ZD1
MCID: ZYG003
MIFTS: 26
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Zygodactyly 1 (ZD1)
Categories:
Bone diseases, Fetal diseases, Genetic diseases, Rare diseases
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MalaCards integrated aliases for Zygodactyly 1:
Classifications:
MalaCards categories:
Global: Fetal diseases Rare diseases Genetic diseases Anatomical: Bone diseases
ICD10:
32
Orphanet: 58
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OMIM®: 57 Syndactyly type I (185900) is an autosomal dominant limb malformation characterized in its classical form by complete or partial webbing between the third and fourth fingers and/or the second and third toes. Zygodactyly is a subtype of type I syndactyly in which webbing of second and third toes occurs without hand involvement (summary by Malik et al., 2005). (609815) (Updated 08-Dec-2022) MalaCards based summary: Zygodactyly 1, also known as syndactyly type 1, weidenreich type, is related to chromosome 2q35 duplication syndrome and craniosynostosis philadelphia type. An important gene associated with Zygodactyly 1 is ZD1 (Zygodactyly 1), and among its related pathways/superpathways are Phospholipase-C Pathway and G-protein signaling_Rap2B regulation pathway. Affiliated tissues include bone, and related phenotype is craniofacial. Disease Ontology: 11 A syndactyly characterized by webbing between the second and third toes in the absence of hand involvement. |
Cochrane evidence based reviews: zygodactyly 1 |
Organs/tissues related to Zygodactyly 1:
MalaCards :
Bone
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Articles related to Zygodactyly 1:
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Cellular components related to Zygodactyly 1 according to GeneCards Suite gene sharing:
Biological processes related to Zygodactyly 1 according to GeneCards Suite gene sharing:
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