Zika Virus Congenital Syndrome disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Zika Virus Congenital Syndrome

MalaCards integrated aliases for Zika Virus Congenital Syndrome:

Name: Zika Virus Congenital Syndrome ¹² ¹⁵

Zikv Congenital Infection ¹²

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0080180

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Summaries for Zika Virus Congenital Syndrome

Disease Ontology : ¹² A syndrome that is characterized in neonates by microcephaly, craniofacial disproportion, spasticity, seizures, irritability and brainstem dysfunction including feeding difficulties, ocular abnormalities and findings on neuroimaging such as calcifications, cortical disorders and ventriculomegaly and has material basis in the acquisition of Zika virus infection in utero.

MalaCards based summary : Zika Virus Congenital Syndrome, also known as zikv congenital infection, is related to microcephaly and allergic cutaneous vasculitis. An important gene associated with Zika Virus Congenital Syndrome is ZBP1 (Z-DNA Binding Protein 1).

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Related Diseases for Zika Virus Congenital Syndrome

Diseases in the Congenital Zika Syndrome family:

Zika Virus Congenital Syndrome

Diseases related to Zika Virus Congenital Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)

#	Related Disease	Score	Top Affiliating Genes
1	microcephaly	10.1
2	allergic cutaneous vasculitis	10.0	ZBP1 CD40LG
3	hydrocephalus, congenital, 1	10.0
4	dengue virus	10.0
5	alkuraya-kucinskas syndrome	10.0
6	hemiplegia	10.0
7	guillain-barre syndrome	10.0
8	yellow fever	10.0
9	congenital zika syndrome	10.0
10	hypertonia	10.0
11	hypotonia	10.0
12	spasticity	10.0
13	congenital amyoplasia	10.0
14	latent syphilis	9.5	CD40LG ACMSD
15	primary syphilis	9.4	CD40LG ACMSD

Graphical network of the top 20 diseases related to Zika Virus Congenital Syndrome:

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Symptoms & Phenotypes for Zika Virus Congenital Syndrome

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Drugs & Therapeutics for Zika Virus Congenital Syndrome

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Efficacy of Aquatic Physiotherapy in Stress Level and Muscle Tone of Children Between 3 and 24 Months With Microcephaly by Zika Virus Congenital Syndrome	Completed	NCT03330600

Search NIH Clinical Center for Zika Virus Congenital Syndrome

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Genetic Tests for Zika Virus Congenital Syndrome

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Anatomical Context for Zika Virus Congenital Syndrome

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Publications for Zika Virus Congenital Syndrome

Articles related to Zika Virus Congenital Syndrome:

(show all 14)

#	Title	Authors	PMID	Year
1	[Analysis of the concept of the Zika Virus congenital syndrome]. ⁶¹	Teixeira GA...Enders BC	32022196	2020
2	Exploring the Genetic Predisposition to Zika Virus Congenital Syndrome. ⁶¹	de Barros PVM...de Oliveira JRM	32112648	2020
3	Family fortresses in Zika Congenital Syndrome according to Betty Neuman. ⁶¹	Lima LHSS...Cavalcanti AMTS	32074238	2020
4	The challenge of the laboratory diagnosis in a confirmed congenital Zika virus syndrome in utero: A case report. ⁶¹	Sulleiro E...Soriano-Arandes A	31096455	2019
5	Congenital Zika virus syndrome…what else? Two case reports of severe combined fetal pathologies. ⁶¹	Vouga M...Schaub B	30176812	2018
6	Ultrasound imaging for identification of cerebral damage in congenital Zika virus syndrome: a case series. ⁶¹	Schaub B...Baud D	30169227	2017
7	The phenotypic spectrum of congenital Zika syndrome. ⁶¹	Del Campo M...Zika Embryopathy Task Force-Brazilian Society of Medical Genetics ZETF-SBGM	28328129	2017
8	Zika virus congenital syndrome, the new Z in TORCHZ? Prospects for diagnosis prevention and treatment. ⁶¹	Bryson Y	28027061	2017
9	Zika virus infection and congenital anomalies in the Americas: opportunities for regional action. ⁶¹	Larrandaburu M...Schuler-Faccini L	31384281	2017
10	Zika virus congenital syndrome: experimental models and clinical aspects. ⁶¹	Polonio CM...Peron JPS	28932235	2017
11	Congenital Zika Virus Infection: Beyond Neonatal Microcephaly. ⁶¹	Melo AS...Tanuri A	27695855	2016
12	Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation. ⁶¹	Franca GV...Victora CG	27372398	2016
13	Risk Factors Associated With the Ophthalmoscopic Findings Identified in Infants With Presumed Zika Virus Congenital Infection. ⁶¹	Ventura CV...Belfort R	27228275	2016
14	[Zika virus congenital syndrome]. ⁶¹	Eickmann SH...Silva PF	27462846	2016

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Genes for Zika Virus Congenital Syndrome

Genes related to Zika Virus Congenital Syndrome (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ZBP1	Z-DNA Binding Protein 1	Protein Coding	5.64	DISEASES inferred ¹⁵
2	CD40LG	CD40 Ligand	Protein Coding	5.5	DISEASES inferred ¹⁵
3	GAGE2A	G Antigen 2A	Protein Coding	5.34	DISEASES inferred ¹⁵
4	DDX50	DExD-Box Helicase 50	Protein Coding	5.1	DISEASES inferred ¹⁵
5	RIPK3	Receptor Interacting Serine/Threonine Kinase 3	Protein Coding	4.86	DISEASES inferred ¹⁵
6	TBR1	T-Box Brain Transcription Factor 1	Protein Coding	4.79	DISEASES inferred ¹⁵
7	C1QTNF9	C1q And TNF Related 9	Protein Coding	4.76	DISEASES inferred ¹⁵
8	ACMSD	Aminocarboxymuconate Semialdehyde Decarboxylase	Protein Coding	4.64	DISEASES inferred ¹⁵
9	ACOD1	Aconitate Decarboxylase 1	Protein Coding	4.6	DISEASES inferred ¹⁵

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Variations for Zika Virus Congenital Syndrome

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Expression for Zika Virus Congenital Syndrome

Search GEO for disease gene expression data for Zika Virus Congenital Syndrome.

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Pathways for Zika Virus Congenital Syndrome

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GO Terms for Zika Virus Congenital Syndrome

Biological processes related to Zika Virus Congenital Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of reactive oxygen species metabolic process	GO:2000379	8.62	RIPK3 ACOD1

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