MCID: XNT001
MIFTS: 30

Xanthogranulomatous Pyelonephritis

Categories: Nephrological diseases

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

MalaCards integrated aliases for Xanthogranulomatous Pyelonephritis:

Name: Xanthogranulomatous Pyelonephritis 12 15 17
Pyelonephritis, Xanthogranulomatous 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11401
MeSH 44 D011705
NCIt 50 C123038
SNOMED-CT 67 197777006
UMLS 70 C0034188

Summaries for Xanthogranulomatous Pyelonephritis

MalaCards based summary : Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to pyelonephritis and chronic pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is EGF (Epidermal Growth Factor), and among its related pathways/superpathways are Folate Metabolism and Lung fibrosis. Affiliated tissues include kidney, colon and liver, and related phenotype is immune system.

Related Diseases for Xanthogranulomatous Pyelonephritis

Diseases related to Xanthogranulomatous Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 290)
# Related Disease Score Top Affiliating Genes
1 pyelonephritis 32.1 CRP CCL2
2 chronic pyelonephritis 31.1 SERPINA3 CRP
3 hydronephrosis 30.7 EGF CRP CCL2
4 acute cystitis 30.6 SERPINA3 CRP CCL2
5 urinary tract obstruction 30.6 EGF CRP CCL2
6 bacteriuria 30.3 CRP CCL2
7 ileus 30.1 CRP CCL2
8 actinomycosis 30.0 CRP CD68
9 pyelitis 29.8 SERPINA3 CRP
10 appendicitis 29.8 CRP CCL2
11 periodontitis 29.6 SERPINA3 CRP CCL2
12 sarcoidosis 1 29.5 SERPINA3 CRP CCL2
13 bronchopneumonia 29.5 SERPINA3 CRP CD68
14 eye disease 29.2 SERPINA3 EGF CRP CCL2
15 urinary tract infection 10.8
16 renal cell carcinoma, nonpapillary 10.7
17 nephrolithiasis 10.7
18 urolithiasis 10.6
19 pyuria 10.6
20 kidney cancer 10.5
21 amyloidosis 10.5
22 renal tuberculosis 10.5
23 lipomatosis 10.4
24 malakoplakia 10.4
25 squamous cell carcinoma 10.4
26 transitional cell carcinoma 10.4
27 interstitial nephritis 10.4
28 horseshoe kidney 10.3
29 nephrolithiasis, calcium oxalate 10.3
30 renal cell carcinoma, papillary, 1 10.3
31 disease by infectious agent 10.3
32 nephrotic syndrome 10.3
33 kidney disease 10.3
34 chromophil renal cell carcinoma 10.3
35 sebaceous adenoma 10.2 SERPINA3 EGF
36 renal fibrosis 10.2
37 splenic abscess 10.2
38 acute kidney failure 10.2
39 clear cell renal cell carcinoma 10.2
40 ureteral obstruction 10.2
41 pulmonary embolism 10.2
42 megalocytic interstitial nephritis 10.2
43 back pain 10.2
44 posttransplant acute limbic encephalitis 10.2
45 erdheim-chester disease 10.2 SERPINA3 CCL2
46 trachoma 10.2 SERPINA3 EGF
47 thoracic benign neoplasm 10.2 SERPINA3 EGF
48 breast benign neoplasm 10.2 SERPINA3 EGF
49 breast cyst 10.2 SERPINA3 EGF
50 actinobacillosis 10.2 EGF CD68

Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to Xanthogranulomatous Pyelonephritis

Symptoms & Phenotypes for Xanthogranulomatous Pyelonephritis

MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.1 AOAH CCL2 CD68 CRP EGF TFE3

Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

Search Clinical Trials , NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Cochrane evidence based reviews: pyelonephritis, xanthogranulomatous

Genetic Tests for Xanthogranulomatous Pyelonephritis

Anatomical Context for Xanthogranulomatous Pyelonephritis

MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

40
Kidney, Colon, Liver, Bone, Spinal Cord, Pancreas, Skin

Publications for Xanthogranulomatous Pyelonephritis

Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50) (show all 901)
# Title Authors PMID Year
1
Complicated pyelonephritis associated with chronic renal stone disease. 61
33245481 2021
2
Xanthogranulomatous pyelonephritis: a rare presentation of disbelieved renal cell cancer recurrence after nephron-sparing surgery. 61
33682448 2021
3
Long-Term Antibiotic Treatment Prior to Laparoscopic Nephrectomy for Xanthogranulomatous Pyelonephritis Improves Postoperative Outcomes: Results from a Multicenter Study. 61
33080147 2021
4
Xanthogranulomatous pyelonephritis: an overview and management guide for clinicians. 61
33646035 2021
5
Avoidance of Nephrectomy and Percutaneous Extraction of Retroperitoneal Calculi Secondary to Xanthogranulomatous Pyelonephritis. 61
33309280 2021
6
A case report of complete pathological remission after chemotherapy in a patient with primary renal squamous cell carcinoma. 61
33718101 2021
7
CT and MRI in Urinary Tract Infections: A Spectrum of Different Imaging Findings. 61
33401464 2021
8
Angiomyolipoma of the kidney: from simple hamartoma to complex tumour. 61
33131798 2021
9
Comparison of laparoscopic and hand-assisted laparoscopic nephrectomy for inflammatory renal disease: which is the preferred approach? 61
33633798 2021
10
Rare squamous cell carcinoma of the kidney with concurrent xanthogranulomatous pyelonephritis: A case report and review of the literature. 61
33521318 2021
11
[Renal granulomatous nephritis: Histopathological point of view]. 61
33277052 2020
12
A Very Rare Case of Primary Renal Squamous Cell Carcinoma Presenting With Xanthogranulomatous Pyelonephritis on Radiological Imaging. 61
33282610 2020
13
Xanthogranulomatous pyelonephritis presenting as giant gluteal abscess. 61
33088370 2020
14
Challenges and management of laparoscopic treatment of pyonephrosis caused by calculi. 61
33302927 2020
15
A rare presentation of xanthogranulomatous pyelonephritis and emphysematous pyelonephritis complicated with necrotizing fasciitis of scrotum and perineum (fournier gangrene). 61
33102002 2020
16
Xanthogranulomatous pyelonephritis diagnosed in an austere environment. 61
33102070 2020
17
Xanthogranulomatous pyelonephritis caused by fusobacterium nucleatum. Case report and review of literature. 61
33101996 2020
18
Pleural empyema secondary to xanthogranulomatous pyelonephritis. 61
33115938 2020
19
Minimally invasive nephrectomy for inflammatory renal disease. 61
32995279 2020
20
Xanthogranulomatous pyelonephritis: a comparison of open and minimally-invasive surgical approaches. 61
33000399 2020
21
Xanthogranulomatous Pyelonephritis With Direct Extension Into the Liver. 61
31991112 2020
22
Imaging of Renal Infections and Inflammatory Disease. 61
32792123 2020
23
[Xanthogranulomatous Pyelonephritis after Partial Nephrectomy Mimicking the Local Recurrence of Papillary Renal Cell Carcinoma]. 61
32988165 2020
24
The use of nephrostomy tubes in optimizing surgical conditions for a patient with xanthogranulomatous pyelonephritis. 61
32861264 2020
25
Xanthogranulomatous Ureteritis Mimicking Ureteral Involvement by Cancer in a Radical Cystectomy Specimen. 61
32493143 2020
26
Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review. 61
32493295 2020
27
Focal Xanthogranulomatous Pyelonephritis in Brachydactyly Mental Retardation Syndrome (2q37 Deletion Syndrome). 61
32341815 2020
28
A Rare Case of Pyonephrosis in an Infant Induced by Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae. 61
32587499 2020
29
Ureaplasma urealyticum infection presenting as pyelonephritis and perinephric abscess in an immunocompromised patient. 61
32414777 2020
30
Case report: Xanthogranulomatous pyelonephritis masquerading as cystic renal cell carcinoma. 61
31976820 2020
31
Native valve infective endocarditis due to ampicillin-resistant Escherichia coli in the postoperative period of a right radical nephrectomy due to xanthogranulomatous pyelonephritis. 61
31757432 2020
32
Ultrastructural evidence of the evolutional process in malakoplakia. 61
31298302 2020
33
Non-invasive papillary urothelial carcinoma, low-grade of the renal pelvis mimicking a xanthogranulomatous pyelonephritis in a male patient: A case report and review of literature. 61
32490707 2020
34
Xanthogranulomatous pyelonephritis due to calculi in a 5-year-old girl. 61
32779427 2020
35
Renal actinomycosis presenting as uro-cutaneous fistula. 61
31709154 2020
36
Imaging Manifestations of Acute and Chronic Renal Infection That Mimics Malignancy: How to Make the Diagnosis Using Computed Tomography and Magnetic Resonance Imaging. 61
31537315 2019
37
Xanthogranulomatous pyelonephritis. 61
31739986 2019
38
Xanthogranulomatous pyelonephritis with associated renal cell carcinoma. 61
31586963 2019
39
Xanthogranulomatous Pyelonephritis Causing Renocolic Fistula Presenting as Symptomatic Anemia. 61
31453021 2019
40
Bear paw sign: classic presentation of xanthogranulomatous pyelonephritis. 61
30597105 2019
41
Xanthogranulomatous Pyelonephritis: "Bear's Paw Sign". 61
31139769 2019
42
Gas in the kidney in asymptomatic Escherichia coli urinary tract infections in a patient with severe vesicoureteral reflex. 61
31249237 2019
43
Postpartum xanthogranulomatous pyelonephritis: A case report. 61
31032181 2019
44
[Xanthogranulomatous pyelonephritis]. 61
31626493 2019
45
Symmetric nephromegaly. 61
30178235 2019
46
Clinicopathological Spectrum of Xanthogranulomatous Pyelonephritis. 61
30983751 2019
47
Laparoscopic nephrectomy in xanthogranulomatous pyelonephritis. 61
31720037 2019
48
Effect of Kidney Volume on the Results of Nephrectomy Performed for Xanthogranulomatous Pyelonephritis. 61
30967976 2019
49
Surgical treatment of kidney tumor on a patient with second case of staghorn calculus and associated renal hydronephrosis: case report. 61
31380503 2019
50
Xanthogranulomatous Pyelonephritis: Synchronous Upper and Lower Gastrointestinal Bleed. 61
31043090 2019

Variations for Xanthogranulomatous Pyelonephritis

Expression for Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for Xanthogranulomatous Pyelonephritis

Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.66 SERPINA3 CRP CCL2
2 11.12 EGF CCL2
3 11.02 TFE3 EGF
4 10.23 SERPINA3 CCL2
5 9.83 CD68 CCL2

GO Terms for Xanthogranulomatous Pyelonephritis

Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.33 SERPINA3 CRP CCL2
2 humoral immune response GO:0006959 8.96 TFE3 CCL2
3 acute-phase response GO:0006953 8.62 SERPINA3 CRP

Sources for Xanthogranulomatous Pyelonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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