Search results for Trametinib

324 hits were found for Trametinib

#	Family	MCID	Name	MIFTS	Score
1	P	MLN008	Melanoma	69	0.513

2	c	MLN055	Melanoma, Cutaneous Malignant 10	52	0.495

3		SKN019	Skin Melanoma	68	0.452

4	P	LNG032	Lung Cancer	98	0.285

5	c	SML038	Small Cell Cancer of the Lung	65	0.260

6	P	ADN016	Adenocarcinoma	64	0.218

7	P	CLR023	Colorectal Cancer	99	0.215

8	P	EXN002	Exanthem	57	0.206

9	P	GLM045	Glioma	63	0.203

10		GLL048	Glial Tumor	45	0.203

11	P	MLN066	Melanoma, Cutaneous Malignant 1	70	0.200

12		SPN035	Spindle Cell Sarcoma	53	0.200

13		SRC014	Sarcoma	65	0.197

14		LNG031	Lung Benign Neoplasm	51	0.197

15		SFT003	Soft Tissue Sarcoma	56	0.190

16		THY029	Thyroid Carcinoma	59	0.184

17	P	MLG074	Malignant Mesenchymoma	40	0.184

18	c	RHB024	Rhabdomyosarcoma 2	67	0.170

19	P	GLM040	Glioma Susceptibility 1	81	0.166

20	c	MLG068	Malignant Glioma	46	0.166

21		MXD026	Mixed Glioma	45	0.166

22	P	NRB001	Neuroblastoma	72	0.162

23		MYL069	Myeloma, Multiple	85	0.158

24	P	LYM118	Lymphoma	68	0.158

25		SKN013	Skin Benign Neoplasm	51	0.158

26		PLS009	Plasma Cell Neoplasm	51	0.154

27	c	PRM038	Primary Agammaglobulinemia	44	0.154

28	P	PNC035	Pancreatic Cancer	84	0.150

29		THY122	Thyroid Gland Cancer	57	0.150

30	P	NRF002	Neurofibromatosis	56	0.150

31		LYM019	Lymphosarcoma	46	0.150

32		NRF007	Neurofibroma	64	0.146

33		BRN028	Brain Cancer	74	0.141

34	P	SKN015	Skin Carcinoma	66	0.137

35		NRF026	Neurofibromatosis, Type Iv, of Riccardi	26	0.137

36	P	HYP086	Hypothyroidism	69	0.132

37		THY030	Thyroid Gland Disease	52	0.132

38	P	LNG064	Lung Cancer Susceptibility 3	78	0.128

39	P	LKM002	Leukemia	68	0.128

40	c	NRF024	Neurofibromatosis, Type I	77	0.123

41	P	AST007	Astrocytoma	51	0.123

42	P	OVR042	Ovarian Cancer	88	0.117

43		GLB015	Glioblastoma Multiforme	75	0.117

44		THY121	Thyroid Gland Anaplastic Carcinoma	66	0.117

45	P	DRR001	Diarrhea	55	0.117

46		HST010	Histiocytosis	48	0.117

47		DWN001	Down Syndrome	70	0.112

48		HYL004	Hyaline Fibromatosis Syndrome	67	0.112

49	P	THY023	Thymoma	65	0.112

50		LNG108	Langerhans Cell Histiocytosis	58	0.112

51	P	UVT001	Uveitis	57	0.112

52		GNG004	Ganglioglioma	54	0.112

53	c	THY107	Thymoma, Familial	52	0.112

54		PLX002	Plexiform Neurofibroma	44	0.112

55		CYT002	Cytokine Deficiency	42	0.112

56	c	LKM061	Leukemia, Acute Myeloid	84	0.106

57		CHL065	Cholangiocarcinoma	68	0.106

58		INT079	Intrahepatic Cholangiocarcinoma	51	0.106

59	P	PRS040	Prostate Cancer	97	0.100

60		PNC129	Pancreatic Adenocarcinoma	68	0.100

61	P	MYL006	Myeloid Leukemia	60	0.100

62		ERD001	Erdheim-Chester Disease	53	0.100

63	P	RCT021	Rectum Cancer	52	0.100

64		SHR059	Short Stature, Onychodysplasia, Facial Dysmorphism, and Hypotrichosis	47	0.100

65		48X005	48,xyyy	39	0.100

66	P	HPT023	Hepatocellular Carcinoma	100	0.094

67		END057	Endometrial Cancer	74	0.094

68	c	FBR046	Fibrosis of Extraocular Muscles, Congenital, 1	57	0.094

69		KRT009	Keratosis	51	0.094

70	c	PRS136	Prostate Cancer, Hereditary, 6	33	0.094

71	c	PRS130	Prostate Cancer, Hereditary, 8	32	0.094

72		PPL061	Papular Epidermal Nevi with Skyline Basal Cell Layers Syndrome	25	0.094

73	P	BRS047	Breast Cancer	97	0.087

74		FCT007	Factor Vii Deficiency	67	0.087

75	P	OLG002	Oligodendroglioma	67	0.087

76		ATM095	Autoimmune Disease	62	0.087

77		CMR002	Coumarin Resistance	56	0.087

78		SRS001	Serous Cystadenocarcinoma	52	0.087

79		CYS014	Cystadenocarcinoma	51	0.087

80		CLN045	Colonic Benign Neoplasm	46	0.087

81		APP009	Appendix Adenocarcinoma	44	0.087

82		ATX019	Ataxia with Vitamin E Deficiency	42	0.087

83		HST016	Histiocytic Sarcoma	39	0.087

84	c	CHR064	Chronic Monocytic Leukemia	33	0.087

85		LPG001	Lipogranulomatosis	29	0.087

86	c	SYS001	Systemic Lupus Erythematosus	86	0.079

87	P	RHM011	Rheumatoid Arthritis	80	0.079

88		RNL114	Renal Cell Carcinoma, Nonpapillary	78	0.079

89	P	SRC025	Sarcoidosis 1	70	0.079

90		ADL002	Adult Syndrome	70	0.079

91	P	ART022	Arthritis	69	0.079

92		LYM133	Lymphoma, Hodgkin, Classic	69	0.079

93		ALP042	Alpha/beta T-Cell Lymphopenia with Gamma/delta T-Cell Expansion, Severe Cytomegalovirus Infection, and Autoimmunity	66	0.079

94	P	LPS004	Lupus Erythematosus	61	0.079

95	P	KDN017	Kidney Cancer	60	0.079

96	c	THY109	Thyroid Cancer, Nonmedullary, 1	56	0.079

97		GNG005	Gangliocytoma	55	0.079

98		HRY003	Hairy Cell Leukemia	55	0.079

99		GNG002	Ganglioneuroma	52	0.079

100		FBR008	Fibrillary Astrocytoma	51	0.079

101		THY123	Thyroid Gland Follicular Carcinoma	48	0.079

102		ACT113	Acute Myeloblastic Leukemia with Maturation	46	0.079

103		CNT019	Central Neurocytoma	46	0.079

104	P	BNG032	Benign Mesothelioma	46	0.079

105		PPL018	Papillary Adenocarcinoma	45	0.079

106	c	SRC023	Sarcoidosis 2	43	0.079

107		PLM020	Pleomorphic Xanthoastrocytoma	41	0.079

108		THY124	Thyroid Gland Papillary Carcinoma	38	0.079

109		ATM052	Autoimmune Disease 1	37	0.079

110	c	AMY091	Amyotrophic Lateral Sclerosis 1	89	0.071

111	P	BLD134	Bladder Cancer	79	0.071

112	P	LKM071	Leukemia, Chronic Lymphocytic	79	0.071

113		GST019	Gastrointestinal Stromal Tumor	78	0.071

114	c	MNN043	Meningioma, Familial	74	0.071

115		OST159	Osteogenic Sarcoma	66	0.071

116	P	MTR014	Motor Neuron Disease	65	0.071

117		END041	Endometrial Adenocarcinoma	63	0.071

118		MNN042	Meningioma, Radiation-Induced	62	0.071

119		INT002	Intermittent Claudication	61	0.071

120		LNG099	Lung Disease	60	0.071

121		SQM006	Squamous Cell Carcinoma	60	0.071

122	P	CHR285	Chronic Myelomonocytic Leukemia	60	0.071

123	P	MLN069	Melanoma, Uveal	59	0.071

124		GRD007	Grade Iii Astrocytoma	59	0.071

125		CNS004	Constipation	58	0.071

126	P	FBR017	Fibrosarcoma	56	0.071

127		ENC067	Encephalopathy, Progressive, Early-Onset, with Episodic Rhabdomyolysis	55	0.071

128		AMY027	Amyotrophic Lateral Sclerosis-Parkinsonism/dementia Complex 1	54	0.071

129	P	LTR001	Lateral Sclerosis	54	0.071

130	c	PRM092	Primary Lateral Sclerosis, Adult, 1	53	0.071

131		TXC002	Toxic Encephalopathy	53	0.071

132	P	SML001	Small Cell Carcinoma	52	0.071

133		CLR109	Colorectal Adenocarcinoma	51	0.071

134		PNC041	Pancreatic Ductal Adenocarcinoma	51	0.071

135		SPN021	Spinal Meningioma	50	0.071

136		STM007	Stomatitis	50	0.071

137	c	MLG079	Malignant Pleural Mesothelioma	42	0.071

138		SCR001	Secretory Meningioma	41	0.071

139		PPL007	Papillary Serous Adenocarcinoma	40	0.071

140	c	OVR114	Ovarian Cancer 1	38	0.071

141		NNL001	Non-Langerhans-Cell Histiocytosis	37	0.071

142		LYM002	Lymphoplasmacyte-Rich Meningioma	36	0.071

143		ANP007	Anaplastic Ganglioglioma	27	0.071

144		ANP032	Anaplastic Pleomorphic Xanthoastrocytoma	16	0.071

145	P	PRT133	Proteasome-Associated Autoinflammatory Syndrome 1	81	0.061

146		SQM013	Squamous Cell Carcinoma, Head and Neck	80	0.061

147		CRV035	Cervical Cancer	76	0.061

148	c	ATR087	Atrial Standstill 1	75	0.061

149		RNL065	Renal Cell Carcinoma, Papillary, 1	73	0.061

150		LYM143	Lymphoma, Non-Hodgkin, Familial	72	0.061

151	P	KDN018	Kidney Disease	72	0.061

152		MYL005	Myelofibrosis	70	0.061

153	c	CHR684	Chronic Kidney Disease	70	0.061

154	c	NRD033	Neurodegeneration with Brain Iron Accumulation 2a	69	0.061

155		PLY001	Polycythemia Vera	69	0.061

156	P	LKM062	Leukemia, Acute Lymphoblastic	69	0.061

157	P	LVR013	Liver Disease	68	0.061

158	c	JVN004	Juvenile Myelomonocytic Leukemia	67	0.061

159	P	TRN020	Turner Syndrome	67	0.061

160	P	BLD062	Bile Duct Cancer	67	0.061

161	P	ART005	Arteriovenous Malformation	65	0.061

162	P	NTR004	Neutropenia	63	0.061

163	P	VSC007	Vascular Disease	63	0.061

164	c	FNC043	Fanconi Anemia, Complementation Group E	62	0.061

165		BRS099	Breast Ductal Carcinoma	62	0.061

166	P	ENC018	Encephalopathy	61	0.061

167	c	ACT073	Acute Leukemia	58	0.061

168		INT324	Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, and Genital Anomalies	58	0.061

169	c	THY102	Thyroid Cancer, Nonmedullary, 2	58	0.061

170	P	GLL018	Gallbladder Cancer	57	0.061

171	c	MST023	Mesothelioma, Malignant	57	0.061

172	P	PLY018	Polycythemia	56	0.061

173		LNG111	Lung Non-Squamous Non-Small Cell Carcinoma	56	0.061

174		GST050	Gastrointestinal System Disease	56	0.061

175		EPT010	Epithelial-Myoepithelial Carcinoma	55	0.061

176		ACT193	Acute Myeloid Leukemia with Abnormal Bone Marrow Eosinophils Inv(16)(p13q22) or T(16;16)(p13;q22)	54	0.061

177		ACR041	Acromelic Frontonasal Dysostosis	52	0.061

178	c	PRM012	Primary Polycythemia	50	0.061

179	P	OVR082	Overgrowth Syndrome	50	0.061

180		KLT001	Klatskin's Tumor	50	0.061

181		CLR003	Clear Cell Adenocarcinoma	50	0.061

182		OCL022	Ocular Melanoma	50	0.061

183	c	LKM056	Leukemia, Chronic Lymphocytic 2	48	0.061

184		PPL002	Papillary Carcinoma	47	0.061

185		AML029	Ameloblastoma	46	0.061

186	P	BRN120	Bronchus Cancer	45	0.061

187	P	BCL004	B-Cell Non-Hodgkin Lymphoma	44	0.061

188	P	EPT020	Epithelioid Hemangioendothelioma	43	0.061

189		BLR013	Biliary Tract Cancer	42	0.061

190		ACN003	Acneiform Dermatitis	35	0.061

191		OPT032	Optic Pathway Glioma	35	0.061

192		GRM010	Germ Cells Tumors	34	0.061

193		HMN016	Hemangioendothelioma	34	0.061

194		TMR016	Tumor Suppressor Gene on Chromosome 11	28	0.061

195		CLS052	Classic Hairy Cell Leukemia	27	0.061

196		EXT051	Extracranial Arteriovenous Malformation	27	0.061

197		PDG002	Pdgfrb-Associated Chronic Eosinophilic Leukemia	27	0.061

198		BRN148	Bronchial Benign Neoplasm	23	0.061

199		ESP021	Esophageal Cancer	90	0.050

200	P	GST053	Gastric Cancer	83	0.050

201	P	MDL005	Medulloblastoma	77	0.050

202	P	GRF003	Graft-Versus-Host Disease	72	0.050

203	P	THR014	Thrombocytopenia	67	0.050

204		LNG039	Lung Squamous Cell Carcinoma	66	0.050

205	P	RHB008	Rhabdoid Tumor Predisposition Syndrome 1	65	0.050

206		RHB001	Rhabdoid Cancer	63	0.050

207		CLT003	Colitis	62	0.050

208		ALL026	Allergic Hypersensitivity Disease	62	0.050

209		ATY005	Atypical Teratoid Rhabdoid Tumor	61	0.050

210		DRM006	Dermatitis	61	0.050

211	P	PNC044	Pancreatitis	61	0.050

212		RTN017	Retinal Detachment	61	0.050

213		PRG017	Paraganglioma and Gastric Stromal Sarcoma	61	0.050

214	P	BNG030	Benign Ependymoma	60	0.050

215	c	ACT027	Acute Pancreatitis	60	0.050

216		MLT161	Multinucleated Neurons, Anhydramnios, Renal Dysplasia, Cerebellar Hypoplasia, and Hydranencephaly	57	0.050

217		MCS002	Mucositis	56	0.050

218		JVN009	Juvenile Pilocytic Astrocytoma	55	0.050

219	P	ALP008	Alopecia	54	0.050

220		CLL010	Cellular Ependymoma	54	0.050

221	P	LNG035	Lung Large Cell Carcinoma	54	0.050

222		BRN038	Bronchial Disease	53	0.050

223		GLM004	Gliomatosis Cerebri	52	0.050

224		PNN001	Panniculitis	51	0.050

225	P	PNV001	Panuveitis	50	0.050

226	c	LRG001	Large Cell Carcinoma	50	0.050

227	P	PNB001	Pineoblastoma	50	0.050

228		DYS073	Dysphagia	50	0.050

229		PRN014	Paronychia	49	0.050

230		GNG008	Ganglioneuroblastoma	48	0.050

231	P	KRT005	Keratoacanthoma	48	0.050

232		GRM005	Germ Cell Cancer	47	0.050

233		CNT033	Central Nervous System Cancer	47	0.050

234		FLL008	Folliculitis	46	0.050

235		ANP006	Anaplastic Ependymoma	46	0.050

236	c	DRR009	Diarrhea 6	46	0.050

237		PNC056	Pineocytoma	45	0.050

238		MDL002	Medulloepithelioma	44	0.050

239	P	EPN001	Ependymoblastoma	44	0.050

240		ANP009	Anaplastic Oligodendroglioma	43	0.050

241	c	MLG064	Malignant Ependymoma	41	0.050

242		PNL014	Pineal Gland Cancer	41	0.050

243	c	CHR682	Chronic Bilirubin Encephalopathy	39	0.050

244		OVR094	Ovarian Epithelial Cancer	38	0.050

245		MLG142	Malignant Conjunctival Melanoma	36	0.050

246		CHL079	Children's Interstitial Lung Disease	26	0.050

247	c	NRF023	Neurofibromatosis, Type Ii	80	0.035

248		IMM167	Immune Deficiency Disease	78	0.035

249	P	RSP003	Respiratory Failure	74	0.035

250		SVR004	Severe Combined Immunodeficiency	73	0.035

251	P	FML018	Familial Mediterranean Fever	73	0.035

252	P	RTN024	Retinoblastoma	73	0.035

253	P	FML011	Familial Adenomatous Polyposis	72	0.035

254		HMN044	Human Immunodeficiency Virus Type 1	71	0.035

255		DFC004	Deficiency Anemia	70	0.035

256		MYL009	Myelodysplastic Syndrome	70	0.035

257	P	MYS003	Myasthenia Gravis	68	0.035

258	P	INF038	Influenza	68	0.035

259		ANM044	Anemia, X-Linked, with or Without Neutropenia and/or Platelet Abnormalities	67	0.035

260		GRN037	Granulomatosis with Polyangiitis	65	0.035

261		CLN015	Colon Adenocarcinoma	65	0.035

262		BRC012	Brucellosis	64	0.035

263	P	RHB003	Rhabdomyosarcoma	63	0.035

264	P	HML002	Hemolytic Anemia	63	0.035

265		HMT002	Hematologic Cancer	62	0.035

266	c	BRN108	Branchiootic Syndrome 1	62	0.035

267	P	ESP024	Esophagitis	62	0.035

268	P	VSC011	Vasculitis	62	0.035

269	c	ANM038	Anemia, Autoimmune Hemolytic	62	0.035

270	P	DRM010	Dermatomyositis	61	0.035

271		INT066	Interstitial Lung Disease	60	0.035

272		CRD223	Cardiac Arrhythmia	60	0.035

273	P	MYC008	Myocarditis	59	0.035

274		ADN018	Adenoma	59	0.035

275		DSS009	Disseminated Intravascular Coagulation	57	0.035

276	P	NRP001	Neuropathy	56	0.035

277	c	GRV008	Graves Disease 1	56	0.035

278		HYP005	Hypokalemia	55	0.035

279		VGT001	Vogt-Koyanagi-Harada Disease	55	0.035

280	P	HYP076	Hyperthyroidism	55	0.035

281	P	DBT005	Diabetes Insipidus	55	0.035

282		PYD001	Pyoderma Gangrenosum	54	0.035

283	P	HMP002	Hemophagocytic Lymphohistiocytosis	54	0.035

284		LYM040	Lymphoblastic Lymphoma	54	0.035

285		PRS045	Prostatic Hypertrophy	53	0.035

286	P	EMB005	Embryonal Rhabdomyosarcoma	53	0.035

287		IRD001	Iridocyclitis	53	0.035

288	P	RTN022	Retinal Vein Occlusion	53	0.035

289	c	FML008	Familial Retinoblastoma	53	0.035

290		PTH003	Pathologic Nystagmus	52	0.035

291		TCL027	T-Cell Acute Lymphoblastic Leukemia	51	0.035

292		PRS021	Prostatic Adenoma	51	0.035

293	P	PRC012	Pericardial Effusion	51	0.035

294		RSD004	Rosai-Dorfman Disease	51	0.035

295		BLP005	Blepharitis	50	0.035

296		PYD002	Pyoderma	50	0.035

297		SYS003	Systolic Heart Failure	49	0.035

298		PRS129	Prostatic Hyperplasia, Benign	49	0.035

299		47X002	47,xyy	49	0.035

300		INT067	Interstitial Nephritis	48	0.035

301		PRS012	Pars Planitis	48	0.035

302		HMP001	Hemopericardium	48	0.035

303		CRD001	Cardiac Tamponade	47	0.035

304		PLM029	Palmoplantar Keratosis	47	0.035

305		RNL077	Renal Fibrosis	47	0.035

306		RTN001	Retinal Vasculitis	47	0.035

307		CRD137	Cardiogenic Shock	47	0.035

308		CHR008	Choroiditis	46	0.035

309		URT010	Ureteral Obstruction	45	0.035

310	P	SBR004	Seborrheic Dermatitis	45	0.035

311		APP010	Appendix Cancer	44	0.035

312		NSP002	Nasopharyngitis	43	0.035

313		ORL015	Oral Squamous Cell Carcinoma	43	0.035

314		MXD050	Mixed Phenotype Acute Leukemia	43	0.035

315	P	RRT020	Rare Tumor	41	0.035

316		NTR042	Neutrophilic Dermatosis, Acute Febrile	38	0.035

317		OPT010	Optic Papillitis	38	0.035

318		RFR002	Refractory Hairy Cell Leukemia	33	0.035

319		VRS002	Virus-Associated Trichodysplasia Spinulosa	32	0.035

320		MLT035	Multifocal Choroiditis	32	0.035

321		HRD216	Hereditary Palmoplantar Keratoderma	28	0.035

322		MLN046	Melanoma-Associated Retinopathy	24	0.035

323		INT029	Interleukin-7 Receptor Alpha Deficiency	22	0.035

324		PLG007	Pili Gemini	13	0.035