ZNF106
MCID: ZNC011
MIFTS: 13

Zinc Finger Protein 106 (ZNF106)

Aliases & Classifications for Zinc Finger Protein 106

MalaCards integrated aliases for Zinc Finger Protein 106:

Name: Zinc Finger Protein 106 56
Zinc Finger Protein-106 13
Znf106 56

External Ids:

OMIM 56 603988

Summaries for Zinc Finger Protein 106

OMIM : 56 Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. See ZNF91 (603971) for general information on ZNFs. (603988)

MalaCards based summary : Zinc Finger Protein 106, also known as zinc finger protein-106, is related to amyotrophic lateral sclerosis type 5 and sudden infant death syndrome. An important gene associated with Zinc Finger Protein 106 is ZNF106 (Zinc Finger Protein 106). Affiliated tissues include myeloid.

Related Diseases for Zinc Finger Protein 106

Diseases in the Zinc Finger Protein 1 family:

Zinc Finger Protein 103 Zinc Finger Protein 105
Zinc Finger Protein 106 Zinc Finger Protein 109

Diseases related to Zinc Finger Protein 106 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 amyotrophic lateral sclerosis type 5 11.3
2 sudden infant death syndrome 10.0

Symptoms & Phenotypes for Zinc Finger Protein 106

Clinical features from OMIM:

603988

Drugs & Therapeutics for Zinc Finger Protein 106

Search Clinical Trials , NIH Clinical Center for Zinc Finger Protein 106

Genetic Tests for Zinc Finger Protein 106

Anatomical Context for Zinc Finger Protein 106

MalaCards organs/tissues related to Zinc Finger Protein 106:

40
Myeloid

Publications for Zinc Finger Protein 106

Articles related to Zinc Finger Protein 106:

# Title Authors PMID Year
1
Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. 56
8467795 1993
2
Genome-wide association study for growth and fatness traits in Chinese Sujiang pigs. 61
31909836 2020
3
Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP. 61
28680062 2017
4
Genetic risk variants for metabolic traits in Arab populations. 61
28106113 2017
5
Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration. 61
26604141 2016
6
Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway. 61
15833274 2005
7
Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1. 61
15656981 2005
8
A major breakpoint cluster domain in murine radiation-induced acute myeloid leukemia. 61
12112312 2002

Variations for Zinc Finger Protein 106

Expression for Zinc Finger Protein 106

Search GEO for disease gene expression data for Zinc Finger Protein 106.

Pathways for Zinc Finger Protein 106

GO Terms for Zinc Finger Protein 106

Cellular components related to Zinc Finger Protein 106 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleolus GO:0005730 8.92 ZNF106 TSPYL1 KNOP1 GNL3

Sources for Zinc Finger Protein 106

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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