Search results for Pyruvic acid

366 hits were found for Pyruvic acid

#	Family	MCID	Name	MIFTS	Score
1		HYP719	Hyperglycinemia, Lactic Acidosis, and Seizures	22	6.570

2		LPC003	Lipoic Acid Synthetase Deficiency	12	3.483

3		PYR041	Pyruvate Kinase Deficiency of Red Cells	57	0.463

4	P	HPT021	Hepatitis	76	0.279

5		PYR022	Pyruvate Dehydrogenase E1-Alpha Deficiency	51	0.257

6	P	LKM002	Leukemia	72	0.255

7	P	BRS047	Breast Cancer	100	0.249

8	P	PRS040	Prostate Cancer	90	0.248

9		PYR037	Pyruvate Carboxylase Deficiency	38	0.240

10	P	DBT026	Diabetes Mellitus, Noninsulin-Dependent	91	0.229

11		PRM236	Primary Biliary Cholangitis	55	0.229

12	P	PNC044	Pancreatitis	64	0.227

13		PRS047	Prostatitis	60	0.225

14	P	PRM006	Primary Biliary Cirrhosis	53	0.224

15	c	BLR024	Biliary Cirrhosis, Primary, 1	36	0.224

16		ISC004	Ischemia	65	0.221

17		END072	Endotheliitis	45	0.221

18	P	HML002	Hemolytic Anemia	62	0.217

19	P	CLR023	Colorectal Cancer	97	0.214

20	P	ADN016	Adenocarcinoma	70	0.207

21		NRN002	Neuronitis	41	0.201

22	P	ENC018	Encephalopathy	62	0.193

23		PYR012	Pyruvate Dehydrogenase E1-Beta Deficiency	23	0.192

24	P	LNG032	Lung Cancer	98	0.184

25	P	LVR013	Liver Disease	75	0.176

26	P	HPT023	Hepatocellular Carcinoma	94	0.175

27		SKN016	Skin Disease	66	0.174

28	P	LCT001	Lactic Acidosis	50	0.173

29		SKN027	Skin Conditions	48	0.173

30	P	DBT009	Diabetes Mellitus	64	0.170

31		CRB009	Cerebritis	41	0.167

32		CHL068	Cholestasis	60	0.163

33	P	GLM045	Glioma	54	0.162

34	P	MYC007	Myocardial Infarction	79	0.160

35		PRS042	Prostate Disease	44	0.158

36		TYP041	Type I	56	0.154

37	P	CRN018	Coronary Artery Anomaly	68	0.151

38	P	NRV007	Nervous System Disease	73	0.151

39		HYP266	Hypoxia	61	0.151

40	P	THY032	Thyroiditis	55	0.150

41	P	NRP001	Neuropathy	63	0.150

42	c	CRN300	Coronary Heart Disease 1	64	0.149

43		AGN016	Aging	64	0.148

44	P	NRB001	Neuroblastoma	72	0.148

45		GST053	Gastric Cancer	77	0.148

46		GST050	Gastrointestinal System Disease	64	0.144

47		ISC006	Ischemic Heart Disease	72	0.144

48	P	KDN018	Kidney Disease	68	0.138

49		SQM006	Squamous Cell Carcinoma	59	0.137

50	P	HRT032	Heart Disease	74	0.134

51	c	SML038	Small Cell Cancer of the Lung	68	0.134

52		MLN008	Melanoma	62	0.130

53	P	EPL164	Epilepsy	69	0.130

54		THR024	Thrombosis	61	0.130

55	c	CNT035	Central Nervous System Disease	63	0.130

56		BRS051	Breast Disease	66	0.129

57		ART140	Arteries, Anomalies of	65	0.129

58	P	ART021	Arteriosclerosis	60	0.129

59	P	MYP004	Myopathy	68	0.129

60		DPR016	Depression	72	0.128

61		CNG034	Congestive Heart Failure	72	0.128

62		OST012	Osteoarthritis	82	0.127

63		ENT004	Enthesopathy	46	0.126

64	P	LYM118	Lymphoma	70	0.126

65		RHM027	Rheumatic Disease	62	0.126

66	P	ESP024	Esophagitis	63	0.125

67	P	OVR042	Ovarian Cancer	81	0.125

68		AST005	Asthma	82	0.124

69		GLC008	Glucose Metabolism Disease	52	0.123

70		CYS001	Cystic Fibrosis	84	0.123

71		ATM095	Autoimmune Disease	64	0.122

72		VRL011	Viral Infectious Disease	63	0.121

73		MYL069	Myeloma, Multiple	83	0.120

74		NRM005	Neuromuscular Disease	60	0.120

75		RTN023	Retinitis	50	0.120

76		MLR004	Malaria	83	0.119

77		CRB025	Carbohydrate Metabolic Disorder	50	0.119

78		LNG099	Lung Disease	67	0.119

79		LPD008	Lipid Metabolism Disorder	58	0.119

80		BRN071	Brain Injury	53	0.118

81		PHN003	Phenylketonuria	73	0.118

82		BRN028	Brain Cancer	72	0.116

83		PNC034	Pancreas Disease	57	0.115

84	c	MTR002	Mitral Valve Insufficiency	46	0.115

85	P	PNC035	Pancreatic Cancer	79	0.114

86		FTT001	Fatty Liver Disease	60	0.114

87	c	HPT001	Hepatitis C	71	0.114

88		SPS003	Spastic Diplegia	54	0.114

89	P	ALZ034	Alzheimer Disease	87	0.112

90	P	PNM007	Pneumonia	69	0.111

91	P	CRV039	Cervicitis	49	0.110

92		NRV006	Nervous System Cancer	60	0.110

93	P	MPL001	Maple Syrup Urine Disease	65	0.110

94		BRN106	Burns	56	0.108

95	c	ACT075	Acute Myocardial Infarction	58	0.108

96		RSP006	Respiratory System Disease	63	0.108

97		GLB002	Glioblastoma	72	0.108

98		PLC008	Placenta Disease	61	0.108

99		HMS001	Hemosiderosis	51	0.107

100		RNL114	Renal Cell Carcinoma, Nonpapillary	59	0.106

101		IMM136	Immune System Disease	56	0.105

102		ADN018	Adenoma	63	0.104

103	P	RHM011	Rheumatoid Arthritis	80	0.104

104		HYP066	Hyperglycemia	63	0.104

105	c	HPT073	Hepatitis C Virus	72	0.103

106		MTB004	Metabolic Acidosis	48	0.103

107	P	MSC005	Muscular Dystrophy	66	0.103

108	P	CRV035	Cervical Cancer	69	0.103

109		DFC004	Deficiency Anemia	61	0.102

110		TRM010	Traumatic Brain Injury	55	0.102

111		HYP060	Hyperinsulinism	56	0.101

112		MYL009	Myelodysplastic Syndrome	70	0.100

113		EWN002	Ewing's Family of Tumors	56	0.100

114	P	DRR001	Diarrhea	56	0.100

115		ERY003	Erythema Multiforme	60	0.099

116		PLM129	Pulmonary Disease, Chronic Obstructive	72	0.099

117		HDN002	Head Injury	47	0.099

118		CRB039	Cerebrovascular Disease	67	0.098

119	P	THL005	Thalassemia	64	0.098

120	c	CHR089	Chronic Kidney Failure	72	0.097

121	c	ART101	Aortic Valve Disease 2	73	0.097

122		NNL002	Nonalcoholic Steatohepatitis	50	0.096

123	P	VSC018	Visceral Steatosis	37	0.095

124	P	ANR048	Aniridia 1	65	0.095

125		DHY010	Dihydrolipoamide Dehydrogenase Deficiency	34	0.095

126	c	FTT008	Fatty Liver Disease, Nonalcoholic 1	39	0.094

127		ANX004	Anoxia	49	0.094

128	P	INF037	Inflammatory Bowel Disease	53	0.092

129	P	MSC033	Muscle Disorders	52	0.092

130		BLD137	Blood Group--Ahonen	17	0.092

131	P	TRC086	Trichohepatoenteric Syndrome 1	54	0.091

132		MSC004	Muscle Tissue Disease	39	0.091

133	P	CTR002	Cataract	60	0.091

134	P	AST007	Astrocytoma	51	0.091

135	P	ART153	Arthrochalasia Ehlers-Danlos Syndrome	21	0.090

136	P	GLY013	Glycogen Storage Disease	61	0.089

137		DMN002	Dementia	68	0.089

138		INS001	Insulinoma	65	0.088

139		CRD119	Cardiac Arrest	62	0.088

140		HYP056	Hypoglycemia	62	0.087

141		SRC014	Sarcoma	68	0.087

142	P	HYP265	Hypotonia	40	0.085

143		TTH006	Tooth Disease	53	0.085

144		CYS013	Cystinuria	63	0.085

145	P	CHR071	Charcot-Marie-Tooth Disease	65	0.084

146		BRN038	Bronchial Disease	56	0.084

147		HMN044	Human Immunodeficiency Virus Type 1	70	0.084

148	P	LYM026	Lymphoblastic Leukemia	64	0.083

149		SKN020	Skin Papilloma	33	0.083

150		BSL008	Basal Ganglia Disease	46	0.083

151		MVM001	Movement Disease	60	0.082

152		PNC041	Pancreatic Ductal Adenocarcinoma	52	0.082

153		GLC003	Glucose Intolerance	56	0.081

154	c	ACT027	Acute Pancreatitis	60	0.081

155	P	MTC069	Mitochondrial Disorders	49	0.080

156		CMM003	Common Wart	41	0.080

157		RFS006	Refsum Disease, Classic	62	0.080

158		PRP001	Propionic Acidemia	62	0.080

159		GLB015	Glioblastoma Multiforme	60	0.079

160	P	DYS154	Dystonia	64	0.079

161		ACR006	Aceruloplasminemia	73	0.079

162	P	ATR011	Atrial Fibrillation	68	0.079

163	P	MTC133	Mitochondrial Myopathy	54	0.079

164		HRT012	Heart Valve Disease	44	0.078

165	P	MYL005	Myelofibrosis	70	0.078

166		SCK005	Sickle Cell Disease	54	0.078

167	P	RTN024	Retinoblastoma	70	0.078

168		ORL011	Oral Cancer	59	0.078

169		LGH007	Leigh Syndrome	67	0.077

170	P	GCH001	Gaucher's Disease	62	0.077

171	P	UTR058	Uterine Anomalies	59	0.077

172		CHL004	Cholelithiasis	50	0.077

173		TRN015	Transient Cerebral Ischemia	56	0.076

174		AMN002	Amino Acid Metabolic Disorder	47	0.076

175		ATN005	Autonomic Dysfunction	50	0.076

176		CRH001	Crohn's Disease	78	0.076

177	P	DYS021	Dysautonomia	43	0.076

178	c	PLM164	Pulmonary Hypertension, Primary, 1	66	0.075

179	c	CNG027	Congenital Hemolytic Anemia	46	0.075

180		THY028	Thyroid Cancer	66	0.075

181	P	OVR049	Ovarian Disease	59	0.075

182	P	MYP006	Myopia	56	0.074

183		LSH001	Leishmaniasis	70	0.074

184		DNT012	Dental Caries	51	0.074

185		ATN002	Autonomic Nervous System Disease	51	0.074

186	c	LKM062	Leukemia, Acute Lymphoblastic	69	0.074

187		ALP041	Alopecia, Neurologic Defects, and Endocrinopathy Syndrome	36	0.074

188	P	ENC011	Encephalomyopathy	40	0.074

189	P	NSP012	Nasopharyngeal Carcinoma	67	0.073

190		MSC157	Muscular Dystrophy, Duchenne Type	68	0.073

191	c	ACT134	Acute Liver Failure	52	0.073

192	P	ATS366	Autism X-Linked 2	43	0.073

193	P	MDL005	Medulloblastoma	75	0.072

194		HPT004	Hepatic Coma	40	0.072

195	P	MTC004	Mitochondrial Encephalomyopathy	43	0.071

196		PLN001	Plantar Wart	34	0.071

197		CHL065	Cholangiocarcinoma	63	0.070

198	P	FRD012	Friedreich Ataxia 1	64	0.070

199		AMN012	Aminoacidopathies	24	0.070

200	P	MNN013	Meningitis	70	0.069

201	P	PRP029	Porphyria	62	0.069

202		INB001	Inborn Amino Acid Metabolism Disorder	16	0.069

203		CRN031	Cranial Nerve Disease	45	0.068

204	P	DBT085	Diabetes Mellitus, Insulin-Dependent	65	0.068

205	c	ACT073	Acute Leukemia	60	0.067

206		SKN019	Skin Melanoma	69	0.067

207		CLR108	Colorectal Adenoma	60	0.067

208		TXC002	Toxic Encephalopathy	55	0.067

209	P	CHR285	Chronic Myelomonocytic Leukemia	62	0.067

210		TRN018	Transitional Cell Carcinoma	61	0.067

211		MTC005	Mitochondrial Metabolism Disease	44	0.066

212		SPN050	Spinocerebellar Degeneration	40	0.066

213	c	INF145	Infantile Liver Failure Syndrome 1	35	0.066

214		ALR002	Al-Raqad Syndrome	31	0.066

215		ARG002	Argininosuccinic Aciduria	57	0.066

216	P	AST055	Asthma-Related Traits 1	30	0.066

217		NNT012	Neonatal Jaundice	51	0.066

218	c	BTT014	Beta-Thalassemia	69	0.065

219	P	RNL007	Renal Tubular Acidosis	52	0.065

220	P	HRD011	Hereditary Spherocytosis	55	0.065

221		ALC007	Alcohol Dependence	65	0.065

222	P	ADL010	Adult Respiratory Distress Syndrome	66	0.065

223	c	ACT210	Acute Respiratory Distress Syndrome	61	0.065

224		ALP046	Alport Syndrome, X-Linked	75	0.064

225		CND006	Candida Glabrata	37	0.064

226	P	PRM002	Primary Hyperoxaluria	53	0.064

227		NSP002	Nasopharyngitis	46	0.063

228	P	TYR004	Tyrosinemia	48	0.063

229	P	HYP061	Hypertrophic Cardiomyopathy	64	0.063

230		CRD137	Cardiogenic Shock	45	0.063

231	P	LNG064	Lung Cancer Susceptibility 3	76	0.062

232		BCK006	Back Pain	44	0.062

233		BRN049	Brain Tumor, Childhood	28	0.062

234		EXT006	Extrahepatic Cholestasis	40	0.061

235		KRN002	Kearns-Sayre Syndrome	60	0.061

236		WST001	West Syndrome	57	0.061

237	c	BLD140	Blood Group, I System	23	0.061

238		OCL011	Ocular Motility Disease	41	0.061

239		MTR031	Motor Neuro-Ophthalmic Disorders	20	0.061

240		PPL022	Papilloma	58	0.060

241		CRV040	Cervix Carcinoma	53	0.060

242		CRV069	Cervix Disease	35	0.060

243		END057	Endometrial Cancer	65	0.059

244	P	SPR120	Supranuclear Palsy, Progressive, 1	70	0.059

245	P	PLM037	Pulmonary Hypertension	75	0.059

246		GST040	Gastric Adenocarcinoma	63	0.059

247		ORL015	Oral Squamous Cell Carcinoma	45	0.058

248		MSC152	Muscular Dystrophy, Becker Type	60	0.058

249		GLC009	Glucosephosphate Dehydrogenase Deficiency	48	0.058

250		ATX038	Ataxia and Polyneuropathy, Adult-Onset	28	0.057

251	P	CRD132	Cardiac Conduction Defect	59	0.057

252		NWB001	Newborn Respiratory Distress Syndrome	52	0.057

253		RSP007	Respiratory Distress Syndrome, Infant	34	0.057

254	P	MTH007	Methemoglobinemia	47	0.057

255		ATX010	Ataxia Neuropathy Spectrum	35	0.057

256		PYR016	Pyridoxine Deficiency	36	0.057

257		HYD012	Hydrops Fetalis	51	0.056

258		HYD059	Hydrops Fetalis, Nonimmune, and/or Atrial Septal Defect	37	0.056

259		SCC001	Succinic Semialdehyde Dehydrogenase Deficiency	54	0.056

260		LKM006	Leukomalacia	41	0.055

261		BRB001	Beriberi	41	0.055

262	c	HYP794	Hyperoxaluria, Primary, Type I	41	0.055

263		SWY001	Swayback	31	0.055

264		DBT007	Diabetic Cataract	32	0.054

265	P	HMP007	Hemophilia	60	0.054

266	P	ANP001	Anaplastic Large Cell Lymphoma	59	0.054

267	c	SCL052	Scleroderma, Familial Progressive	64	0.053

268		PLM010	Pulmonary Edema	56	0.053

269		BLD131	Bladder Urothelial Carcinoma	60	0.053

270		DBT084	Diabetes Mellitus, Ketosis-Prone	52	0.053

271		PRV004	Periventricular Leukomalacia	50	0.053

272		GLL018	Gallbladder Cancer	51	0.051

273		3HY005	3-Hydroxyacyl-Coa Dehydrogenase Deficiency	59	0.051

274		HYP141	Hyperphenylalaninemia	42	0.051

275		ACY010	Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency of	60	0.051

276		LNG073	Long-Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency	60	0.051

277	P	BRS044	Breast Adenocarcinoma	58	0.051

278	P	EST001	Estrogen-Receptor Positive Breast Cancer	51	0.051

279	P	MLG056	Malignant Hyperthermia	59	0.050

280	P	MCR010	Microcephaly	57	0.050

281	P	INF016	Infantile Epileptic Encephalopathy	54	0.050

282		ALC028	Alacrima, Achalasia, and Mental Retardation Syndrome	53	0.050

283		GLL008	Gilles De La Tourette Syndrome	63	0.050

284	P	MYS005	Myositis	63	0.050

285	c	ATM011	Autoimmune Hepatitis	62	0.050

286		ALC006	Alcoholic Hepatitis	62	0.050

287		MTC027	Mitochondrial Trifunctional Protein Deficiency	54	0.050

288		PRP083	Porphyria, Acute Intermittent	61	0.049

289		HPT082	Hepatic Adenomas, Familial	53	0.049

290		GLY085	Glycogen Storage Disease Due to Lactate Dehydrogenase Deficiency	18	0.048

291	P	FTL001	Fetal Alcohol Syndrome	59	0.048

292		CLR030	Clear Cell Renal Cell Carcinoma	49	0.048

293		DWR001	Dwarfism	45	0.048

294		MSC012	Muscular Dystrophy, Duchenne and Becker Type	36	0.048

295		MTC114	Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes	61	0.047

296	c	ALP101	Alpha-Thalassemia	59	0.047

297		FTL016	Fetal Edema	25	0.047

298		TRC120	Tricarboxylic Acid Cycle, Defect of	8	0.047

299	P	DRM010	Dermatomyositis	64	0.047

300		VSC002	Vascular Dementia	58	0.047

301		PLS007	Plasmodium Falciparum Malaria	57	0.047

302		BRT005	Barth Syndrome	51	0.046

303		MCR013	Microphthalmia	60	0.045

304		BTN004	Biotin Deficiency	37	0.045

305		CHR066	Chronic Fatigue Syndrome	66	0.044

306		INT079	Intrahepatic Cholangiocarcinoma	52	0.044

307	c	INH020	Inherited Metabolic Disorder	48	0.044

308		ANH002	Anhidrosis	48	0.043

309		MLG086	Malignant Hyperthermia Susceptibility	38	0.043

310	P	CTR177	Citrullinemia, Type Ii, Adult-Onset	35	0.043

311		PPC001	Pepck 1 Deficiency	33	0.043

312		PDG002	Pdgfrb-Associated Chronic Eosinophilic Leukemia	29	0.043

313	c	LCT020	Lactic Acidosis, Chronic Adult Form	9	0.043

314	c	ACT004	Acute Diarrhea	40	0.043

315		CRB090	Cerebral Hypoxia	46	0.042

316	P	VTL001	Vitelliform Macular Dystrophy	42	0.042

317		ART008	Arteriosclerosis Obliterans	42	0.042

318		PCH007	Pouchitis	41	0.042

319	P	CNG003	Congenital Dyserythropoietic Anemia	41	0.041

320		BLD163	Blood Group, Dombrock System	22	0.041

321		ENC050	Encephalopathy, Neonatal Severe, with Lactic Acidosis and Brain Abnormalities	19	0.041

322		ALP042	Alpha/beta T-Cell Lymphopenia with Gamma/delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity	61	0.040

323		ADP007	Adie Pupil	41	0.040

324		MYC016	Mycobacterium Gordonae	23	0.040

325	P	MCH002	Machado-Joseph Disease	62	0.039

326		FMR004	Fumarase Deficiency	34	0.039

327		ATM052	Autoimmune Disease 1	34	0.039

328		HYP187	Hypertryptophanemia	21	0.039

329		MNN020	Meningococcal Infection	47	0.037

330		BTM003	Beta-Aminoisobutyric Aciduria	15	0.037

331		APR001	Apraxia	53	0.035

332	P	HMG032	Hemoglobin H Disease	52	0.035

333		WRN002	Wernicke-Korsakoff Syndrome	52	0.035

334	P	MYT002	Myotonic Dystrophy	50	0.035

335		BBS001	Babesiosis	50	0.035

336	P	KRN004	Kernicterus	48	0.035

337		HYP774	Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome	47	0.035

338		CRB004	Cerebral Artery Occlusion	46	0.035

339		PRS127	Pearson Marrow-Pancreas Syndrome	44	0.035

340		CRT015	Carotid Artery Occlusion	44	0.035

341		MYC018	Mycobacterium Malmoense	32	0.035

342		MYT026	Myotonia Atrophica	27	0.035

343		MTC108	Mitochondrial Short-Chain Enoyl-Coa Hydratase 1 Deficiency	25	0.035

344	P	HYP050	Hyperinsulinemic Hypoglycemia	54	0.033

345		PLY118	Polyglucosan Body Myopathy 1 with or Without Immunodeficiency	45	0.033

346		AMN003	Amnestic Disorder	44	0.033

347		HYP806	Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy	42	0.033

348		HMN035	Hemangioma-Thrombocytopenia Syndrome	38	0.033

349		HLT002	Halothane Hepatitis	31	0.033

350		GRC001	Gracile Syndrome	31	0.033

351		LPY002	Lipoyltransferase 1 Deficiency	21	0.033

352		LCT008	Lactate Dehydrogenase Deficiency	16	0.033

353		PFF001	Pfeiffer Syndrome	73	0.031

354	c	MLG069	Malignant Hypertension	48	0.031

355		WRN003	Wernicke Encephalopathy	45	0.031

356		MTH064	Methemoglobinemia, Beta-Globin Type	39	0.031

357		ALP011	Alpha-Ketoglutarate Dehydrogenase Deficiency	36	0.031

358		MTH026	Methemoglobinemia Due to Deficiency of Methemoglobin Reductase	33	0.031

359		DHY016	Dehydrated Hereditary Stomatocytosis 1 with or Without Pseudohyperkalemia and/or Perinatal Edema	32	0.031

360	c	HYP555	Hypertriglyceridemia, Transient Infantile	31	0.031

361	c	CNG223	Congenital Methemoglobinemia	30	0.031

362	c	MLT068	Multiple Mitochondrial Dysfunctions Syndrome 1	26	0.031

363	c	THM013	Thiamine Metabolism Dysfunction Syndrome 5	22	0.031

364		MLT150	Multiple Mitochondrial Dysfunctions Syndrome 2 with Hyperglycinemia	21	0.031

365		CRB089	Cerebral Beriberi	20	0.031

366		KRS005	Korsakoff's Amnesic Syndrome	12	0.031