MCID: XNT001
MIFTS: 32

Xanthogranulomatous Pyelonephritis

Categories: Nephrological diseases

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

MalaCards integrated aliases for Xanthogranulomatous Pyelonephritis:

Name: Xanthogranulomatous Pyelonephritis 12 15
Pyelonephritis, Xanthogranulomatous 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11401
MeSH 44 D011705
NCIt 50 C123038
SNOMED-CT 68 38898003
UMLS 73 C0034188

Summaries for Xanthogranulomatous Pyelonephritis

MalaCards based summary : Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to renal tuberculosis and renal cell carcinoma, papillary, 1. An important gene associated with Xanthogranulomatous Pyelonephritis is NEXMIF (Neurite Extension And Migration Factor), and among its related pathways/superpathways are ErbB signaling pathway and Immune response_Oncostatin M signaling via JAK-Stat in human cells. Affiliated tissues include kidney, lung and liver, and related phenotype is immune system.

Related Diseases for Xanthogranulomatous Pyelonephritis

Diseases related to Xanthogranulomatous Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 renal tuberculosis 30.6 CRP LYZ NCF4
2 renal cell carcinoma, papillary, 1 29.7 FH PRCC TFE3
3 pyelonephritis 11.3
4 renal cell carcinoma, nonpapillary 10.5
5 lipomatosis 10.4
6 amyloidosis 10.4
7 malakoplakia 10.4
8 squamous cell carcinoma 10.3
9 endometrial adenosquamous carcinoma 10.3 EGF SERPINA3
10 horseshoe kidney 10.3
11 japanese spotted fever 10.3 CCL2 CRP
12 erdheim-chester disease 10.3 CCL2 SERPINA3
13 heel spur 10.2 CRP HCCS
14 pyuria 10.2 CRP NUMA1
15 acute maxillary sinusitis 10.2 CRP HCCS
16 gastrointestinal tuberculosis 10.2 CRP SMUG1
17 aortitis 10.2 CRP SMUG1
18 breast cyst 10.2 EGF SERPINA3
19 cystitis 10.2 CCL2 CRP EGF
20 dermis tumor 10.2 LYZ SERPINA3
21 adenocarcinoma 10.2
22 transitional cell carcinoma 10.2
23 acute cystitis 10.2
24 nephrolithiasis 10.2
25 chlamydia pneumonia 10.2 CPN1 CRP
26 blue toe syndrome 10.2 CRP LYZ
27 cartilage disease 10.2 CRP SMUG1
28 acute proliferative glomerulonephritis 10.2 CCL2 LYZ
29 cutaneous solitary mastocytoma 10.2 LYZ SERPINA3
30 chronic pyelonephritis 10.2 CPN1 NEXMIF
31 nodular tenosynovitis 10.2 CD68 SERPINA3
32 endocervicitis 10.2 CCL2 CD68
33 central nervous system vasculitis 10.2 CRP SMUG1
34 inflammatory mfh 10.2 CD68 SERPINA3
35 tuberculous peritonitis 10.2 CRP SMUG1
36 ischemic heart disease 10.2 CCL2 CRP
37 pericoronitis 10.1 CD68 CRP
38 pulmonary disease, chronic obstructive 10.1 CCL2 CRP SERPINA3
39 scrotal carcinoma 10.1 CD68 SERPINA3
40 respiratory system disease 10.1 CCL2 CRP SMUG1
41 pulmonary artery leiomyosarcoma 10.1 CD68 SMUG1
42 meningitis 10.1 CCL2 CRP LYZ
43 sternum cancer 10.1 CD68 SMUG1
44 urinary system disease 10.1 CCL2 CRP LYZ
45 laryngeal tuberculosis 10.1 LYZ SMUG1
46 brain sarcoma 10.1 CD68 SMUG1
47 pulmonary aspergilloma 10.1 CRP NUMA1 SMUG1
48 central nervous system sarcoma 10.1 CD68 LYZ
49 nervous system disease 10.1 CCL2 CRP SMUG1
50 cardiomyopathy, infantile histiocytoid 10.1 CD68 LYZ

Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to Xanthogranulomatous Pyelonephritis

Symptoms & Phenotypes for Xanthogranulomatous Pyelonephritis

MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.32 CCL2 CD68 CPN1 CRP EGF ITGAX

Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

Search Clinical Trials , NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Cochrane evidence based reviews: pyelonephritis, xanthogranulomatous

Genetic Tests for Xanthogranulomatous Pyelonephritis

Anatomical Context for Xanthogranulomatous Pyelonephritis

MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

41
Kidney, Lung, Liver, Bone, Spinal Cord, Skin, Brain

Publications for Xanthogranulomatous Pyelonephritis

Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50) (show all 501)
# Title Authors Year
1
Laparoscopic Heminephrectomy of Chronically Obstructed Horseshoe Kidney Moiety with Staghorn Calculus, Massive Pyonephrosis, and Xanthogranulomatous Pyelonephritis. ( 29662958 )
2018
2
Xanthogranulomatous pyelonephritis complicating crizotinib treatment of an ALK-rearranged non-small-cell lung cancer. ( 29472032 )
2018
3
Extensive renal sinus lipomatosis in xanthogranulomatous pyelonephritis simulating liposarcoma. ( 29522292 )
2018
4
Delayed diagnosis of xanthogranulomatous pyelonephritis in a quadriplegic patient with uncontrolled cutaneous fistula: A case report. ( 29480882 )
2018
5
Xanthogranulomatous Pyelonephritis. ( 29514028 )
2018
6
Pyeloduodenal fistula complicating xanthogranulomatous pyelonephritis. ( 29785659 )
2018
7
Xanthogranulomatous pyelonephritis: A case report. ( 29888197 )
2018
8
Nephron-sparing management of Xanthogranulomatous pyelonephritis presenting as spontaneous renal hemorrhage: a case report and literature review. ( 29866085 )
2018
9
Focal Xanthogranulomatous Pyelonephritis with Pulmonary Lesions on the Background of Type Two Diabetes Mellitus. ( 29666742 )
2018
10
Characterization of the Macrophage Infiltrate in a Case of Xanthogranulomatous Pyelonephritis. ( 29770220 )
2018
11
Xanthogranulomatous Pyelonephritis: A Complicated Febrile Urinary Tract Infection Detected by Point-of-Care Ultrasound in the Emergency Department. ( 29753570 )
2018
12
Xanthogranulomatous pyelonephritis with psoas abscess and renocolic fistula. ( 29988681 )
2018
13
Pyeloduodenal Fistula in Xanthogranulomatous Pyelonephritis: A Series of Two Cases. ( 30005725 )
2018
14
Laparoscopic Nephrectomy for the Management of Xanthogranulomatous Pyelonephritis: Still a Challenging Procedure. ( 30024301 )
2018
15
Urinothorax Caused by Xanthogranulomatous Pyelonephritis. ( 30079257 )
2018
16
Bear paw sign: Xanthogranulomatous pyelonephritis. ( 30309087 )
2018
17
Xanthogranulomatous pyelonephritis presenting as a left-sided pleural effusion. ( 30377531 )
2018
18
Xanthogranulomatous pyelonephritis in adults: clinical, biological, radiological and therapeutic main findings in diffuse and focal forms. About 42 cases. ( 30430527 )
2018
19
Xanthogranulomatous pyelonephritis: a case with rare adhesion to pancreas. ( 29177841 )
2017
20
A Case of Xanthogranulomatous Pyelonephritis Associated with Renoduodenal Fistula. ( 28424736 )
2017
21
Xanthogranulomatous pyelonephritis presenting as acute pleuritic chest pain: a case report. ( 28399929 )
2017
22
Spontaneous Nephrocutaneous Fistula: Rare Complication of Xanthogranulomatous Pyelonephritis. ( 28138432 )
2017
23
High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. ( 28491170 )
2017
24
Xanthogranulomatous pyelonephritis in a paediatric cohort (1963-2016): Outcomes from a large single-center series. ( 29233628 )
2017
25
Xanthogranulomatous pyelonephritis with reno-colic fistula: A rare complication of urinary tract infection. ( 29527279 )
2017
26
Massive Renal Replacement Lipomatosis With Foci of Xanthogranulomatous Pyelonephritis in a Horseshoe Kidney. ( 28443241 )
2017
27
Xanthogranulomatous Pyelonephritis Manifesting as a Nephrocutaneous Fistula in a 5-Year-Old Female. ( 28131924 )
2017
28
Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter. ( 29075296 )
2017
29
Acute leukemia masquerading as xanthogranulomatous pyelonephritis. ( 28479773 )
2017
30
Early Progression of Xanthogranulomatous Pyelonephritis in Children Might Be Dependent on Vimentin Expression. ( 28978905 )
2017
31
Xanthogranulomatous pyelonephritis presenting as a type IV renal cyst. ( 28522934 )
2017
32
Xanthogranulomatous Pyelonephritis. ( 27556196 )
2016
33
A 13-Month-Old With Xanthogranulomatous Pyelonephritis With Features of Renal Malakoplakia. ( 26894199 )
2016
34
Septic lung metastasis in xanthogranulomatous pyelonephritis. ( 27578950 )
2016
35
Renal squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: Case report and review of literature. ( 27257454 )
2016
36
Xanthogranulomatous pyelonephritis presenting as Proteus preperitoneal abscess. ( 27915241 )
2016
37
Combination of Surgical Drainage and Renal Artery Embolization: An Alternative Treatment for Xanthogranulomatous Pyelonephritis. ( 28028578 )
2016
38
Co-existing malakoplakia and xanthogranulomatous pyelonephritis of kidney: Two different spectrum of same disease process. ( 27141206 )
2016
39
Xanthogranulomatous pyelonephritis. ( 27307431 )
2016
40
An unusual presentation of xanthogranulomatous pyelonephritis: psoas abscess with reno-colic fistula. ( 27471599 )
2016
41
Xanthogranulomatous Pyelonephritis. ( 27743436 )
2016
42
Renal Sarcoidosis Mimicking Xanthogranulomatous Pyelonephritis. ( 27590254 )
2016
43
Xanthogranulomatous pyelonephritis presenting as a pseudotumour. ( 26858786 )
2016
44
Xanthogranulomatous pyelonephritis and renal tubulopapillary adenomas: A rare coexistence. ( 27721288 )
2016
45
Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report. ( 26998145 )
2016
46
Xanthogranulomatous Pyelonephritis of a Lower Pole Moiety in a Duplicated Collecting System Kidney. ( 26435873 )
2015
47
Bilateral xanthogranulomatous pyelonephritis: Morphologically rotund, functionally lame! ( 26199481 )
2015
48
Xanthogranulomatous Pyelonephritis Associated with Hepatic Dysfunction in Pregnancy. ( 26078894 )
2015
49
Xanthogranulomatous pyelonephritis with colesional actinomycosis in a 63-year-old man. ( 25878419 )
2015
50
A case report of a xanthogranulomatous pyelonephritis case mimicking the recurrence of renal cell carcinoma after partial nephrectomy. ( 26692680 )
2015

Variations for Xanthogranulomatous Pyelonephritis

Expression for Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for Xanthogranulomatous Pyelonephritis

Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.37 EGF FH PRCC TFE3
2 10.43 CCL2 SERPINA3
3 10.16 CCL2 CD68

GO Terms for Xanthogranulomatous Pyelonephritis

Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.26 CCL2 CRP LYZ SERPINA3
2 animal organ morphogenesis GO:0009887 8.8 CCL2 HCCS ITGAX

Sources for Xanthogranulomatous Pyelonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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