YF
MCID: YLL002
MIFTS: 65

Yellow Fever (YF)

Categories: Infectious diseases, Liver diseases, Rare diseases, Skin diseases

Aliases & Classifications for Yellow Fever

MalaCards integrated aliases for Yellow Fever:

Name: Yellow Fever 12 76 53 59 55 3 44 15 73
Jungle Yellow Fever 12 73
Urban Yellow Fever 12 73
Yf 53 59
Sylvatic Yellow Fever 12
Yellow Fever, Sylvan 12
Bronze John 59
Yellow Jack 59

Characteristics:

Orphanet epidemiological data:

59
yellow fever
Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 59  
Rare infectious diseases


Summaries for Yellow Fever

CDC : 3 The yellow fever virus is found in tropical and subtropical areas of Africa and South America. The virus is spread to people by the bite of an infected mosquito. Yellow fever is a very rare cause of illness in U.S. travelers. Illness ranges from a fever with aches and pains to severe liver disease with bleeding and yellowing skin (jaundice). Yellow fever infection is diagnosed based on laboratory testing, a person’s symptoms, and travel history. There is no medicine to treat or cure infection. To prevent getting sick from yellow fever, use insect repellent, wear long-sleeved shirts and long pants, and get vaccinated.

MalaCards based summary : Yellow Fever, also known as jungle yellow fever, is related to west nile virus and encephalitis. An important gene associated with Yellow Fever is EIF2AK4 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Vaccines and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and testes, and related phenotypes are nausea and vomiting and hypothermia

Disease Ontology : 12 A viral infectious disease that results in infection, has material basis in Yellow fever virus, which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.

Wikipedia : 76 Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever,... more...

Related Diseases for Yellow Fever

Diseases related to Yellow Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 207)
# Related Disease Score Top Affiliating Genes
1 west nile virus 32.2 CCR5 OAS1 RSAD2
2 encephalitis 30.8 CCL2 CCL5 CCR5 RSAD2
3 chikungunya 30.5 CCL2 CCL5 IL6 RSAD2
4 egg allergy 30.4 IL4 IL5
5 measles 30.3 IFNB1 IL4 IL6
6 viral encephalitis 30.1 CCL2 CCL5 IL6
7 human immunodeficiency virus infectious disease 29.9 CCL5 CCR5 IL6 TLR9
8 cytomegalovirus infection 29.8 CCL2 CCL5 IL6
9 meningoencephalitis 29.8 CCL5 IL6 TLR9
10 dermatitis 29.7 IL4 IL5 TLR9
11 influenza 29.7 CCL5 IFNB1 IRF7 RSAD2 TLR9
12 meningitis 29.7 CCL2 IL6 TLR9
13 malaria 29.7 CCL2 CCL5 IL4 IL5 IL6 TLR9
14 viral infectious disease 29.6 CCL5 CCR5 IFNB1 IL4 IL6 IRF7
15 colitis 29.5 IL4 IL6 TLR9
16 dermatitis, atopic 29.3 CCL2 CCL5 IL4 IL5 TLR9
17 autoimmune disease 29.3 CCL2 IL4 IL5 IL6 TLR9
18 multiple sclerosis 28.9 CCL2 CCL5 CCR5 IFNB1 IL4 IL5
19 hemorrhagic fever 11.3
20 kyasanur forest disease 10.9
21 hepatitis 10.3
22 japanese encephalitis 10.3
23 dengue virus 10.3
24 whiplash 10.2 CCL5 CCR5
25 scorpion envenomation 10.2 CCL5 IL6
26 obesity-hypoventilation syndrome 10.2 CCL5 IL6
27 angioimmunoblastic lymphadenopathy with dysproteinemia 10.2 IL5 IL6
28 bagassosis 10.2 IL5 IL6
29 st. louis encephalitis 10.2
30 typhoid fever 10.2
31 hepatitis a 10.2
32 smallpox 10.2
33 diabetic foot ulcers 10.1 CCL2 IL6
34 nickel allergic contact dermatitis 10.1 IL4 IL5
35 cough variant asthma 10.1 IL4 IL5
36 denture stomatitis 10.1 CCL2 IL6
37 sulfamethoxazole allergy 10.1 IL4 IL5
38 chronic eosinophilic pneumonia 10.1 CCL2 CCL5 IL5
39 atopic keratoconjunctivitis 10.1 IL4 IL5
40 b-cell growth factor 10.1 IL4 IL6
41 west nile encephalitis 10.1 OAS1 TLR9
42 gaucher disease, type ii 10.1 IL4 IL5
43 chronic nk-cell lymphocytosis 10.1 CCL5 CCR5
44 pulmonary sarcoidosis 10.1 CCL2 CCL5 CCR5
45 angiostrongyliasis 10.1 IL4 IL5
46 orofacial granulomatosis 10.1 CCL5 CCR5 IL4
47 ocular toxoplasmosis 10.1 CCR5 TLR9
48 papillary conjunctivitis 10.1 IL4 IL6
49 chronic conjunctivitis 10.1 CCL5 IL4 IL5
50 intrinsic asthma 10.1 IL4 IL5

Graphical network of the top 20 diseases related to Yellow Fever:



Diseases related to Yellow Fever

Symptoms & Phenotypes for Yellow Fever

Human phenotypes related to Yellow Fever:

59 32 (show all 29)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 nausea and vomiting 59 32 frequent (33%) Frequent (79-30%) HP:0002017
2 hypothermia 59 32 occasional (7.5%) Occasional (29-5%) HP:0002045
3 encephalitis 59 32 occasional (7.5%) Occasional (29-5%) HP:0002383
4 hypotension 59 32 occasional (7.5%) Occasional (29-5%) HP:0002615
5 renal insufficiency 59 32 occasional (7.5%) Occasional (29-5%) HP:0000083
6 proteinuria 59 32 frequent (33%) Frequent (79-30%) HP:0000093
7 nephropathy 59 32 occasional (7.5%) Occasional (29-5%) HP:0000112
8 photophobia 59 32 occasional (7.5%) Occasional (29-5%) HP:0000613
9 dehydration 59 32 occasional (7.5%) Occasional (29-5%) HP:0001944
10 fever 59 32 hallmark (90%) Very frequent (99-80%) HP:0001945
11 arthralgia 59 32 frequent (33%) Frequent (79-30%) HP:0002829
12 arrhythmia 59 32 occasional (7.5%) Occasional (29-5%) HP:0011675
13 abdominal pain 59 32 frequent (33%) Frequent (79-30%) HP:0002027
14 congestive heart failure 59 32 occasional (7.5%) Occasional (29-5%) HP:0001635
15 jaundice 59 32 frequent (33%) Frequent (79-30%) HP:0000952
16 anorexia 59 32 frequent (33%) Frequent (79-30%) HP:0002039
17 myalgia 59 32 frequent (33%) Frequent (79-30%) HP:0003326
18 malignant hyperthermia 59 32 occasional (7.5%) Occasional (29-5%) HP:0002047
19 gastrointestinal hemorrhage 59 32 frequent (33%) Frequent (79-30%) HP:0002239
20 chest pain 59 32 frequent (33%) Frequent (79-30%) HP:0100749
21 diarrhea 59 32 frequent (33%) Frequent (79-30%) HP:0002014
22 meningitis 59 32 occasional (7.5%) Occasional (29-5%) HP:0001287
23 acute hepatic failure 59 32 occasional (7.5%) Occasional (29-5%) HP:0006554
24 lethargy 59 32 occasional (7.5%) Occasional (29-5%) HP:0001254
25 headache 59 32 hallmark (90%) Very frequent (99-80%) HP:0002315
26 spontaneous abortion 59 32 frequent (33%) Frequent (79-30%) HP:0005268
27 oliguria 59 32 frequent (33%) Frequent (79-30%) HP:0100520
28 menometrorrhagia 59 32 frequent (33%) Frequent (79-30%) HP:0400008
29 cardiorespiratory arrest 59 32 occasional (7.5%) Occasional (29-5%) HP:0006543

MGI Mouse Phenotypes related to Yellow Fever:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 CCL5 CCR5 EIF2AK4 IFNB1 IL4 IL5
2 homeostasis/metabolism MP:0005376 9.9 CCR5 EIF2AK4 IFNB1 IL4 IL5 IL6
3 immune system MP:0005387 9.77 CCL2 CCL5 CCR5 EIF2AK4 IFNB1 IL4
4 liver/biliary system MP:0005370 9.17 CCR5 EIF2AK4 IL4 IL5 IL6 SCP2

Drugs & Therapeutics for Yellow Fever

Drugs for Yellow Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
2 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
3
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
4
Lactitol Investigational Phase 3 585-86-4 3871
5 Heptavalent Pneumococcal Conjugate Vaccine Phase 3,Phase 2
6 Retinol palmitate Phase 3
7 Antioxidants Phase 3
8 Micronutrients Phase 3
9 Protective Agents Phase 3
10 retinol Phase 3
11 Trace Elements Phase 3
12 Vitamins Phase 3
13
Benzocaine Approved, Investigational Phase 1, Phase 2 94-09-7, 1994-09-7 2337
14 tannic acid Approved Phase 1, Phase 2
15 Immunoglobulins Phase 2,Phase 1,Not Applicable
16 Antibodies Phase 2,Phase 1,Not Applicable
17 Antimetabolites Phase 2
18 Hypolipidemic Agents Phase 2
19 Anti-Inflammatory Agents Phase 2
20 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
21 Anticholesteremic Agents Phase 2
22 Lipid Regulating Agents Phase 2
23
Aluminum sulfate Approved Phase 1 10043-01-3
24
Mannitol Approved, Investigational Phase 1 69-65-8 453 6251
25
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
26 Immunoglobulins, Intravenous Phase 1
27 gamma-Globulins Phase 1
28 Rho(D) Immune Globulin Phase 1
29 Natriuretic Agents Phase 1
30 diuretics Phase 1
31
leucovorin Approved 58-05-9 6006 143
32
Methotrexate Approved 59-05-2, 1959-05-2 126941
33
Folic Acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
34 Folate
35 Vitamin B9
36 Vitamin B Complex
37 Immunosuppressive Agents
38 Antimetabolites, Antineoplastic
39 Antirheumatic Agents
40 Folic Acid Antagonists
41 Dermatologic Agents
42 Nucleic Acid Synthesis Inhibitors
43 Antibodies, Blocking

Interventional clinical trials:

(show top 50) (show all 54)
# Name Status NCT ID Phase Drugs
1 Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali Completed NCT02286895 Phase 4
2 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
3 Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals Recruiting NCT03132311 Phase 4
4 Immunogenicity of Co-administered Yellow Fever and Measles, Mumps, and Rubella (MMR) Vaccines Recruiting NCT03368495 Phase 4
5 Immunity Period After One Dose of Yellow Fever Vaccine in Adults and Children (Paraiba Study) Active, not recruiting NCT02555072 Phase 4
6 Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) Active, not recruiting NCT02991495 Phase 4
7 Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 Months Old Not yet recruiting NCT03725618 Phase 4
8 The Yellow Fever Vaccine Immunity in HIV Infected Patients : Development of New Assays for Virological and Immunological Monitoring in HIV Infected Patient. Completed NCT01426243 Phase 3
9 Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers Completed NCT01436396 Phase 3
10 A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults Completed NCT01466387 Phase 3
11 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
12 Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Administered With a Yellow Fever Vaccine in Adults Recruiting NCT03342898 Phase 3
13 Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. Active, not recruiting NCT02699099 Phase 3
14 Phase 3 Study of 10-valent Pneumococcal Conjugate Vaccine (PNEUMOSIL) in Healthy Infants Active, not recruiting NCT03197376 Phase 3
15 Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®) Completed NCT00982137 Phase 2
16 Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine Completed NCT01488890 Phase 2
17 The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans Completed NCT01943305 Phase 2
18 Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis Completed NCT00723489 Phase 1, Phase 2 YFV-17D Placebo
19 Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen Completed NCT00436007 Phase 2
20 Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years Completed NCT00788151 Phase 2
21 Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects Completed NCT00730288 Phase 2
22 Impact of GSK Biologicals' 2189242A Vaccine on Nasopharyngeal Carriage, Safety & Immunogenicity in Children & Infants Completed NCT01262872 Phase 2
23 Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South America Completed NCT01187433 Phase 2
24 Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin America Completed NCT00993447 Phase 2
25 Yellow Fever Vaccine on Statin/ Non Statin Subjects Recruiting NCT03116802 Phase 2 Stamaril (live attenuated yellow fever vaccine)
26 Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina Faso Recruiting NCT03614533 Phase 2
27 Trial of Yellow Fever Inactivated Vaccine Completed NCT00995865 Phase 1
28 Yellow Fever Virus Vaccine and Immune Globulin Study Completed NCT00254826 Phase 1
29 A Phase I Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers Completed NCT02743455 Phase 1 ISA-720
30 Phase I Study of West Nile Virus Vaccine Completed NCT00300417 Phase 1 VRC-WNVDNA020-00-VP
31 A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects. Completed NCT02963909 Phase 1
32 Safety and Tolerability of an Antibody Against Yellow Fever Virus (TY014) in Humans Recruiting NCT03776786 Phase 1
33 Yellow Fever Vaccination Under Low Dose Methotrexate Therapy Unknown status NCT02383680
34 Immunity After Two Doses of Yellow Fever Vaccine Completed NCT02572518
35 Clinical Study of Immunity Duration of Yellow Fever Vaccine in Military Completed NCT03338231
36 Characterization of T Cell Responses Following Yellow Fever Virus Vaccination in Healthy Adults Completed NCT00616356
37 Passive Enhanced Safety Surveillance of Stamaril® Vaccine in Korea Completed NCT03541694
38 Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines Completed NCT01765413 Not Applicable
39 The Effect of Extended Yellow Fever Vaccine Information on Symptom Reports Following Vaccination Completed NCT00708630 Not Applicable
40 Seroprevalence and Incidence of Lassa Fever in the Rural Commune of Sibirila, District of Bougouni, Mali Completed NCT02311387
41 Evaluation of the Safety & Performance of 2 Intradermal Safety Devices Completed NCT02556047 Not Applicable
42 Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children Completed NCT01391819 Not Applicable
43 The Interaction Between Measles and DTP Vaccination Completed NCT02710045 Not Applicable
44 Yellow Fever Vaccine in Patients With Rheumatic Diseases Recruiting NCT03430388 Not Applicable
45 Yellow Fever Immune Response at Single Cell Resolution Recruiting NCT03458780 Yellow Fever Vaccine
46 "Persistence of Neutralizing Antibodies Against Yellow Fever (YF) in HIV-infected Patients" Recruiting NCT03591003
47 Immune Responses to Yellow Fever Vaccine Recruiting NCT01244802
48 Cohort of Patients Infected by an Arbovirus Recruiting NCT01099852
49 Vaccines Immunogenicity in Renal, Hepatic, Cardiac or Pulmonary Transplanted Children Recruiting NCT03180359 Not Applicable
50 Turnover of Antigen Specific Lymphocytes After Immunization With the Yellow Fever Vaccine Active, not recruiting NCT01290055 Not Applicable

Search NIH Clinical Center for Yellow Fever

Cochrane evidence based reviews: yellow fever

Genetic Tests for Yellow Fever

Anatomical Context for Yellow Fever

MalaCards organs/tissues related to Yellow Fever:

41
Liver, Skin, Testes, T Cells, Eye, Kidney, Lung

Publications for Yellow Fever

Articles related to Yellow Fever:

(show top 50) (show all 1055)
# Title Authors Year
1
A qualitatively validated mathematical-computational model of the immune response to the yellow fever vaccine. ( 29801432 )
2018
2
Yellow Fever - What It Means for Singapore. ( 29911734 )
2018
3
Existing and potential infection risk zones of yellow fever worldwide: a modelling analysis. ( 29398634 )
2018
4
Metagenomic analysis reveals Hepatitis A virus in suspected yellow fever cases in Brazil. ( 29211109 )
2018
5
Evidence for Multiple Sylvatic Transmission Cycles During the 2016-2017 Yellow Fever Virus Outbreak, Brazil. ( 29427798 )
2018
6
Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. ( 29933925 )
2018
7
Modeling the elevated risk of yellow fever among travelers visiting Brazil, 2018. ( 29961429 )
2018
8
Notes from the Field: Errors in Administration of an Excess Dosage of Yellow Fever Vaccine - United States, 2017. ( 29370153 )
2018
9
Yellow fever vaccination coverage in French Guiana. ( 29303736 )
2018
10
What Does the Future Hold for Yellow Fever Virus? (I). ( 29890711 )
2018
11
The risk of urban yellow fever resurgence in Aedes-infested American cities. ( 29843824 )
2018
12
Zika, dengue and yellow fever viruses induce differential anti-viral immune responses in human monocytic and first trimester trophoblast cells. ( 29331320 )
2018
13
Gold nanoparticles coupled with graphene quantum dots in organized medium to quantify aminoglycoside anti-biotics in yellow fever vaccine after solid phase extraction using a selective imprinted polymer. ( 29960239 )
2018
14
Potential yellow fever epidemics in unexposed populations. ( 29875511 )
2018
15
Duration of post-vaccination immunity to yellow fever in volunteers eight years after a dose-response study. ( 29784469 )
2018
16
Yellow fever: a major threat to public health. ( 29407015 )
2018
17
Controversies over the scientific name of the principal mosquito vector of yellow fever virus - expediency versus validity. ( 29757506 )
2018
18
Phylogeny of Yellow Fever Virus, Uganda, 2016. ( 29798746 )
2018
19
Yellow Fever Vaccine for People Living With HIV Infection. ( 29217414 )
2018
20
Stepping up local efforts to stop global spread of yellow fever. ( 29904218 )
2018
21
Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204. ( 29387474 )
2018
22
Development of a non-destructive method for determining protein nitrogen in a yellow fever vaccine by near infrared spectroscopy and multivariate calibration. ( 29751350 )
2018
23
Identification of Dengue and Chikungunya Cases Among Suspected Cases of Yellow Fever in the Democratic Republic of the Congo. ( 29768102 )
2018
24
Places, attitudes and moments during the epidemics: representations of yellow fever and cholera in the city of Buenos Aires, 1867-1871. ( 29898124 )
2018
25
Development of multiplex real time reverse transcriptase PCR assay for simultaneous detection of Zika, Dengue, Yellow Fever and Chikungunya Viruses in a single tube. ( 29979812 )
2018
26
Plant-Produced Subunit Vaccine Candidates against Yellow Fever Induce Virus Neutralizing Antibodies and Confer Protection against Viral Challenge in Animal Models. ( 29231157 )
2018
27
Yellow fever in two unvaccinated French tourists to Brazil, January and March, 2018. ( 29845927 )
2018
28
Modelling the large-scale yellow fever outbreak in Luanda, Angola, and the impact of vaccination. ( 29338001 )
2018
29
Re-evaluate yellow fever risk in Asia-Pacific region. ( 29388975 )
2018
30
Ocular manifestations of emerging arboviruses: Dengue fever, Chikungunya, Zika virus, West Nile virus, and yellow fever. ( 29929827 )
2018
31
International travel between global urban centres vulnerable to yellow fever transmission. ( 29875519 )
2018
32
A natural agonist of mosquito TRPA1 from the medicinal plant Cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito Aedes aegypti. ( 29425195 )
2018
33
Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak - Preliminary Report. ( 29443626 )
2018
34
Persistence of Yellow fever virus outside the Amazon Basin, causing epidemics in Southeast Brazil, from 2016 to 2018. ( 29864115 )
2018
35
Ultrastructural Analysis of Chikungunya Virus Dissemination from the Midgut of the Yellow Fever Mosquito, Aedes aegypti. ( 30340365 )
2018
36
Molecular epidemiology of dengue, yellow fever, Zika and Chikungunya arboviruses: An update. ( 30444971 )
2018
37
Genetic variability of the Aedes aegypti (Diptera: Culicidae) mosquito in El Salvador, vector of dengue, yellow fever, chikungunya and Zika. ( 30547835 )
2018
38
Current status, challenges and perspectives in the development of vaccines against yellow fever, dengue, Zika and chikungunya viruses. ( 29551394 )
2018
39
Internally Controlled, Multiplex Real-Time Reverse Transcription PCR for Dengue Virus and Yellow Fever Virus Detection. ( 29611509 )
2018
40
Japanese encephalitis virus/yellow fever virus chimera is safe and confers full protection against yellow fever virus in intracerebrally challenged mice. ( 29580643 )
2018
41
Anterior and Intermediate Uveitis Following Yellow Fever Vaccination with Fractional Dose: Case Reports. ( 30153765 )
2018
42
Evaluation of a Booster Dose of Pentavalent Rotavirus Vaccine Coadministered With Measles, Yellow Fever, and Meningitis A Vaccines in 9-Month-Old Malian Infants. ( 29659924 )
2018
43
Immunogenicity and Protection After Vaccination With a Modified Vaccinia Virus Ankara-Vectored Yellow Fever Vaccine in the Hamster Model. ( 30116244 )
2018
44
Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil. ( 30117000 )
2018
45
Management and control of yellow fever virus: Brazilian outbreak January-April, 2018. ( 30122143 )
2018
46
Disseminated mycosis in a patient with yellow fever. ( 30123781 )
2018
47
What Does the Future Hold for Yellow Fever Virus? (II). ( 30134625 )
2018
48
Genomic and epidemiological monitoring of yellow fever virus transmission potential. ( 30139911 )
2018
49
The reemergence of yellow fever. ( 30139914 )
2018
50
Spatio-temporal spillover risk of yellow fever in Brazil. ( 30157908 )
2018

Variations for Yellow Fever

Expression for Yellow Fever

Search GEO for disease gene expression data for Yellow Fever.

Pathways for Yellow Fever

Pathways related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.89 CCL2 CCL5 CCR5 IFNB1 IL4 IL5
2
Show member pathways
13.31 CCL2 CCL5 CCR5 IL4 IL5 IL6
3
Show member pathways
13.21 CCL2 CCL5 CCR5 IL4 IL5 IL6
4
Show member pathways
12.96 CCL2 CCL5 CCR5 IFNB1 IL6 IRF7
5
Show member pathways
12.96 CCL2 CCL5 CCR5 IFNB1 IL4 IL5
6
Show member pathways
12.86 CCL2 CCL5 IFNB1 IL6 IRF7 OAS1
7
Show member pathways
12.45 IFNB1 IRF7 OAS1 RSAD2
8 12.38 CCL2 CCL5 IL4 IRF7 OAS1 RSAD2
9
Show member pathways
12.35 CCR5 IL4 IL5 IL6
10
Show member pathways
12.31 CCR5 IFNB1 IL4 IL5 IL6
11
Show member pathways
12.26 CCL2 IL4 IL5 IL6
12
Show member pathways
12.24 CCL2 CCL5 IL4 IL6 SERPINE1
13 12.22 IFNB1 IL6 IRF7 OAS1
14
Show member pathways
12.19 IFNB1 IL6 IRF7 TLR9
15
Show member pathways
12.12 IFNB1 IL4 IL5 IL6 IRF7 OAS1
16
Show member pathways
12.11 IFNB1 IL4 IL6 TLR9
17
Show member pathways
12.01 CCL2 CCL5 EIF2AK4 IFNB1 IL4 IL6
18
Show member pathways
11.99 CCL2 CCL5 IL4 IL5 IL6
19 11.99 EIF2AK4 IFNB1 IRF7 OAS1
20 11.93 CCL2 IL4 IL6
21
Show member pathways
11.92 CCL2 CCL5 CCR5
22 11.91 IL4 IL5 IL6
23 11.9 CCL2 IL4 IL6
24 11.88 CCL2 CCL5 IFNB1 IL6
25 11.85 IFNB1 IL6 IRF7 SERPINE1
26 11.83 CCL2 IL6 SERPINE1
27 11.82 IL4 IL5 IL6
28 11.8 CCR5 IFNB1 IL6
29 11.78 CCL2 CCL5 IL6
30 11.74 IL4 IL5 IL6
31 11.68 IFNB1 IL6 TLR9
32 11.68 IFNB1 IL5 IRF7 SERPINE1
33 11.63 CCL2 CCL5 IL4 IL6
34 11.47 CCL2 IL6 TLR9
35 11.45 CCL2 CCL5 IL4 IL5 IL6
36 11.25 IL4 IL5 IL6
37 11.2 IFNB1 IL4 IL5 IL6
38 11.09 CCL2 CCL5 IL4 IL5 IL6
39 11.07 CCL5 IFNB1
40
Show member pathways
11.05 IRF7 OAS1
41 11.04 CCL2 CCL5 CCR5 IL4 IL6
42 10.94 CCL2 CCL5 IL4 IL5 IL6

GO Terms for Yellow Fever

Cellular components related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 CCL2 CCL5 IFNB1 IL4 IL5 IL6
2 extracellular region GO:0005576 9.28 CCL2 CCL5 IFNB1 IL4 IL5 IL6

Biological processes related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.99 EIF2AK4 IRF7 OAS1 RSAD2 TLR9
2 inflammatory response GO:0006954 9.91 CCL2 CCL5 CCR5 IL5 IL6 TLR9
3 MAPK cascade GO:0000165 9.87 CCL2 CCL5 CCR5 IL5
4 cellular response to lipopolysaccharide GO:0071222 9.83 CCL2 CCR5 IL6 SERPINE1
5 regulation of signaling receptor activity GO:0010469 9.8 CCL2 CCL5 IFNB1 IL4 IL5 IL6
6 cell chemotaxis GO:0060326 9.78 CCL2 CCL5 CCR5
7 defense response to Gram-negative bacterium GO:0050829 9.77 IL6 SERPINE1 TLR9
8 chemokine-mediated signaling pathway GO:0070098 9.76 CCL2 CCL5 CCR5
9 type I interferon signaling pathway GO:0060337 9.76 IFNB1 IRF7 OAS1 RSAD2
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.75 CCL5 IL4 IL6
11 positive regulation of T cell proliferation GO:0042102 9.73 CCL5 IL4 IL6
12 response to virus GO:0009615 9.72 CCL5 IFNB1 IRF7 OAS1 RSAD2
13 humoral immune response GO:0006959 9.71 CCL2 IFNB1 IL6
14 negative regulation of viral genome replication GO:0045071 9.71 CCL5 IFNB1 OAS1 RSAD2
15 cytokine-mediated signaling pathway GO:0019221 9.7 CCL2 CCL5 CCR5 IFNB1 IL4 IL5
16 monocyte chemotaxis GO:0002548 9.69 CCL2 CCL5 IL6
17 positive regulation of B cell proliferation GO:0030890 9.67 IL4 IL5 TLR9
18 positive regulation of innate immune response GO:0045089 9.65 CCL5 IFNB1
19 eosinophil chemotaxis GO:0048245 9.65 CCL2 CCL5
20 T cell activation involved in immune response GO:0002286 9.65 EIF2AK4 IFNB1
21 positive regulation of JAK-STAT cascade GO:0046427 9.65 CCL5 IL5 IL6
22 positive regulation of chemokine production GO:0032722 9.64 IL6 TLR9
23 positive regulation of monocyte chemotaxis GO:0090026 9.64 CCL5 SERPINE1
24 dendritic cell chemotaxis GO:0002407 9.63 CCL5 CCR5
25 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.63 CCL2 TLR9
26 macrophage chemotaxis GO:0048246 9.62 CCL2 CCL5
27 positive regulation of immunoglobulin secretion GO:0051024 9.61 IL5 IL6
28 immune response GO:0006955 9.56 CCL2 CCL5 CCR5 IL4 IL5 IL6
29 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.55 IL6 RSAD2
30 negative regulation of macrophage apoptotic process GO:2000110 9.54 CCL5 CCR5 IRF7
31 defense response to virus GO:0051607 9.17 EIF2AK4 IFNB1 IL6 IRF7 OAS1 RSAD2
32 positive regulation of transcription by RNA polymerase II GO:0045944 10.09 IFNB1 IL4 IL6 IRF7 SERPINE1 TLR9

Molecular functions related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CCL2 CCL5 IFNB1 IL4 IL5 IL6

Sources for Yellow Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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