MCID: YLL002
MIFTS: 65

Yellow Fever

Categories: Infectious diseases, Liver diseases, Rare diseases, Skin diseases

Aliases & Classifications for Yellow Fever

MalaCards integrated aliases for Yellow Fever:

Name: Yellow Fever 12 77 54 60 56 3 45 15 74
Jungle Yellow Fever 12 74
Urban Yellow Fever 12 74
Yf 54 60
Sylvatic Yellow Fever 12
Yellow Fever, Sylvan 12
Bronze John 60
Yellow Jack 60

Characteristics:

Orphanet epidemiological data:

60
yellow fever
Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 60  
Rare infectious diseases


Summaries for Yellow Fever

CDC : 3 The yellow fever virus is found in tropical and subtropical areas of Africa and South America. The virus is spread to people by the bite of an infected mosquito. Yellow fever is a very rare cause of illness in U.S. travelers. Illness ranges from a fever with aches and pains to severe liver disease with bleeding and yellowing skin (jaundice). Yellow fever infection is diagnosed based on laboratory testing, a person’s symptoms, and travel history. There is no medicine to treat or cure infection. To prevent getting sick from yellow fever, use insect repellent, wear long-sleeved shirts and long pants, and get vaccinated.

MalaCards based summary : Yellow Fever, also known as jungle yellow fever, is related to west nile virus and encephalitis. An important gene associated with Yellow Fever is EIF2AK4 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Sodium Citrate and Citric Acid have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells, and related phenotypes are fever and headache

Disease Ontology : 12 A viral infectious disease that results in infection, has material basis in Yellow fever virus, which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.

Wikipedia : 77 Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever,... more...

Related Diseases for Yellow Fever

Diseases related to Yellow Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
# Related Disease Score Top Affiliating Genes
1 west nile virus 32.4 CCR5 OAS1 RSAD2
2 encephalitis 30.9 CCL2 CCL5 CCR5 IL1B RSAD2
3 human immunodeficiency virus infectious disease 30.4 CCL5 CCR5 IL6
4 chikungunya 30.4 CCL2 CCL5 IL1B IL6 RSAD2
5 typhoid fever 30.4 IL1B IL6 LTA
6 allergic hypersensitivity disease 30.0 CCL5 IL5 SCP2
7 viral encephalitis 29.9 CCL2 CCL5 IL1B IL6
8 influenza 29.9 CCL5 IL1A IRF7 RSAD2
9 meningitis 29.9 CCL2 IL1B IL6
10 dermatitis, atopic 29.7 CCL5 IL17A IL5
11 cytomegalovirus infection 29.7 CCL2 CCL5 IL1B IL6
12 acute respiratory distress syndrome 29.6 IL1B IL6 LTA
13 ulcerative colitis 29.5 IL17A IL1B IL6
14 pertussis 29.4 IL1A IL1B IL6
15 uveitis 29.3 CCL2 IL17A IL1A
16 viral infectious disease 29.2 CCL5 CCR5 IL1B IL6 IRF7 OAS1
17 human immunodeficiency virus type 1 29.2 CCL2 CCL5 CCR5 IL6 LTA
18 multiple sclerosis 28.7 CCL2 CCL5 CCR5 IL17A IL1B IL6
19 malaria 28.5 CCL2 CCL5 IL17A IL1A IL1B IL5
20 psoriatic arthritis 28.5 IL17A IL1A IL1B IL6 LTA
21 rheumatoid arthritis 28.5 CCL2 CCL5 IL17A IL1A IL1B IL6
22 arthritis 28.4 CCL2 IL17A IL1A IL1B IL6 LTA
23 zika fever 11.3
24 kyasanur forest disease 11.0
25 variola major 10.8
26 smallpox 10.8
27 cholera 10.8
28 epidemic typhus 10.7
29 plague 10.7
30 hepatitis 10.5
31 dengue virus 10.4
32 japanese encephalitis 10.4
33 measles 10.4
34 scorpion envenomation 10.4 CCL5 IL6
35 whiplash 10.4 CCL5 CCR5
36 noonan syndrome 3 10.4
37 respiratory syncytial virus infectious disease 10.4 CCL5 IL5
38 obesity-hypoventilation syndrome 10.3 CCL5 IL6
39 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 IL5 IL6
40 vaccinia 10.3
41 recurrent corneal erosion 10.3 IL1B IL6
42 apple allergy 10.3 IL5 SCP2
43 diabetic foot ulcers 10.3 CCL2 IL6
44 noonan syndrome 5 10.3
45 periodontitis, chronic 10.2 IL1B IL6
46 filariasis 10.2 CCL5 IL5 IL6
47 hepatitis a 10.2
48 pulmonary sarcoidosis 10.2 CCL2 CCL5 CCR5
49 purulent labyrinthitis 10.2 CCL2 IL1B
50 denture stomatitis 10.2 CCL2 IL6

Graphical network of the top 20 diseases related to Yellow Fever:



Diseases related to Yellow Fever

Symptoms & Phenotypes for Yellow Fever

Human phenotypes related to Yellow Fever:

60 33 (show all 29)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 60 33 hallmark (90%) Very frequent (99-80%) HP:0001945
2 headache 60 33 hallmark (90%) Very frequent (99-80%) HP:0002315
3 nausea and vomiting 60 33 frequent (33%) Frequent (79-30%) HP:0002017
4 proteinuria 60 33 frequent (33%) Frequent (79-30%) HP:0000093
5 arthralgia 60 33 frequent (33%) Frequent (79-30%) HP:0002829
6 abdominal pain 60 33 frequent (33%) Frequent (79-30%) HP:0002027
7 jaundice 60 33 frequent (33%) Frequent (79-30%) HP:0000952
8 anorexia 60 33 frequent (33%) Frequent (79-30%) HP:0002039
9 myalgia 60 33 frequent (33%) Frequent (79-30%) HP:0003326
10 gastrointestinal hemorrhage 60 33 frequent (33%) Frequent (79-30%) HP:0002239
11 chest pain 60 33 frequent (33%) Frequent (79-30%) HP:0100749
12 diarrhea 60 33 frequent (33%) Frequent (79-30%) HP:0002014
13 spontaneous abortion 60 33 frequent (33%) Frequent (79-30%) HP:0005268
14 oliguria 60 33 frequent (33%) Frequent (79-30%) HP:0100520
15 menometrorrhagia 60 33 frequent (33%) Frequent (79-30%) HP:0400008
16 hypothermia 60 33 occasional (7.5%) Occasional (29-5%) HP:0002045
17 encephalitis 60 33 occasional (7.5%) Occasional (29-5%) HP:0002383
18 hypotension 60 33 occasional (7.5%) Occasional (29-5%) HP:0002615
19 renal insufficiency 60 33 occasional (7.5%) Occasional (29-5%) HP:0000083
20 nephropathy 60 33 occasional (7.5%) Occasional (29-5%) HP:0000112
21 photophobia 60 33 occasional (7.5%) Occasional (29-5%) HP:0000613
22 dehydration 60 33 occasional (7.5%) Occasional (29-5%) HP:0001944
23 arrhythmia 60 33 occasional (7.5%) Occasional (29-5%) HP:0011675
24 congestive heart failure 60 33 occasional (7.5%) Occasional (29-5%) HP:0001635
25 malignant hyperthermia 60 33 occasional (7.5%) Occasional (29-5%) HP:0002047
26 meningitis 60 33 occasional (7.5%) Occasional (29-5%) HP:0001287
27 acute hepatic failure 60 33 occasional (7.5%) Occasional (29-5%) HP:0006554
28 lethargy 60 33 occasional (7.5%) Occasional (29-5%) HP:0001254
29 cardiorespiratory arrest 60 33 occasional (7.5%) Occasional (29-5%) HP:0006543

MGI Mouse Phenotypes related to Yellow Fever:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 CCL5 CCR5 EIF2AK4 IL17A IL1A IL1B
2 homeostasis/metabolism MP:0005376 9.73 CCR5 EIF2AK4 F10 IL17A IL1A IL1B
3 immune system MP:0005387 9.44 CCL2 CCL5 CCR5 EIF2AK4 IL17A IL1A

Drugs & Therapeutics for Yellow Fever

Drugs for Yellow Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sodium Citrate Approved, Investigational Phase 4 68-04-2
2
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
3 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
4 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
5 Citrate Phase 4
6
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 68-26-8, 22737-96-8, 11103-57-4 9904001 445354
7
Lactitol Investigational Phase 3 585-88-6, 585-86-4 493591
8 Heptavalent Pneumococcal Conjugate Vaccine Phase 3,Phase 2
9 Vitamins Phase 3
10 Antioxidants Phase 3
11 Trace Elements Phase 3
12 Micronutrients Phase 3
13 Protective Agents Phase 3
14 Nutrients Phase 3
15 Retinol palmitate Phase 3
16 retinol Phase 3
17
tannic acid Approved Phase 1, Phase 2 1401-55-4
18
Benzocaine Approved, Investigational Phase 1, Phase 2 1994-09-7, 94-09-7 2337
19 Antibodies Phase 2,Phase 1,Not Applicable
20 Immunoglobulins Phase 2,Phase 1,Not Applicable
21 Antimetabolites Phase 2
22 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
23 Anticholesteremic Agents Phase 2
24 Hypolipidemic Agents Phase 2
25 Anti-Inflammatory Agents Phase 2
26 Lipid Regulating Agents Phase 2
27
Aluminum sulfate Approved Phase 1 10043-01-3
28
Mannitol Approved, Investigational Phase 1 69-65-8 6251 453
29
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
30 Immunoglobulins, Intravenous Phase 1
31 Rho(D) Immune Globulin Phase 1
32 gamma-Globulins Phase 1
33 diuretics Phase 1
34 Natriuretic Agents Phase 1
35 Antibodies, Monoclonal Phase 1
36 Antiviral Agents Phase 1
37
leucovorin Approved 58-05-9 143 6006
38
Methotrexate Approved 1959-05-2, 59-05-2 126941
39
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
40
Folic Acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
41
BCG vaccine Investigational Not Applicable
42 Dermatologic Agents
43 Nucleic Acid Synthesis Inhibitors
44 Antirheumatic Agents
45 Vitamin B9
46 Antimetabolites, Antineoplastic
47 Immunosuppressive Agents
48 Vitamin B Complex
49 Folic Acid Antagonists
50 Folate

Interventional clinical trials:

(show top 50) (show all 60)
# Name Status NCT ID Phase Drugs
1 Immunogenicity of Co-administered Yellow Fever and Measles, Mumps, and Rubella (MMR) Vaccines Completed NCT03368495 Phase 4
2 Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali Completed NCT02286895 Phase 4
3 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
4 Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals Recruiting NCT03132311 Phase 4
5 Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) Recruiting NCT02991495 Phase 4
6 Immunity Period After One Dose of Yellow Fever Vaccine in Adults and Children (Paraiba Study) Active, not recruiting NCT02555072 Phase 4
7 Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 Months Old Not yet recruiting NCT03725618 Phase 4
8 The Yellow Fever Vaccine Immunity in HIV Infected Patients : Development of New Assays for Virological and Immunological Monitoring in HIV Infected Patient. Completed NCT01426243 Phase 3
9 Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers Completed NCT01436396 Phase 3
10 A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults Completed NCT01466387 Phase 3
11 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
12 Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Administered With a Yellow Fever Vaccine in Adults Recruiting NCT03342898 Phase 3
13 Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. Active, not recruiting NCT02699099 Phase 3
14 Phase 3 Study of 10-valent Pneumococcal Conjugate Vaccine (PNEUMOSIL) in Healthy Infants Active, not recruiting NCT03197376 Phase 3
15 Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®) Completed NCT00982137 Phase 2
16 Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine Completed NCT01488890 Phase 2
17 The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans Completed NCT01943305 Phase 2
18 Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis Completed NCT00723489 Phase 1, Phase 2 YFV-17D Placebo
19 Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen Completed NCT00436007 Phase 2
20 Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years Completed NCT00788151 Phase 2
21 Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects Completed NCT00730288 Phase 2
22 Impact of GSK Biologicals' 2189242A Vaccine on Nasopharyngeal Carriage, Safety & Immunogenicity in Children & Infants Completed NCT01262872 Phase 2
23 Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South America Completed NCT01187433 Phase 2
24 Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin America Completed NCT00993447 Phase 2
25 Yellow Fever Vaccine on Statin/ Non Statin Subjects Recruiting NCT03116802 Phase 2 Stamaril (live attenuated yellow fever vaccine)
26 Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina Faso Active, not recruiting NCT03614533 Phase 2
27 Trial of Yellow Fever Inactivated Vaccine Completed NCT00995865 Phase 1
28 Yellow Fever Virus Vaccine and Immune Globulin Study Completed NCT00254826 Phase 1
29 A Phase I Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers Completed NCT02743455 Phase 1 ISA-720
30 Phase I Study of West Nile Virus Vaccine Completed NCT00300417 Phase 1 VRC-WNVDNA020-00-VP
31 A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects. Completed NCT02963909 Phase 1
32 Safety and Tolerability of an Antibody Against Yellow Fever Virus (TY014) in Humans Recruiting NCT03776786 Phase 1
33 A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever Not yet recruiting NCT03891420 Phase 1 Galidesivir;Placebo
34 Yellow Fever Vaccination Under Low Dose Methotrexate Therapy Unknown status NCT02383680
35 Yellow Fever Vaccine in Patients With Rheumatic Diseases Completed NCT03430388 Not Applicable
36 Immunity After Two Doses of Yellow Fever Vaccine Completed NCT02572518
37 Clinical Study of Immunity Duration of Yellow Fever Vaccine in Military Completed NCT03338231
38 Characterization of T Cell Responses Following Yellow Fever Virus Vaccination in Healthy Adults Completed NCT00616356
39 Passive Enhanced Safety Surveillance of Stamaril® Vaccine in Korea Completed NCT03541694
40 Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines Completed NCT01765413 Not Applicable
41 The Effect of Extended Yellow Fever Vaccine Information on Symptom Reports Following Vaccination Completed NCT00708630 Not Applicable
42 Seroprevalence and Incidence of Lassa Fever in the Rural Commune of Sibirila, District of Bougouni, Mali Completed NCT02311387
43 Evaluation of the Safety & Performance of 2 Intradermal Safety Devices Completed NCT02556047 Not Applicable
44 Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children Completed NCT01391819 Not Applicable
45 The Interaction Between Measles and DTP Vaccination Completed NCT02710045 Not Applicable
46 "Persistence of Neutralizing Antibodies Against Yellow Fever (YF) in HIV-infected Patients" Recruiting NCT03591003
47 Immune Responses to Yellow Fever Vaccine Recruiting NCT01244802
48 Investigation of Serious Adverse Events Following Vaccination Against Yellow Fever: Emphasis on Genetic Basis and Biological Markers Recruiting NCT03938597
49 Evaluation of an Infant Immunization Encouragement Program in Nigeria Recruiting NCT03870061 Not Applicable
50 Cohort of Patients Infected by an Arbovirus Recruiting NCT01099852

Search NIH Clinical Center for Yellow Fever

Cochrane evidence based reviews: yellow fever

Genetic Tests for Yellow Fever

Anatomical Context for Yellow Fever

MalaCards organs/tissues related to Yellow Fever:

42
Skin, Testes, T Cells, Eye, Kidney, Brain, Nk Cells

Publications for Yellow Fever

Articles related to Yellow Fever:

(show top 50) (show all 2646)
# Title Authors Year
1
Comparative assessment of the replication efficiency of dengue, yellow fever, and chikungunya arboviruses in some insect and mammalian cell lines. ( 31038623 )
2019
2
Detection of antibodies against Icoaraci, Ilhéus, and Saint Louis Encephalitis arboviruses during yellow fever monitoring surveillance in non-human primates (Alouatta caraya) in southern Brazil. ( 31032984 )
2019
3
Novel synthetic nucleotides of notifiable dengue (1-4), Japanese encephalitis, yellow fever and Zika flaviviruses. ( 30652021 )
2019
4
Hepatitis Rebound after Infection with Yellow Fever Virus. ( 30870138 )
2019
5
Simultaneous detection of Dengue virus, Chikungunya virus, Zika virus, Yellow fever virus and West Nile virus. ( 30930286 )
2019
6
Impact of synthetic and biological immunomodulatory therapy on the duration of 17DD yellow fever vaccine-induced immunity in rheumatoid arthritis. ( 30871593 )
2019
7
Rift Valley Fever Virus and Yellow Fever Virus in Urine: A Potential Source of Infection. ( 30888606 )
2019
8
Liver Transplantation for Fulminant Hepatitis Attributed to Yellow Fever. ( 30218577 )
2019
9
Status of the northern muriqui (Brachyteles hypoxanthus) in the time of yellow fever. ( 30474760 )
2019
10
Towards the risk of yellow fever transmission in Europe. ( 30170135 )
2019
11
Perinatal Yellow Fever: A Case Report. ( 29634624 )
2019
12
Emergency Risk Communication: Lessons Learned from a Rapid Review of Recent Gray Literature on Ebola, Zika, and Yellow Fever. ( 29558199 )
2019
13
Improving clinical management of patients with severe yellow fever. ( 31104910 )
2019
14
Predictors of mortality in patients with yellow fever: an observational cohort study. ( 31104909 )
2019
15
Yellow fever outbreak in a rural-urban mixed community of Espírito Santo, Brazil: epidemiological aspects. ( 31093253 )
2019
16
Yellow fever vaccine-associated neurological disease: it is not just the silver generation at risk. ( 31088820 )
2019
17
Yellow Fever and Orthotopic Liver Transplantation: new insights from the autopsy room for an old but reemerging disease. ( 31087672 )
2019
18
Detection of Yellow Fever Virus in Sylvatic Mosquitoes during Disease Outbreaks of 2017⁻2018 in Minas Gerais State, Brazil. ( 31083286 )
2019
19
Fatal Yellow Fever in a kidney transplant patient. ( 31077273 )
2019
20
Yellow fever (YF) vaccination does not increase dengue severity: A retrospective study based on 11,448 dengue notifications in a YF and dengue endemic region. ( 31075425 )
2019
21
Determination of the spatial susceptibility to Yellow Fever using a multicriteria analysis. ( 31066755 )
2019
22
Inactivation of yellow fever virus in plasma after treatment with methylene blue and visible light and in platelet concentrates following treatment with ultraviolet C light. ( 31050821 )
2019
23
Purification of yellow fever virus produced in Vero cells for inactivated vaccine manufacture. ( 31047674 )
2019
24
Host-specific NS5 ubiquitination determines yellow fever virus tropism. ( 31043530 )
2019
25
Combination of surveillance tools reveals that Yellow Fever virus can remain in the same Atlantic Forest area at least for three transmission seasons. ( 31038550 )
2019
26
Brazilian recommendations on the safety and effectiveness of the yellow fever vaccination in patients with chronic immune-mediated inflammatory diseases. ( 31036077 )
2019
27
Microorganism-Based Larval Diets Affect Mosquito Development, Size and Nutritional Reserves in the Yellow Fever Mosquito Aedes aegypti (Diptera: Culicidae). ( 31024326 )
2019
28
Four human diseases with significant public health impact caused by mosquito-borne flaviviruses: West Nile, Zika, dengue and yellow fever. ( 31006554 )
2019
29
The Public Health Benefits and Economic Value of Routine Yellow Fever Vaccination in Colombia. ( 30974312 )
2019
30
Correction to: Complete NMR chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, Aedes aegypti, bound to arachidonic acid. ( 30941584 )
2019
31
Epizootics due to Yellow Fever Virus in São Paulo State, Brazil: viral dissemination to new areas (2016-2017). ( 30940867 )
2019
32
Fractional-dose yellow fever vaccination: an expert review. ( 30937437 )
2019
33
Haemagogus leucocelaenus and Haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in Brazil, 2016-2018. ( 30866775 )
2019
34
Yellow fever vaccination for immunocompromised travellers: unjustified vaccination hesitancy? ( 30850844 )
2019
35
Yellow fever: is Asia prepared for an epidemic? ( 30833057 )
2019
36
A community-level investigation following a yellow fever virus outbreak in South Omo Zone, South-West Ethiopia. ( 30809451 )
2019
37
Yellow Fever-Induced Acute Lung Injury. ( 30802414 )
2019
38
POLICI: A web application for visualising and extracting yellow fever vaccination coverage in Africa. ( 30770224 )
2019
39
Yellow fever virus modulates cytokine mRNA expression and induces activation of caspase 3/7 in the human hepatocarcinoma cell line HepG2. ( 30725182 )
2019
40
Retinal maculopathy in an adult with yellow fever. ( 30712838 )
2019
41
Shortage of yellow fever vaccination: A travel medicine emergency for Chilean travellers. ( 30708130 )
2019
42
Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo. ( 30699122 )
2019
43
Genomic sequence of yellow fever virus from a Dutch traveller returning from the Gambia-Senegal region, the Netherlands, November 2018. ( 30696531 )
2019
44
Factors Affecting Short-Range Host-Seeking for the Yellow Fever Mosquito (Diptera: Culicidae). ( 30689913 )
2019
45
Complete NMR chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, Aedes aegypti, bound to arachidonic acid. ( 30684234 )
2019
46
Evaluation of serological cross-reactivity between yellow fever and other flaviviruses. ( 30660799 )
2019
47
Arguments for a two-dose yellow fever vaccination regimen in travellers. ( 30657977 )
2019
48
Clinical Trial with unlicensed yellow fever vaccine in Japan. ( 30657930 )
2019
49
Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito, Aedes aegypti. ( 30631085 )
2019
50
Assessing the risk of autochthonous yellow fever transmission in Lazio, central Italy. ( 30629583 )
2019

Variations for Yellow Fever

Expression for Yellow Fever

Search GEO for disease gene expression data for Yellow Fever.

Pathways for Yellow Fever

Pathways related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 50)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CCL2 CCL5 CCR5 IL17A IL1A IL1B
2
Show member pathways
13.81 CCL2 CCL5 CCR5 IL17A IL1A IL1B
3
Show member pathways
13.64 CCL2 CCL5 CCR5 IL17A IL1A IL1B
4
Show member pathways
13.51 CCL2 CCL5 IL17A IL1A IL1B IL5
5
Show member pathways
13.38 CCL2 CCL5 CCR5 IL17A IL1A IL1B
6
Show member pathways
13.27 CCL2 CCL5 CCR5 IL17A IL1A IL1B
7
Show member pathways
13.07 CCL2 CCL5 IL1B IL6 IRF7 OAS1
8
Show member pathways
13.04 CCL2 CCL5 CCR5 IL17A IL1A IL1B
9
Show member pathways
12.94 CCL2 CCL5 CCR5 IL1B IL6 IRF7
10
Show member pathways
12.89 CCL2 CCL5 CCR5 IL6 LTA
11
Show member pathways
12.85 IL17A IL1A IL1B IL5 IL6 LTA
12
Show member pathways
12.59 IL17A IL1A IL1B IL5 IL6
13
Show member pathways
12.57 CCR5 IL17A IL1A IL1B IL5 IL6
14
Show member pathways
12.53 CCL2 IL17A IL1B IL6
15 12.49 CCL2 CCL5 IL17A IL1B IRF7 OAS1
16
Show member pathways
12.33 CCL2 IL17A IL1B IL5 IL6
17
Show member pathways
12.31 CCL2 CCL5 IL1B IL6
18
Show member pathways
12.28 CCL2 IL1A IL1B IRF7
19
Show member pathways
12.19 CCL2 CCL5 CCR5 IL1A IL1B
20
Show member pathways
12.05 IL17A IL1B IL6 LTA
21
Show member pathways
12.03 CCL2 CCL5 IL17A IL1A IL1B IL5
22 12.02 CCL2 IL1A IL1B
23 12.02 CCL2 IL17A IL1A IL1B IL6
24 12.01 CCL2 IL1A IL1B IL6
25
Show member pathways
11.97 IL1A IL1B IL5
26 11.96 CCL2 CCL5 IL1B IL6 LTA
27 11.95 IL1A IL1B IL6 IRF7
28
Show member pathways
11.94 CCL2 CCL5 CCR5
29 11.92 CCL2 IL1A IL1B IL6
30 11.9 IL1A IL1B IL5 IL6
31
Show member pathways
11.82 IL17A IL1A IL1B IL5 IL6 IRF7
32 11.81 IL17A IL1B IL5 LTA
33 11.8 IL1A IL1B IL6
34 11.76 CCL2 CCL5 IL17A IL1A IL1B IL6
35 11.74 IL1A IL1B IL6
36 11.71 CCL2 CCL5 IL17A IL1B IL6
37
Show member pathways
11.65 IL1A IL1B IL6
38 11.57 CCL2 CCL5 IL1B IL5 IL6
39 11.56 IL1A IL1B IL5 IL6
40 11.53 CCL2 IL1B IL6
41 11.49 IL1A IL1B IL6
42 11.42 CCL2 CCL5 CCR5 IL1A IL1B IL6
43 11.38 CCL5 IL1A IL1B IL6
44 11.36 IL1A IL1B IL6
45 11.32 IL17A IL1B IL5 IL6
46 11.26 IL1A IL1B IL5 IL6
47 10.91 CCL2 CCL5 IL17A IL1A IL1B IL5
48 10.9 CCL2 IL1B
49 10.53 IL1A IL1B
50 10.46 CCL2 CCL5 IL17A IL1A IL1B IL5

GO Terms for Yellow Fever

Cellular components related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 CCL2 CCL5 F10 IL17A IL1A IL1B
2 extracellular region GO:0005576 9.32 CCL2 CCL5 F10 IL17A IL1A IL1B

Biological processes related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 34)
# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.87 CCL2 CCR5 IL1B IL6
2 regulation of signaling receptor activity GO:0010469 9.86 CCL2 CCL5 IL17A IL1A IL1B IL5
3 cell-cell signaling GO:0007267 9.85 CCL5 CCR5 IL17A IL1B LTA
4 positive regulation of DNA-binding transcription factor activity GO:0051091 9.83 IL1B IL5 IL6
5 MAPK cascade GO:0000165 9.83 CCL2 CCL5 CCR5 IL1B IL5
6 cell chemotaxis GO:0060326 9.81 CCL2 CCL5 CCR5
7 neutrophil chemotaxis GO:0030593 9.81 CCL2 CCL5 IL1B
8 cellular response to interleukin-1 GO:0071347 9.8 CCL2 CCL5 IL17A
9 chemokine-mediated signaling pathway GO:0070098 9.8 CCL2 CCL5 CCR5
10 response to virus GO:0009615 9.8 CCL5 IRF7 OAS1 RSAD2
11 cellular response to organic cyclic compound GO:0071407 9.79 CCL2 CCL5 IL1B
12 type I interferon signaling pathway GO:0060337 9.79 IRF7 OAS1 RSAD2
13 positive regulation of T cell proliferation GO:0042102 9.77 CCL5 IL1B IL6
14 humoral immune response GO:0006959 9.77 CCL2 IL6 LTA
15 defense response to virus GO:0051607 9.77 EIF2AK4 IL6 IRF7 OAS1 RSAD2
16 inflammatory response GO:0006954 9.76 CCL2 CCL5 CCR5 IL17A IL1A IL1B
17 monocyte chemotaxis GO:0002548 9.73 CCL2 CCL5 IL6
18 negative regulation of viral genome replication GO:0045071 9.72 CCL5 OAS1 RSAD2
19 protein kinase B signaling GO:0043491 9.71 CCL2 CCL5 IL1B
20 lipopolysaccharide-mediated signaling pathway GO:0031663 9.69 CCL2 CCL5 IL1B
21 eosinophil chemotaxis GO:0048245 9.66 CCL2 CCL5
22 dendritic cell chemotaxis GO:0002407 9.66 CCL5 CCR5
23 macrophage chemotaxis GO:0048246 9.65 CCL2 CCL5
24 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.65 IL1A IL1B
25 positive regulation of JAK-STAT cascade GO:0046427 9.65 CCL5 IL5 IL6
26 positive regulation of immunoglobulin secretion GO:0051024 9.64 IL5 IL6
27 ectopic germ cell programmed cell death GO:0035234 9.61 IL1A IL1B
28 positive regulation of neuroinflammatory response GO:0150078 9.58 IL1B IL6
29 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.58 IL6 RSAD2
30 positive regulation of glial cell proliferation GO:0060252 9.58 IL1B IL6 LTA
31 cytokine-mediated signaling pathway GO:0019221 9.56 CCL2 CCL5 CCR5 IL17A IL1A IL1B
32 fever generation GO:0001660 9.52 IL1A IL1B
33 negative regulation of macrophage apoptotic process GO:2000110 9.5 CCL5 CCR5 IRF7
34 immune response GO:0006955 9.32 CCL2 CCL5 CCR5 IL17A IL1A IL1B

Molecular functions related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.23 CCL2 CCL5 IL17A IL1A IL1B IL5
2 interleukin-1 receptor binding GO:0005149 8.96 IL1A IL1B
3 protein binding GO:0005515 10 CCL2 CCL5 CCR5 EIF3L F10 IL17A

Sources for Yellow Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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