ZNF1
MCID: ZNC008
MIFTS: 22

Zinc Finger Protein 1 (ZNF1)

Aliases & Classifications for Zinc Finger Protein 1

MalaCards integrated aliases for Zinc Finger Protein 1:

Name: Zinc Finger Protein 1 56
Zinc Finger Protein-1 13
Znf1 56

External Ids:

OMIM 56 194490

Summaries for Zinc Finger Protein 1

MalaCards based summary : Zinc Finger Protein 1, also known as zinc finger protein-1, is related to chromophobe renal cell carcinoma and retinoblastoma. An important gene associated with Zinc Finger Protein 1 is GZF1 (GDNF Inducible Zinc Finger Protein 1). Affiliated tissues include b cells, lung and liver.

More information from OMIM: 194490

Related Diseases for Zinc Finger Protein 1

Graphical network of the top 20 diseases related to Zinc Finger Protein 1:



Diseases related to Zinc Finger Protein 1

Symptoms & Phenotypes for Zinc Finger Protein 1

Clinical features from OMIM:

194490

Drugs & Therapeutics for Zinc Finger Protein 1

Search Clinical Trials , NIH Clinical Center for Zinc Finger Protein 1

Genetic Tests for Zinc Finger Protein 1

Anatomical Context for Zinc Finger Protein 1

MalaCards organs/tissues related to Zinc Finger Protein 1:

40
B Cells, Lung, Liver, Prostate, Endothelial, Kidney, Thyroid

Publications for Zinc Finger Protein 1

Articles related to Zinc Finger Protein 1:

(show top 50) (show all 175)
# Title Authors PMID Year
1
Zinc finger protein gene complexes on mouse chromosomes 8 and 11. 56
1981050 1990
2
Chromosomal localization of zinc finger protein genes in man and mouse. 56
2565878 1989
3
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage. 61
32407433 2020
4
The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation. 61
32116123 2020
5
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. 61
32330454 2020
6
Cilia and polycystic kidney disease. 61
32475690 2020
7
Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ. 61
32040550 2020
8
[Knockdown of Fez family zinc finger protein 1 antisense ribonucleic acid 1 (FEZF1-AS1) inhibits invasion and migration of esophageal squamous cell carcinoma cells by blocking JAK2/STAT3 pathway]. 61
32519669 2020
9
Lymphoid Neoplasms With Plasmablastic Differentiation: A Comprehensive Review and Diagnostic Approaches. 61
31725418 2020
10
Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes. 61
32244869 2020
11
Overexpression of Transcription Factor ZNF1 of Glycolysis Improves Bioethanol Productivity under High Glucose Concentration and Enhances Acetic Acid Tolerance of Saccharomyces cerevisiae. 61
32196937 2020
12
Catalase, glutathione, and protein phosphatase 2A-dependent organellar redox signalling regulate aphid fecundity under moderate and high irradiance. 61
31702837 2020
13
A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS. 61
31724694 2020
14
CIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosis. 61
31252164 2019
15
Genetic association of polymorphisms at the intergenic region between PRDM1 and ATG5 with hepatitis B virus infection in Han Chinese patients. 61
31729038 2019
16
Sonic Hedgehog Pathway as the Prognostic Marker in Patients with Extensive Stage Small Cell Lung Cancer. 61
31538424 2019
17
CIZ1 Expression Is Upregulated in Hemangioma of the Tongue. 61
30456533 2019
18
Arabidopsis Cys2/His2 zinc-finger protein MAZ1 is essential for intine formation and exine pattern. 61
31427085 2019
19
[Role of lncRNA Fez family zinc finger protein 1 antisense RNA1 in hepatocellular carcinoma]. 61
31550856 2019
20
PRDM1 levels are associated with clinical diseases in chronic HBV infection and survival of patients with HBV-related hepatocellular carcinoma. 61
31100710 2019
21
RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. 61
30760870 2019
22
PATZ1 is required for efficient HIV-1 infection. 61
31060775 2019
23
Critical role for Piccolo in synaptic vesicle retrieval. 61
31074746 2019
24
Molecular pathogenic pathways in extranodal NK/T cell lymphoma. 61
30935402 2019
25
Expression analysis and characterization of zglp1 in the Chinese tongue sole (Cynoglossus semilaevis). 61
30312653 2019
26
Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency. 61
31057532 2019
27
Corrigendum: Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency. 61
31316524 2019
28
Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients. 61
30696815 2019
29
Screening Gene Mutations in Chinese Patients With Benign Essential Blepharospasm. 61
32038460 2019
30
lncRNA FEZF1-AS1 Is Associated With Prognosis in Lung Adenocarcinoma and Promotes Cell Proliferation, Migration, and Invasion. 61
29510777 2018
31
CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands. 61
30292235 2018
32
A Zinc Finger Transcriptional Repressor Confers Pleiotropic Effects on Rice Growth and Drought Tolerance by Down-Regulating Stress-Responsive Genes. 61
30020522 2018
33
The effect of dexmedetomidine on inflammatory inhibition and microglial polarization in BV-2 cells. 61
30071186 2018
34
Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity. 61
30042095 2018
35
Schwann cell Myc-interacting zinc-finger protein 1 without pox virus and zinc finger: epigenetic implications in a peripheral neuropathy. 61
30127108 2018
36
The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab. 61
30100989 2018
37
POZ/BTB and AT-Hook-Containing Zinc Finger Protein 1 (PATZ1) Suppresses Progression of Ovarian Cancer and Serves as an Independent Prognosis Factor. 61
29926841 2018
38
The Genomics and Molecular Biology of Natural Killer/T-Cell Lymphoma: Opportunities for Translation. 61
29966370 2018
39
Surface expression of Cytokine Receptor-Like Factor 2 increases risk of relapse in pediatric acute lymphoblastic leukemia patients harboring IKZF1 deletions. 61
29899835 2018
40
Trans-suppression of host CDH3 and LOXL4 genes during Cryptosporidium parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNA. 61
29438669 2018
41
Plant Homeodomain Genes Play Important Roles in Cryptococcal Yeast-Hypha Transition. 61
29500261 2018
42
Splicing Site Recognition by Synergy of Three Domains in Splicing Factor RBM10. 61
29450990 2018
43
Loss of One or Two PATZ1 Alleles Has a Critical Role in the Progression of Thyroid Carcinomas Induced by the RET/PTC1 Oncogene. 61
29584698 2018
44
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy. 61
29511296 2018
45
DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. 61
29154038 2018
46
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications. 61
28392331 2018
47
Nuclear delivery of parasite Cdg2_FLc_0220 RNA transcript to epithelial cells during Cryptosporidium parvum infection modulates host gene transcription. 61
29426472 2018
48
FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer. 61
30410597 2018
49
Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination. 61
29217679 2018
50
AIRE: a missing link to explain female susceptibility to autoimmune diseases. 61
29291257 2018

Variations for Zinc Finger Protein 1

Expression for Zinc Finger Protein 1

Search GEO for disease gene expression data for Zinc Finger Protein 1.

Pathways for Zinc Finger Protein 1

GO Terms for Zinc Finger Protein 1

Cellular components related to Zinc Finger Protein 1 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.35 JAZF1 GZF1 FEZF1 CXXC1 CIZ1
2 nucleus GO:0005634 9.17 ZFP1 JAZF1 GZF1 FIZ1 FEZF1 CXXC1

Biological processes related to Zinc Finger Protein 1 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 8.8 JAZF1 GZF1 FEZF1

Molecular functions related to Zinc Finger Protein 1 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.5 ZFP1 JAZF1 GZF1 FIZ1 FEZF1 CXXC1
2 DNA binding GO:0003677 9.46 ZFP1 GZF1 FEZF1 CXXC1
3 nucleic acid binding GO:0003676 9.1 ZFP1 JAZF1 GZF1 FIZ1 FEZF1 CIZ1

Sources for Zinc Finger Protein 1

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11 DGIdb
17 EFO
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32 ICD10
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61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
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72 UMLS via Orphanet
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