Search results for Trametinib

324 hits were found for Trametinib

# Family MCID Name MIFTS Score
1
P MLN008 Melanoma 69 0.513
2
c MLN055 Melanoma, Cutaneous Malignant 10 52 0.495
3
SKN019 Skin Melanoma 68 0.452
4
P LNG032 Lung Cancer 98 0.285
5
c SML038 Small Cell Cancer of the Lung 65 0.260
6
P ADN016 Adenocarcinoma 64 0.218
7
P CLR023 Colorectal Cancer 99 0.215
8
P EXN002 Exanthem 57 0.206
9
P GLM045 Glioma 63 0.203
10
GLL048 Glial Tumor 45 0.203
11
P MLN066 Melanoma, Cutaneous Malignant 1 70 0.200
12
SPN035 Spindle Cell Sarcoma 53 0.200
13
SRC014 Sarcoma 65 0.197
14
LNG031 Lung Benign Neoplasm 51 0.197
15
SFT003 Soft Tissue Sarcoma 56 0.190
16
THY029 Thyroid Carcinoma 59 0.184
17
P MLG074 Malignant Mesenchymoma 40 0.184
18
c RHB024 Rhabdomyosarcoma 2 67 0.170
19
P GLM040 Glioma Susceptibility 1 81 0.166
20
c MLG068 Malignant Glioma 46 0.166
21
MXD026 Mixed Glioma 45 0.166
22
P NRB001 Neuroblastoma 72 0.162
23
MYL069 Myeloma, Multiple 85 0.158
24
P LYM118 Lymphoma 68 0.158
25
SKN013 Skin Benign Neoplasm 51 0.158
26
PLS009 Plasma Cell Neoplasm 51 0.154
27
c PRM038 Primary Agammaglobulinemia 44 0.154
28
P PNC035 Pancreatic Cancer 84 0.150
29
THY122 Thyroid Gland Cancer 57 0.150
30
P NRF002 Neurofibromatosis 56 0.150
31
LYM019 Lymphosarcoma 46 0.150
32
NRF007 Neurofibroma 64 0.146
33
BRN028 Brain Cancer 74 0.141
34
P SKN015 Skin Carcinoma 66 0.137
35
NRF026 Neurofibromatosis, Type Iv, of Riccardi 26 0.137
36
P HYP086 Hypothyroidism 69 0.132
37
THY030 Thyroid Gland Disease 52 0.132
38
P LNG064 Lung Cancer Susceptibility 3 78 0.128
39
P LKM002 Leukemia 68 0.128
40
c NRF024 Neurofibromatosis, Type I 77 0.123
41
P AST007 Astrocytoma 51 0.123
42
P OVR042 Ovarian Cancer 88 0.117
43
GLB015 Glioblastoma Multiforme 75 0.117
44
THY121 Thyroid Gland Anaplastic Carcinoma 66 0.117
45
P DRR001 Diarrhea 55 0.117
46
HST010 Histiocytosis 48 0.117
47
DWN001 Down Syndrome 70 0.112
48
HYL004 Hyaline Fibromatosis Syndrome 67 0.112
49
P THY023 Thymoma 65 0.112
50
LNG108 Langerhans Cell Histiocytosis 58 0.112
51
P UVT001 Uveitis 57 0.112
52
GNG004 Ganglioglioma 54 0.112
53
c THY107 Thymoma, Familial 52 0.112
54
PLX002 Plexiform Neurofibroma 44 0.112
55
CYT002 Cytokine Deficiency 42 0.112
56
c LKM061 Leukemia, Acute Myeloid 84 0.106
57
CHL065 Cholangiocarcinoma 68 0.106
58
INT079 Intrahepatic Cholangiocarcinoma 51 0.106
59
P PRS040 Prostate Cancer 97 0.100
60
PNC129 Pancreatic Adenocarcinoma 68 0.100
61
P MYL006 Myeloid Leukemia 60 0.100
62
ERD001 Erdheim-Chester Disease 53 0.100
63
P RCT021 Rectum Cancer 52 0.100
64
SHR059 Short Stature, Onychodysplasia, Facial Dysmorphism, and Hypotrichosis 47 0.100
65
48X005 48,xyyy 39 0.100
66
P HPT023 Hepatocellular Carcinoma 100 0.094
67
END057 Endometrial Cancer 74 0.094
68
c FBR046 Fibrosis of Extraocular Muscles, Congenital, 1 57 0.094
69
KRT009 Keratosis 51 0.094
70
c PRS136 Prostate Cancer, Hereditary, 6 33 0.094
71
c PRS130 Prostate Cancer, Hereditary, 8 32 0.094
72
PPL061 Papular Epidermal Nevi with Skyline Basal Cell Layers Syndrome 25 0.094
73
P BRS047 Breast Cancer 97 0.087
74
FCT007 Factor Vii Deficiency 67 0.087
75
P OLG002 Oligodendroglioma 67 0.087
76
ATM095 Autoimmune Disease 62 0.087
77
CMR002 Coumarin Resistance 56 0.087
78
SRS001 Serous Cystadenocarcinoma 52 0.087
79
CYS014 Cystadenocarcinoma 51 0.087
80
CLN045 Colonic Benign Neoplasm 46 0.087
81
APP009 Appendix Adenocarcinoma 44 0.087
82
ATX019 Ataxia with Vitamin E Deficiency 42 0.087
83
HST016 Histiocytic Sarcoma 39 0.087
84
c CHR064 Chronic Monocytic Leukemia 33 0.087
85
LPG001 Lipogranulomatosis 29 0.087
86
c SYS001 Systemic Lupus Erythematosus 86 0.079
87
P RHM011 Rheumatoid Arthritis 80 0.079
88
RNL114 Renal Cell Carcinoma, Nonpapillary 78 0.079
89
P SRC025 Sarcoidosis 1 70 0.079
90
ADL002 Adult Syndrome 70 0.079
91
P ART022 Arthritis 69 0.079
92
LYM133 Lymphoma, Hodgkin, Classic 69 0.079
93
ALP042 Alpha/beta T-Cell Lymphopenia with Gamma/delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity 66 0.079
94
P LPS004 Lupus Erythematosus 61 0.079
95
P KDN017 Kidney Cancer 60 0.079
96
c THY109 Thyroid Cancer, Nonmedullary, 1 56 0.079
97
GNG005 Gangliocytoma 55 0.079
98
HRY003 Hairy Cell Leukemia 55 0.079
99
GNG002 Ganglioneuroma 52 0.079
100
FBR008 Fibrillary Astrocytoma 51 0.079
101
THY123 Thyroid Gland Follicular Carcinoma 48 0.079
102
ACT113 Acute Myeloblastic Leukemia with Maturation 46 0.079
103
CNT019 Central Neurocytoma 46 0.079
104
P BNG032 Benign Mesothelioma 46 0.079
105
PPL018 Papillary Adenocarcinoma 45 0.079
106
c SRC023 Sarcoidosis 2 43 0.079
107
PLM020 Pleomorphic Xanthoastrocytoma 41 0.079
108
THY124 Thyroid Gland Papillary Carcinoma 38 0.079
109
ATM052 Autoimmune Disease 1 37 0.079
110
c AMY091 Amyotrophic Lateral Sclerosis 1 89 0.071
111
P BLD134 Bladder Cancer 79 0.071
112
P LKM071 Leukemia, Chronic Lymphocytic 79 0.071
113
GST019 Gastrointestinal Stromal Tumor 78 0.071
114
c MNN043 Meningioma, Familial 74 0.071
115
OST159 Osteogenic Sarcoma 66 0.071
116
P MTR014 Motor Neuron Disease 65 0.071
117
END041 Endometrial Adenocarcinoma 63 0.071
118
MNN042 Meningioma, Radiation-Induced 62 0.071
119
INT002 Intermittent Claudication 61 0.071
120
LNG099 Lung Disease 60 0.071
121
SQM006 Squamous Cell Carcinoma 60 0.071
122
P CHR285 Chronic Myelomonocytic Leukemia 60 0.071
123
P MLN069 Melanoma, Uveal 59 0.071
124
GRD007 Grade Iii Astrocytoma 59 0.071
125
CNS004 Constipation 58 0.071
126
P FBR017 Fibrosarcoma 56 0.071
127
ENC067 Encephalopathy, Progressive, Early-Onset, with Episodic Rhabdomyolysis 55 0.071
128
AMY027 Amyotrophic Lateral Sclerosis-Parkinsonism/dementia Complex 1 54 0.071
129
P LTR001 Lateral Sclerosis 54 0.071
130
c PRM092 Primary Lateral Sclerosis, Adult, 1 53 0.071
131
TXC002 Toxic Encephalopathy 53 0.071
132
P SML001 Small Cell Carcinoma 52 0.071
133
CLR109 Colorectal Adenocarcinoma 51 0.071
134
PNC041 Pancreatic Ductal Adenocarcinoma 51 0.071
135
SPN021 Spinal Meningioma 50 0.071
136
STM007 Stomatitis 50 0.071
137
c MLG079 Malignant Pleural Mesothelioma 42 0.071
138
SCR001 Secretory Meningioma 41 0.071
139
PPL007 Papillary Serous Adenocarcinoma 40 0.071
140
c OVR114 Ovarian Cancer 1 38 0.071
141
NNL001 Non-Langerhans-Cell Histiocytosis 37 0.071
142
LYM002 Lymphoplasmacyte-Rich Meningioma 36 0.071
143
ANP007 Anaplastic Ganglioglioma 27 0.071
144
ANP032 Anaplastic Pleomorphic Xanthoastrocytoma 16 0.071
145
P PRT133 Proteasome-Associated Autoinflammatory Syndrome 1 81 0.061
146
SQM013 Squamous Cell Carcinoma, Head and Neck 80 0.061
147
CRV035 Cervical Cancer 76 0.061
148
c ATR087 Atrial Standstill 1 75 0.061
149
RNL065 Renal Cell Carcinoma, Papillary, 1 73 0.061
150
LYM143 Lymphoma, Non-Hodgkin, Familial 72 0.061
151
P KDN018 Kidney Disease 72 0.061
152
MYL005 Myelofibrosis 70 0.061
153
c CHR684 Chronic Kidney Disease 70 0.061
154
c NRD033 Neurodegeneration with Brain Iron Accumulation 2a 69 0.061
155
PLY001 Polycythemia Vera 69 0.061
156
P LKM062 Leukemia, Acute Lymphoblastic 69 0.061
157
P LVR013 Liver Disease 68 0.061
158
c JVN004 Juvenile Myelomonocytic Leukemia 67 0.061
159
P TRN020 Turner Syndrome 67 0.061
160
P BLD062 Bile Duct Cancer 67 0.061
161
P ART005 Arteriovenous Malformation 65 0.061
162
P NTR004 Neutropenia 63 0.061
163
P VSC007 Vascular Disease 63 0.061
164
c FNC043 Fanconi Anemia, Complementation Group E 62 0.061
165
BRS099 Breast Ductal Carcinoma 62 0.061
166
P ENC018 Encephalopathy 61 0.061
167
c ACT073 Acute Leukemia 58 0.061
168
INT324 Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, and Genital Anomalies 58 0.061
169
c THY102 Thyroid Cancer, Nonmedullary, 2 58 0.061
170
P GLL018 Gallbladder Cancer 57 0.061
171
c MST023 Mesothelioma, Malignant 57 0.061
172
P PLY018 Polycythemia 56 0.061
173
LNG111 Lung Non-Squamous Non-Small Cell Carcinoma 56 0.061
174
GST050 Gastrointestinal System Disease 56 0.061
175
EPT010 Epithelial-Myoepithelial Carcinoma 55 0.061
176
ACT193 Acute Myeloid Leukemia with Abnormal Bone Marrow Eosinophils Inv(16)(p13q22) or T(16;16)(p13;q22) 54 0.061
177
ACR041 Acromelic Frontonasal Dysostosis 52 0.061
178
c PRM012 Primary Polycythemia 50 0.061
179
P OVR082 Overgrowth Syndrome 50 0.061
180
KLT001 Klatskin's Tumor 50 0.061
181
CLR003 Clear Cell Adenocarcinoma 50 0.061
182
OCL022 Ocular Melanoma 50 0.061
183
c LKM056 Leukemia, Chronic Lymphocytic 2 48 0.061
184
PPL002 Papillary Carcinoma 47 0.061
185
AML029 Ameloblastoma 46 0.061
186
P BRN120 Bronchus Cancer 45 0.061
187
P BCL004 B-Cell Non-Hodgkin Lymphoma 44 0.061
188
P EPT020 Epithelioid Hemangioendothelioma 43 0.061
189
BLR013 Biliary Tract Cancer 42 0.061
190
ACN003 Acneiform Dermatitis 35 0.061
191
OPT032 Optic Pathway Glioma 35 0.061
192
GRM010 Germ Cells Tumors 34 0.061
193
HMN016 Hemangioendothelioma 34 0.061
194
TMR016 Tumor Suppressor Gene on Chromosome 11 28 0.061
195
CLS052 Classic Hairy Cell Leukemia 27 0.061
196
EXT051 Extracranial Arteriovenous Malformation 27 0.061
197
PDG002 Pdgfrb-Associated Chronic Eosinophilic Leukemia 27 0.061
198
BRN148 Bronchial Benign Neoplasm 23 0.061
199
ESP021 Esophageal Cancer 90 0.050
200
P GST053 Gastric Cancer 83 0.050
201
P MDL005 Medulloblastoma 77 0.050
202
P GRF003 Graft-Versus-Host Disease 72 0.050
203
P THR014 Thrombocytopenia 67 0.050
204
LNG039 Lung Squamous Cell Carcinoma 66 0.050
205
P RHB008 Rhabdoid Tumor Predisposition Syndrome 1 65 0.050
206
RHB001 Rhabdoid Cancer 63 0.050
207
CLT003 Colitis 62 0.050
208
ALL026 Allergic Hypersensitivity Disease 62 0.050
209
ATY005 Atypical Teratoid Rhabdoid Tumor 61 0.050
210
DRM006 Dermatitis 61 0.050
211
P PNC044 Pancreatitis 61 0.050
212
RTN017 Retinal Detachment 61 0.050
213
PRG017 Paraganglioma and Gastric Stromal Sarcoma 61 0.050
214
P BNG030 Benign Ependymoma 60 0.050
215
c ACT027 Acute Pancreatitis 60 0.050
216
MLT161 Multinucleated Neurons, Anhydramnios, Renal Dysplasia, Cerebellar Hypoplasia, and Hydranencephaly 57 0.050
217
MCS002 Mucositis 56 0.050
218
JVN009 Juvenile Pilocytic Astrocytoma 55 0.050
219
P ALP008 Alopecia 54 0.050
220
CLL010 Cellular Ependymoma 54 0.050
221
P LNG035 Lung Large Cell Carcinoma 54 0.050
222
BRN038 Bronchial Disease 53 0.050
223
GLM004 Gliomatosis Cerebri 52 0.050
224
PNN001 Panniculitis 51 0.050
225
P PNV001 Panuveitis 50 0.050
226
c LRG001 Large Cell Carcinoma 50 0.050
227
P PNB001 Pineoblastoma 50 0.050
228
DYS073 Dysphagia 50 0.050
229
PRN014 Paronychia 49 0.050
230
GNG008 Ganglioneuroblastoma 48 0.050
231
P KRT005 Keratoacanthoma 48 0.050
232
GRM005 Germ Cell Cancer 47 0.050
233
CNT033 Central Nervous System Cancer 47 0.050
234
FLL008 Folliculitis 46 0.050
235
ANP006 Anaplastic Ependymoma 46 0.050
236
c DRR009 Diarrhea 6 46 0.050
237
PNC056 Pineocytoma 45 0.050
238
MDL002 Medulloepithelioma 44 0.050
239
P EPN001 Ependymoblastoma 44 0.050
240
ANP009 Anaplastic Oligodendroglioma 43 0.050
241
c MLG064 Malignant Ependymoma 41 0.050
242
PNL014 Pineal Gland Cancer 41 0.050
243
c CHR682 Chronic Bilirubin Encephalopathy 39 0.050
244
OVR094 Ovarian Epithelial Cancer 38 0.050
245
MLG142 Malignant Conjunctival Melanoma 36 0.050
246
CHL079 Children's Interstitial Lung Disease 26 0.050
247
c NRF023 Neurofibromatosis, Type Ii 80 0.035
248
IMM167 Immune Deficiency Disease 78 0.035
249
P RSP003 Respiratory Failure 74 0.035
250
SVR004 Severe Combined Immunodeficiency 73 0.035
251
P FML018 Familial Mediterranean Fever 73 0.035
252
P RTN024 Retinoblastoma 73 0.035
253
P FML011 Familial Adenomatous Polyposis 72 0.035
254
HMN044 Human Immunodeficiency Virus Type 1 71 0.035
255
DFC004 Deficiency Anemia 70 0.035
256
MYL009 Myelodysplastic Syndrome 70 0.035
257
P MYS003 Myasthenia Gravis 68 0.035
258
P INF038 Influenza 68 0.035
259
ANM044 Anemia, X-Linked, with or Without Neutropenia and/or Platelet Abnormalities 67 0.035
260
GRN037 Granulomatosis with Polyangiitis 65 0.035
261
CLN015 Colon Adenocarcinoma 65 0.035
262
BRC012 Brucellosis 64 0.035
263
P RHB003 Rhabdomyosarcoma 63 0.035
264
P HML002 Hemolytic Anemia 63 0.035
265
HMT002 Hematologic Cancer 62 0.035
266
c BRN108 Branchiootic Syndrome 1 62 0.035
267
P ESP024 Esophagitis 62 0.035
268
P VSC011 Vasculitis 62 0.035
269
c ANM038 Anemia, Autoimmune Hemolytic 62 0.035
270
P DRM010 Dermatomyositis 61 0.035
271
INT066 Interstitial Lung Disease 60 0.035
272
CRD223 Cardiac Arrhythmia 60 0.035
273
P MYC008 Myocarditis 59 0.035
274
ADN018 Adenoma 59 0.035
275
DSS009 Disseminated Intravascular Coagulation 57 0.035
276
P NRP001 Neuropathy 56 0.035
277
c GRV008 Graves Disease 1 56 0.035
278
HYP005 Hypokalemia 55 0.035
279
VGT001 Vogt-Koyanagi-Harada Disease 55 0.035
280
P HYP076 Hyperthyroidism 55 0.035
281
P DBT005 Diabetes Insipidus 55 0.035
282
PYD001 Pyoderma Gangrenosum 54 0.035
283
P HMP002 Hemophagocytic Lymphohistiocytosis 54 0.035
284
LYM040 Lymphoblastic Lymphoma 54 0.035
285
PRS045 Prostatic Hypertrophy 53 0.035
286
P EMB005 Embryonal Rhabdomyosarcoma 53 0.035
287
IRD001 Iridocyclitis 53 0.035
288
P RTN022 Retinal Vein Occlusion 53 0.035
289
c FML008 Familial Retinoblastoma 53 0.035
290
PTH003 Pathologic Nystagmus 52 0.035
291
TCL027 T-Cell Acute Lymphoblastic Leukemia 51 0.035
292
PRS021 Prostatic Adenoma 51 0.035
293
P PRC012 Pericardial Effusion 51 0.035
294
RSD004 Rosai-Dorfman Disease 51 0.035
295
BLP005 Blepharitis 50 0.035
296
PYD002 Pyoderma 50 0.035
297
SYS003 Systolic Heart Failure 49 0.035
298
PRS129 Prostatic Hyperplasia, Benign 49 0.035
299
47X002 47,xyy 49 0.035
300
INT067 Interstitial Nephritis 48 0.035
301
PRS012 Pars Planitis 48 0.035
302
HMP001 Hemopericardium 48 0.035
303
CRD001 Cardiac Tamponade 47 0.035
304
PLM029 Palmoplantar Keratosis 47 0.035
305
RNL077 Renal Fibrosis 47 0.035
306
RTN001 Retinal Vasculitis 47 0.035
307
CRD137 Cardiogenic Shock 47 0.035
308
CHR008 Choroiditis 46 0.035
309
URT010 Ureteral Obstruction 45 0.035
310
P SBR004 Seborrheic Dermatitis 45 0.035
311
APP010 Appendix Cancer 44 0.035
312
NSP002 Nasopharyngitis 43 0.035
313
ORL015 Oral Squamous Cell Carcinoma 43 0.035
314
MXD050 Mixed Phenotype Acute Leukemia 43 0.035
315
P RRT020 Rare Tumor 41 0.035
316
NTR042 Neutrophilic Dermatosis, Acute Febrile 38 0.035
317
OPT010 Optic Papillitis 38 0.035
318
RFR002 Refractory Hairy Cell Leukemia 33 0.035
319
VRS002 Virus-Associated Trichodysplasia Spinulosa 32 0.035
320
MLT035 Multifocal Choroiditis 32 0.035
321
HRD216 Hereditary Palmoplantar Keratoderma 28 0.035
322
MLN046 Melanoma-Associated Retinopathy 24 0.035
323
INT029 Interleukin-7 Receptor Alpha Deficiency 22 0.035
324
PLG007 Pili Gemini 13 0.035
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