MCID: XNT001
MIFTS: 31

Xanthogranulomatous Pyelonephritis

Categories: Nephrological diseases

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

MalaCards integrated aliases for Xanthogranulomatous Pyelonephritis:

Name: Xanthogranulomatous Pyelonephritis 12 15
Pyelonephritis, Xanthogranulomatous 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11401
MeSH 44 D011705
NCIt 50 C123038
SNOMED-CT 68 197777006 38898003
UMLS 73 C0034188

Summaries for Xanthogranulomatous Pyelonephritis

MalaCards based summary : Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to renal tuberculosis and autosomal dominant polycystic kidney disease. An important gene associated with Xanthogranulomatous Pyelonephritis is NEXMIF (Neurite Extension And Migration Factor), and among its related pathways/superpathways are Immune response_Oncostatin M signaling via JAK-Stat in human cells and LDL Oxidation in Atherogenesis. Affiliated tissues include kidney, lung and liver, and related phenotype is immune system.

Related Diseases for Xanthogranulomatous Pyelonephritis

Diseases related to Xanthogranulomatous Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
# Related Disease Score Top Affiliating Genes
1 renal tuberculosis 30.8 LYZ NCF4 PKDREJ
2 autosomal dominant polycystic kidney disease 30.4 CCL2 EGF PKDREJ
3 pyelonephritis 11.2
4 endometrial adenosquamous carcinoma 10.9 EGF SERPINA3
5 heel spur 10.8 CRP HCCS
6 ovarian squamous cell carcinoma 10.8 CRP SMUG1
7 pyuria 10.7 CRP NUMA1
8 tricuspid valve prolapse 10.7 EGF PKDREJ
9 aortitis 10.7 CRP SMUG1
10 erdheim-chester disease 10.7 CCL2 SERPINA3
11 acute maxillary sinusitis 10.7 CRP HCCS
12 blue toe syndrome 10.6 CRP LYZ
13 breast lymphoma 10.6 ALK SMUG1
14 dermis tumor 10.6 LYZ SERPINA3
15 urinary tract obstruction 10.6 CCL2 EGF PKDREJ
16 cartilage disease 10.5 CRP SMUG1
17 pulmonary aspergilloma 10.5 CRP NUMA1 SMUG1
18 verruciform xanthoma of skin 10.5 CCL2 CD68
19 meningitis 10.4 CCL2 CRP LYZ
20 laryngeal tuberculosis 10.4 LYZ SMUG1
21 nodular tenosynovitis 10.4 CD68 SERPINA3
22 renal cell carcinoma, nonpapillary 10.4
23 endocervicitis 10.4 CCL2 CD68
24 retinal hemangioblastoma 10.4 LYZ PKDREJ SERPINA3
25 cutaneous solitary mastocytoma 10.4 LYZ SERPINA3
26 lemierre's syndrome 10.4 ALK CRP SMUG1
27 cell type cancer 10.4 ALK EGF SMUG1
28 acute proliferative glomerulonephritis 10.4 CCL2 LYZ
29 chronic pyelonephritis 10.3 CPN1 NEXMIF PKDREJ
30 adult lymphoma 10.3 ALK SMUG1
31 inflammatory mfh 10.3 CD68 SERPINA3
32 pulmonary artery leiomyosarcoma 10.3 CD68 SMUG1
33 sternum cancer 10.3 CD68 SMUG1
34 temporal arteritis 10.3 CCL2 CRP SERPINA3 SMUG1
35 central nervous system sarcoma 10.3 CD68 LYZ
36 pulmonary disease, chronic obstructive 10.3 CCL2 CRP SERPINA3
37 brain sarcoma 10.3 CD68 SMUG1
38 lipomatosis 10.3
39 amyloidosis 10.3
40 malignant giant cell tumor of soft parts 10.3 CD68 LYZ
41 in situ pulmonary adenocarcinoma 10.2 ALK LYZ SMUG1
42 melanotic neurilemmoma 10.2 CD68 LYZ
43 adult xanthogranuloma 10.2 CD68 LYZ
44 hepatitis 10.2
45 malakoplakia 10.2
46 pericoronitis 10.2 CD68 CRP
47 mesenteric lymphadenitis 10.2 CD68 CRP EGF
48 lactocele 10.2 CD68 SMUG1
49 perinephritis 10.2
50 hodgkin's lymphoma, lymphocytic depletion 10.1 ALK CD68

Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to Xanthogranulomatous Pyelonephritis

Symptoms & Phenotypes for Xanthogranulomatous Pyelonephritis

MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.32 CCL2 CD68 CPN1 CRP EGF ITGAX

Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

Search Clinical Trials , NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Cochrane evidence based reviews: pyelonephritis, xanthogranulomatous

Genetic Tests for Xanthogranulomatous Pyelonephritis

Anatomical Context for Xanthogranulomatous Pyelonephritis

MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

41
Kidney, Lung, Liver, Colon, Monocytes, Pancreas, Bone

Publications for Xanthogranulomatous Pyelonephritis

Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50) (show all 479)
# Title Authors Year
1
Laparoscopic Heminephrectomy of Chronically Obstructed Horseshoe Kidney Moiety with Staghorn Calculus, Massive Pyonephrosis, and Xanthogranulomatous Pyelonephritis. ( 29662958 )
2018
2
Xanthogranulomatous pyelonephritis complicating crizotinib treatment of an ALK-rearranged non-small-cell lung cancer. ( 29472032 )
2018
3
Extensive renal sinus lipomatosis in xanthogranulomatous pyelonephritis simulating liposarcoma. ( 29522292 )
2018
4
Delayed diagnosis of xanthogranulomatous pyelonephritis in a quadriplegic patient with uncontrolled cutaneous fistula: A case report. ( 29480882 )
2018
5
Xanthogranulomatous Pyelonephritis. ( 29514028 )
2018
6
Pyeloduodenal fistula complicating xanthogranulomatous pyelonephritis. ( 29785659 )
2018
7
Xanthogranulomatous pyelonephritis: A case report. ( 29888197 )
2018
8
Nephron-sparing management of Xanthogranulomatous pyelonephritis presenting as spontaneous renal hemorrhage: a case report and literature review. ( 29866085 )
2018
9
Focal Xanthogranulomatous Pyelonephritis with Pulmonary Lesions on the Background of Type Two Diabetes Mellitus. ( 29666742 )
2018
10
Characterization of the Macrophage Infiltrate in a Case of Xanthogranulomatous Pyelonephritis. ( 29770220 )
2018
11
Xanthogranulomatous Pyelonephritis: A Complicated Febrile Urinary Tract Infection Detected by Point-of-Care Ultrasound in the Emergency Department. ( 29753570 )
2018
12
Xanthogranulomatous pyelonephritis: a case with rare adhesion to pancreas. ( 29177841 )
2017
13
A Case of Xanthogranulomatous Pyelonephritis Associated with Renoduodenal Fistula. ( 28424736 )
2017
14
Xanthogranulomatous pyelonephritis presenting as acute pleuritic chest pain: a case report. ( 28399929 )
2017
15
Spontaneous Nephrocutaneous Fistula: Rare Complication of Xanthogranulomatous Pyelonephritis. ( 28138432 )
2017
16
High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. ( 28491170 )
2017
17
Xanthogranulomatous pyelonephritis in a paediatric cohort (1963-2016): Outcomes from a large single-center series. ( 29233628 )
2017
18
Xanthogranulomatous pyelonephritis with reno-colic fistula: A rare complication of urinary tract infection. ( 29527279 )
2017
19
Massive Renal Replacement Lipomatosis With Foci of Xanthogranulomatous Pyelonephritis in a Horseshoe Kidney. ( 28443241 )
2017
20
Xanthogranulomatous Pyelonephritis Manifesting as a Nephrocutaneous Fistula in a 5-Year-Old Female. ( 28131924 )
2017
21
Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter. ( 29075296 )
2017
22
Acute leukemia masquerading as xanthogranulomatous pyelonephritis. ( 28479773 )
2017
23
Early Progression of Xanthogranulomatous Pyelonephritis in Children Might Be Dependent on Vimentin Expression. ( 28978905 )
2017
24
Xanthogranulomatous pyelonephritis presenting as a type IV renal cyst. ( 28522934 )
2017
25
Xanthogranulomatous Pyelonephritis. ( 27556196 )
2016
26
A 13-Month-Old With Xanthogranulomatous Pyelonephritis With Features of Renal Malakoplakia. ( 26894199 )
2016
27
Septic lung metastasis in xanthogranulomatous pyelonephritis. ( 27578950 )
2016
28
Renal squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: Case report and review of literature. ( 27257454 )
2016
29
Xanthogranulomatous pyelonephritis presenting as Proteus preperitoneal abscess. ( 27915241 )
2016
30
Combination of Surgical Drainage and Renal Artery Embolization: An Alternative Treatment for Xanthogranulomatous Pyelonephritis. ( 28028578 )
2016
31
Co-existing malakoplakia and xanthogranulomatous pyelonephritis of kidney: Two different spectrum of same disease process. ( 27141206 )
2016
32
Xanthogranulomatous pyelonephritis. ( 27307431 )
2016
33
An unusual presentation of xanthogranulomatous pyelonephritis: psoas abscess with reno-colic fistula. ( 27471599 )
2016
34
Xanthogranulomatous Pyelonephritis. ( 27743436 )
2016
35
Renal Sarcoidosis Mimicking Xanthogranulomatous Pyelonephritis. ( 27590254 )
2016
36
Xanthogranulomatous pyelonephritis presenting as a pseudotumour. ( 26858786 )
2016
37
Xanthogranulomatous pyelonephritis and renal tubulopapillary adenomas: A rare coexistence. ( 27721288 )
2016
38
Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report. ( 26998145 )
2016
39
Xanthogranulomatous Pyelonephritis of a Lower Pole Moiety in a Duplicated Collecting System Kidney. ( 26435873 )
2015
40
Bilateral xanthogranulomatous pyelonephritis: Morphologically rotund, functionally lame! ( 26199481 )
2015
41
Xanthogranulomatous Pyelonephritis Associated with Hepatic Dysfunction in Pregnancy. ( 26078894 )
2015
42
Xanthogranulomatous pyelonephritis with colesional actinomycosis in a 63-year-old man. ( 25878419 )
2015
43
A case report of a xanthogranulomatous pyelonephritis case mimicking the recurrence of renal cell carcinoma after partial nephrectomy. ( 26692680 )
2015
44
Bear's Paw Sign: A Classic Presentation of Xanthogranulomatous Pyelonephritis. ( 26168999 )
2015
45
Xanthogranulomatous Pyelonephritis with Staghorn Calculus, Acute Gangrenous Appendicitis and Enterocolitis: A Multidisciplinary Challenge of Kidney-Preserving Conservative Therapy. ( 26889137 )
2015
46
Nephrobronchial fistula and lung abscess secondary to Xanthogranulomatous pyelonephritis. ( 26180394 )
2015
47
A case of xanthogranulomatous pyelonephritis mimicking Wilms tumor. ( 27186708 )
2015
48
Rare Co-existence of Squamous Cell Carcinoma with Infiltration of Renal Vein and Xanthogranulomatous Pyelonephritis. ( 26816904 )
2015
49
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. ( 26490542 )
2015
50
Xanthogranulomatous pyelonephritis: critical analysis of 18 cases from a rural tertiary care centre of India. ( 25935947 )
2014

Variations for Xanthogranulomatous Pyelonephritis

Expression for Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for Xanthogranulomatous Pyelonephritis

Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.23 CCL2 SERPINA3
2 9.83 CCL2 CD68

GO Terms for Xanthogranulomatous Pyelonephritis

Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 8.8 CCL2 HCCS ITGAX

Sources for Xanthogranulomatous Pyelonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
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45 MESH via Orphanet
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49 NCI
50 NCIt
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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