAD and Cx: Do not concentrate on the finger. ( 28499664 )
2017
43
CX-4945: the protein kinase CK2 inhibitor and anti-cancer drug shows anti-fungal activity. ( 28501934 )
2017
44
Reduced productivity of Culex pipiens and Cx. restuans (Diptera: Culicidae) mosquitoes in parking area catch basins in the northeast Chicago metropolitan area. ( 28504453 )
2017
45
Activation of sodium persulfate by magnetic carbon xerogels (CX/CoFe) for the oxidation of bisphenol A: Process variables effects, matrix effects and reaction pathways. ( 28750289 )
2017
46
Combining cryo-electron microscopy (cryo-EM) and cross-linking mass spectrometry (CX-MS) for structural elucidation of large protein assemblies. ( 29080436 )
2017
47
Performance Monitoring of Chilled-Water Distribution Systems Using HVAC-Cx. ( 29167584 )
2017
48
Morphological redescription of <i>Culex</i> (Microculex) davisi and <i>Cx</i>. (<i>Mcx</i>.) <i>imitator</i> (Diptera: Culicidae) including structures and stages not previously described. ( 29245606 )
2017
49
Aberrant Expression of Cx Isoforms in the Adult Caput Epididymis exposed to Estradiol Benzoate or Flutamide at the Weaning. ( 29354784 )
2017
50
Xanthogranulomatous cholecystitis: contrast-enhanced ultrasound features and differential diagnosis from wall-thickening gallbladder carcinoma. ( 27011044 )
2016

Variations for Xanthogranulomatous Cholecystitis

Expression for Xanthogranulomatous Cholecystitis

Search GEO for disease gene expression data for Xanthogranulomatous Cholecystitis.

Pathways for Xanthogranulomatous Cholecystitis

GO Terms for Xanthogranulomatous Cholecystitis

Cellular components related to Xanthogranulomatous Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.56 CD4 CD8A CXCR6 ITGAM
2 integral component of plasma membrane GO:0005887 9.5 BTLA CD4 CD8A CEACAM5 CXCR6 SLC2A1
3 plasma membrane GO:0005886 9.44 BTLA CD4 CD68 CD8A CEACAM5 CXCL16
4 T cell receptor complex GO:0042101 9.16 CD4 CD8A

Biological processes related to Xanthogranulomatous Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.8 BTLA CD4 CD8A ITGAM S100A9
2 inflammatory response GO:0006954 9.72 CDO1 CXCR6 LYZ S100A9 SERPINA3
3 neutrophil degranulation GO:0043312 9.43 CD68 ITGAM LYZ S100A9 SERPINA3 SLC2A3
4 L-ascorbic acid metabolic process GO:0019852 9.37 SLC2A1 SLC2A3
5 carbohydrate transport GO:0008643 9.33 SLC2A1 SLC2A14 SLC2A3
6 dehydroascorbic acid transport GO:0070837 9.26 SLC2A1 SLC2A3
7 glucose transmembrane transport GO:1904659 8.8 SLC2A1 SLC2A14 SLC2A3

Molecular functions related to Xanthogranulomatous Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane transporter activity GO:0022857 9.5 SLC2A1 SLC2A14 SLC2A3
2 coreceptor activity GO:0015026 9.33 CD4 CD8A CXCR6
3 dehydroascorbic acid transmembrane transporter activity GO:0033300 9.26 SLC2A1 SLC2A3
4 glucose transmembrane transporter activity GO:0005355 9.13 SLC2A1 SLC2A14 SLC2A3
5 D-glucose transmembrane transporter activity GO:0055056 8.8 SLC2A1 SLC2A14 SLC2A3

Sources for Xanthogranulomatous Cholecystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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